Search Results - "Miguel Caballero"
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Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury
Published in Science translational medicine (14-12-2016)“…Emerging evidence supports a role for innate immunity and microglia in Alzheimer's disease (AD) pathophysiology. However, no marker related to microglia has…”
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Age‐dependent amyloid deposition is associated with white matter alterations in cognitively normal adults during the adult life span
Published in Alzheimer's & dementia (01-04-2020)“…Introduction Both beta‐amyloid (Ab) deposition and decline in white matter integrity, are brain alterations observed in Alzheimer's disease (AD) and start to…”
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White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease
Published in Brain (London, England : 1878) (01-10-2018)“…See Jacobs and Buckley (doi:10.1093/brain/awy243) for a scientific commentary on this article. Despite the prevalence of white matter alterations in…”
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Three-dimensional optoacoustic tomography using a conventional ultrasound linear detector array: Whole-body tomographic system for small animals
Published in Medical physics (Lancaster) (01-01-2013)“…Purpose: Optoacoustic imaging relies on the detection of ultrasonic waves induced by laser pulse excitations to map optical absorption in biological tissue. A…”
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Left Frontal Hub Connectivity during Memory Performance Supports Reserve in Aging and Mild Cognitive Impairment
Published in Journal of Alzheimer's disease (01-01-2017)“…Reserve in aging and Alzheimer's disease (AD) is defined as maintaining cognition at a relatively high level in the presence of neurodegeneration, an ability…”
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Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease
Published in Science translational medicine (28-08-2019)“…Loss of function of TREM2, a key receptor selectively expressed by microglia in the brain, contributes to the development of Alzheimer's disease (AD). We…”
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Design of new natural antioxidant active packaging: Screening flowsheet from pure essential oils and vegetable oils to ex vivo testing in meat samples
Published in Food control (01-02-2021)“…Two essential oils and seven vegetable oils were tested in an in situ generator of hydroxyl radicals for determining their antioxidant capacity. Then…”
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Antioxidant packaging with encapsulated green tea for fresh minced meat
Published in Innovative food science & emerging technologies (01-06-2017)“…A novel approach to incorporate green tea extract into polyethylene by extrusion technology has been studied. Green tea entrapped by inorganic capsules was…”
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Small vessel disease more than Alzheimer's disease determines diffusion MRI alterations in memory clinic patients
Published in Alzheimer's & dementia (01-11-2020)“…Introduction Microstructural alterations as assessed by diffusion tensor imaging (DTI) are key findings in both Alzheimer's disease (AD) and small vessel…”
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Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology
Published in Molecular neurodegeneration (10-01-2019)“…TREM2 is a transmembrane receptor that is predominantly expressed by microglia in the central nervous system. Rare variants in the TREM2 gene increase the risk…”
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sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early‐stage Alzheimer's disease and associate with neuronal injury markers
Published in EMBO molecular medicine (01-05-2016)“…TREM2 is an innate immune receptor expressed on the surface of microglia. Loss‐of‐function mutations of TREM2 are associated with increased risk of Alzheimer's…”
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Tract-specific white matter hyperintensities disrupt neural network function in Alzheimer's disease
Published in Alzheimer's & dementia (01-03-2017)“…Abstract Introduction White matter hyperintensities (WMHs) increase the risk of Alzheimer's disease (AD). Whether WMHs are associated with the decline of…”
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Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-[beta] pathology
Published in Molecular neurodegeneration (10-01-2019)“…Background TREM2 is a transmembrane receptor that is predominantly expressed by microglia in the central nervous system. Rare variants in the TREM2 gene…”
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Enhanced resting-state functional connectivity between core memory-task activation peaks is associated with memory impairment in MCI
Published in Neurobiology of aging (01-09-2016)“…Abstract Resting-state functional connectivity (FC) is altered in Alzheimer’s disease (AD) but its predictive value for episodic memory impairment is debated…”
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The left frontal cortex supports reserve in aging by enhancing functional network efficiency
Published in Alzheimer's research & therapy (06-03-2018)“…Recent evidence derived from functional magnetic resonance imaging (fMRI) studies suggests that functional hubs (i.e., highly connected brain regions) are…”
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Contribution of acute infarcts to cerebral small vessel disease progression
Published in Annals of neurology (01-10-2019)“…Objective To determine the contribution of acute infarcts, evidenced by diffusion‐weighted imaging positive (DWI+) lesions, to progression of white matter…”
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Within-lesion heterogeneity of subcortical DWI lesion evolution, and stroke outcome: A voxel-based analysis
Published in Journal of cerebral blood flow and metabolism (01-07-2020)“…The fate of subcortical diffusion-weighted imaging (DWI) lesions in stroke patients is highly variable, ranging from complete tissue loss to no visible lesion…”
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Resting-State Connectivity of the Left Frontal Cortex to the Default Mode and Dorsal Attention Network Supports Reserve in Mild Cognitive Impairment
Published in Frontiers in aging neuroscience (07-08-2017)“…Reserve refers to the phenomenon of relatively preserved cognition in disproportion to the extent of neuropathology, e.g., in Alzheimer's disease. A putative…”
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Pb(II) Uptake from Polluted Irrigation Water Using Anatase TiO2 Nanoadsorbent
Published in Molecules (Basel, Switzerland) (07-06-2023)“…The adsorption characteristics of titanium dioxide nanoparticles (nano-TiO2) for the removal of Pb(II) from irrigation water were investigated in this work. To…”
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Caffeine Encapsulation in Metal Organic Framework MIL-53(Al) at Pilot Plant Scale for Preparation of Polyamide Textile Fibers with Cosmetic Properties
Published in ACS applied materials & interfaces (18-05-2022)“…Currently in the marketplace, we can find clothing items able to release skin-friendly ingredients while wearing them. These innovative products with…”
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