Search Results - "Miguez, Kayla"
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Rural citizen-patient priorities for healthcare in British Columbia, Canada: findings from a mixed methods study
Published in BMC health services research (18-09-2021)“…Abstract Background The challenge of including citizen-patient voices in healthcare planning is exacerbated in rural communities by regional variation in…”
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Journal Article -
2
Chronic aryl hydrocarbon receptor activity phenocopies smoking‐induced skeletal muscle impairment
Published in Journal of cachexia, sarcopenia and muscle (01-02-2022)“…Background Chronic obstructive pulmonary disease (COPD) patients exhibit skeletal muscle atrophy, denervation, and reduced mitochondrial oxidative capacity…”
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Journal Article -
3
Autophagy ablation in skeletal muscles worsens sepsis-induced muscle wasting, impairs whole-body metabolism, and decreases survival
Published in iScience (18-08-2023)“…Septic patients frequently develop skeletal muscle wasting and weakness, resulting in severe clinical consequences and adverse outcomes. Sepsis triggers…”
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Reduced Mitochondrial Content, Elevated Reactive Oxygen Species, and Modulation by Denervation in Skeletal Muscle of Prefrail or Frail Elderly Women
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (13-11-2019)“…Abstract Denervation and mitochondrial impairment are implicated in age-related skeletal muscle atrophy and may play a role in physical frailty. We recently…”
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Journal Article -
5
Smoke‐induced neuromuscular junction degeneration precedes the fibre type shift and atrophy in chronic obstructive pulmonary disease
Published in The Journal of physiology (01-07-2018)“…Key points Chronic obstructive pulmonary disease (COPD) is largely caused by smoking, and patient limb muscle exhibits a fast fibre shift and atrophy. We show…”
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Journal Article -
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8 and 16 weeks of Chronic Tobacco Smoke Exposure Negatively Impacts Peripheral Motor Axon and Neuromuscular Junction Morphology in the Diaphragm of Mice
Published in The FASEB journal (01-04-2018)“…Introduction Globally, chronic tobacco smoke (TS) exposure is the leading cause of preventable disease, and is the primary risk factor for the development of…”
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Journal Article -
7
Protective roles of autophagy in sepsis‐induced skeletal muscle dysfunction, metabolic derangements and mortality
Published in The FASEB journal (01-04-2019)“…Rationale Sepsis‐induced skeletal muscle dysfunction contributes to physical disability, and increased mortality in intensive care unit patients. Autophagy is…”
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Journal Article -
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Tobacco Smoke Exposure Leads to Denervation-Induced Mitochondrial Impairment in Adult Mice
Published 01-01-2017“…Tobacco smoking is the leading cause of preventable disease in North America and is implicated in the top three causes of death: cardiovascular disease,…”
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Dissertation