Search Results - "Miguelino, Maricel G."
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Evaluation of recombinant factor VIII Fc (Eloctate) activity by thromboelastometry in a multicenter phase 3 clinical trial and correlation with bleeding phenotype
Published in Blood coagulation & fibrinolysis (01-10-2017)“…The aim of this study was to compare the hemostatic efficacy of recombinant factor VIII Fc (rFVIIIFc) (Eloctate) and Advate by ex-vivo rotation…”
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Alprolix (recombinant Factor IX Fc fusion protein): extended half-life product for the prophylaxis and treatment of hemophilia B
Published in Expert review of hematology (01-10-2014)“…Hemophilia B is a genetic disease caused by mutation of the gene for coagulation protein Factor IX. When severe, the disease leads to spontaneous…”
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Clinical utility and patient perspectives on the use of extended half-life rFIXFc in the management of hemophilia B
Published in Patient preference and adherence (01-01-2014)“…Hemophilia B is an X-linked genetic disease caused by mutation of the gene for coagulation protein factor IX (FIX), with an incidence of approximately once…”
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Exchange transfusion therapy and its effects on real-time microcirculation in pediatric sickle cell anemia patients: an intravital microscopy study
Published in Journal of pediatric hematology/oncology (01-04-2012)“…Periodic blood exchange transfusion is a treatment modality commonly used to manage pediatric sickle cell anemia at the University of California Davis Medical…”
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Human Chorionic Villus Stem Cells May Contribute to Endogenous Factor VIII Production during Gestation
Published in Blood (03-12-2015)“…INTRODUCTION: The placenta is an organ that plays a vital role in providing nutrition, elimination of metabolic products and gas exchange for the growing…”
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Liver Tropism and Factor VIII Transgene Expression after Intrauterine Chorionic Villus Stem Cell Transplantation
Published in Blood (03-12-2015)“…INTRODUCTION: Gestation is characterized by rapid mitosis and histogenesis in an immune naïve environment. Growth and development of vital organs are occurring…”
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In Utero Chorionic Villus Stem Cell Transplantation for the Treatment of Hemophilia A
Published in Blood (06-12-2014)“…▪ Pregnancy epitomizes graft tolerance, where the intrauterine allogeneic fetus is protected from rejection by the maternal immune system. Fetal cells are able…”
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Exchange transfusion therapy and its effects on real‐time microcirculation in pediatric sickle cell anemia patients
Published in The FASEB journal (01-04-2012)“…Abstract only The goal of exchange transfusion therapy is to ameliorate vasoocclusion and improve tissue perfusion by removing sickled red blood cells and…”
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Placenta as a Source of Stem Cells for Regenerative Medicine
Published in Current pathobiology reports (01-03-2015)“…The development of effective cell transplantation therapies is currently the focus of biomedical research worldwide, and numerous cell types and sources have…”
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