Search Results - "Mihályová, Jana"
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Promising Immunotherapeutic Modalities for B-Cell Lymphoproliferative Disorders
Published in International journal of molecular sciences (25-10-2021)“…Over the last few years, treatment principles have been changed towards more targeted therapy for many B-cell lymphoma subtypes and in chronic lymphocytic…”
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External validation of International Prognostic Score for asymptomatic early stage chronic lymphocytic leukaemia and proposal of an alternative score
Published in British journal of haematology (01-04-2021)“…Summary Most patients with chronic lymphocytic leukaemia (CLL) are nowadays diagnosed without any symptoms and do not require therapy. A prognostic score…”
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Idelalisib plus rituximab versus ibrutinib in the treatment of relapsed/refractory chronic lymphocytic leukaemia: A real‐world analysis from the Chronic Lymphocytic Leukemia Patients Registry (CLLEAR)
Published in British journal of haematology (01-07-2023)“…Summary Idelalisib (idela), a phosphatidylinositol 3‐kinase inhibitor, and ibrutinib, a Bruton tyrosine kinase inhibitor, were the first oral targeted agents…”
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COVID-19 in patients with chronic lymphocytic leukemia: a multicenter analysis by the Czech CLL study group
Published in Annals of hematology (01-04-2023)“…Patients with chronic lymphocytic leukemia (CLL) have a high risk of poor outcomes related to coronavirus disease 2019 (COVID-19). This multicenter cohort…”
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Management of Treatment-Related Infectious Complications in High-Risk Hemato-Oncological Patients via Telemedicine
Published in Cancer management and research (2022)“…Infectious complications, especially febrile neutropenia, in hemato-oncological patients are associated with considerable morbidity, mortality and expenses…”
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Practical aspects of CAR-T cell therapy
Published in Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti (2022)“…Chimeric antigen receptor (CAR) T cell therapy has been gradually building its position in the treatment of hematological malignancies. Currently, there are…”
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CD38 targeted treatment for multiple myeloma
Published in Vnitřní lékar̆stvĭ (01-10-2018)“…CD38 antigen is highly and uniformly expressed on plasma cells and thus represents an ideal target for the treatment of multiple myeloma (MM) with…”
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Osteolytic bone lesions, hypercalcemia and paraprotein, but not a myeloma: case report and review of literature
Published in Vnitřní lékar̆stvĭ (01-04-2020)“…In June 2018, 77-year-old man was referred to The Department of Haematooncology, University Hospital Ostrava, for suspicion of multiple myeloma. This was…”
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PD‐1/PD‐L1 inhibitors in haematological malignancies: update 2017
Published in Immunology (01-11-2017)“…Summary The introduction of PD‐1/PD‐L1 pathway inhibitors is an important landmark in solid oncology with unprecedented practice‐changing activity in various…”
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Venetoclax: A new wave in hematooncology
Published in Experimental hematology (01-05-2018)“…•Cancer cells survive via overexpressed anti-apoptotic BCL2 proteins.•Venetoclax is highly selective BCL2 inhibitor with an acceptable toxicity…”
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Selinexor, selective inhibitor of nuclear export: Unselective bullet for blood cancers
Published in Blood reviews (01-03-2021)“…Exportin 1 (XPO1), also known as chromosome maintenance 1 protein (CRM1), is the main transporter for hundreds of proteins like tumor suppressors, growth…”
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P-092 Monitoring of Anti-BCMA CAR-T Cells and non-CAR-T Immune Subsets in Multiple Myeloma Patients
Published in Clinical lymphoma, myeloma and leukemia (01-09-2024)Get full text
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Single‐agent venetoclax induces MRD‐negative response in relapsed primary plasma cell leukemia with t(11;14)
Published in American journal of hematology (01-01-2019)Get full text
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Second Line Treatment with Bruton Tyrosine Kinase Inhibitor (BTKi) or Bcl-2 Inhibitor (Bcl-2i) in Patients with Chronic Lymphocytic Leukemia (CLL): Primary Analysis of the Czech Study Group for CLL (CSCLL)
Published in Blood (02-11-2023)“…Introduction: Venetoclax in combination with rituximab (VenR) along with either ibrutinib or acalabrutinib monotherapy represent the most common regimens…”
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Cytarabine + G-CSF is more effective than cyclophosphamide + G-CSF as a stem cell mobilization regimen in multiple myeloma
Published in Bone marrow transplantation (Basingstoke) (01-07-2019)“…Cyclophosphamide (Cy) plus granulocyte-colony stimulating factor (G-CSF) is currently a standard regimen for hematopoietic stem cell (HSC) mobilization in…”
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Towards Higher Safety of Haemato-Oncological Patients Undergoing Treatment
Published in Blood (13-11-2019)“…Introduction: Medical care has recently been moving from wards to outpatient clinics due to a growing number of patients, convenient therapeutic approaches and…”
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Characterization of Infectious Complications during the Expected Duration of Cytokine Release Syndrome (CRS) in Patients Receiving CAR T Cell Therapy – Are We over-Treating with Anti-Microbials?
Published in Transplantation and cellular therapy (01-02-2024)“…Management of cytokine release syndrome (CRS) following CAR T cell therapy includes extensive workup to exclude infectious causes of fever. Patients are…”
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Venetoclax plus bortezomib and dexamethasone in heavily pretreated end‐stage myeloma patients without t(11;14): A real‐world cohort
Published in Hematological oncology (01-08-2020)Get full text
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