Search Results - "Miguel A. González-Cardenete"

In Vitro Cytotoxic Effects of Ferruginol Analogues in Sk-MEL28 Human Melanoma Cells by Shao, Luying, González-Cardenete, Miguel A, Prieto-Garcia, Jose M

“…Ferruginol is a promising abietane-type antitumor diterpene able to induce apoptosis in SK-Mel-28 human malignant melanoma. We aim to increase this activity by…”
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Anticoronavirus Evaluation of Antimicrobial Diterpenoids: Application of New Ferruginol Analogues by Varbanov, Mihayl, Philippot, Stéphanie, González-Cardenete, Miguel A

“…The abietane diterpene (+)-ferruginol ( ), like other natural and semisynthetic abietanes, is distinguished for its interesting pharmacological properties such…”
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Semisynthetic Abietic and Dehydroabietic Acid Derivatives and Triptoquinone Epimers Interfere with LPS-Triggered Activation of Dendritic Cells by Sierra, Jelver A, Gilchrist, Katherine, Tabares-Guevara, Jorge H, Betancur-Galvis, Liliana, Ramirez-Pineda, Jose R, González-Cardenete, Miguel A

“…Abietic acid (AA), dehydroabietic acid (DHA) and triptoquinones (TQs) are bioactive abietane-type diterpenoids, which are present in many edible vegetables and…”
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Antiviral Profiling of C‑18- or C‑19-Functionalized Semisynthetic Abietane Diterpenoids by González-Cardenete, Miguel A., Hamulić, Damir, Miquel-Leal, Francisco J., González-Zapata, Natalia, Jimenez-Jarava, Orlando J., Brand, Yaneth M., Restrepo-Mendez, Laura C., Martinez-Gutierrez, Marlen, Betancur-Galvis, Liliana A., Marín, Maria L.

“…Viral infections affect several million patients annually. Although hundreds of viruses are known to be pathogenic, only a few can be treated in the clinic…”
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Synthesis and Biological Studies of (+)-Liquiditerpenoic Acid A (Abietopinoic Acid) and Representative Analogues: SAR Studies by Hamulić, Damir, Stadler, Marco, Hering, Steffen, Padrón, José M, Bassett, Rachel, Rivas, Fatima, Loza-Mejía, Marco A, Dea-Ayuela, M. Auxiliadora, González-Cardenete, Miguel A

“…The first semisynthesis and biological profiling of the new abietane diterpenoid (+)-liquiditerpenoic acid A (abietopinoic acid) (7) along with several…”
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Antifungal Activity of Amphiphilic Perylene Bisimides by Roa-Linares, Vicky C, Mesa-Arango, Ana C, Zaragozá, Ramón J, González-Cardenete, Miguel A

“…Perylene-based compounds, either naturally occurring or synthetic, have shown interesting biological activities. In this study, we report on the broad-spectrum…”
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Synergistic In Vitro Antiviral Effect of Combinations of Ivermectin, Essential Oils, and 18-(Phthalimid-2-yl)ferruginol against Arboviruses and Herpesvirus by Betancur-Galvis, Liliana, Jimenez-Jarava, Orlando José, Rivas, Fatima, Mendoza-Hernández, William E, González-Cardenete, Miguel A

“…Combining antiviral drugs with different mechanisms of action can help prevent the development of resistance by attacking the infectious agent through multiple…”
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Biological Profiling of Semisynthetic C19-Functionalized Ferruginol and Sugiol Analogues by González-Cardenete, Miguel A, Rivas, Fatima, Basset, Rachel, Stadler, Marco, Hering, Steffen, Padrón, José M, Zaragozá, Ramón J, Dea-Ayuela, María Auxiliadora

“…The abietane-type diterpenoids are significant bioactive compounds exhibiting a varied range of pharmacological properties. In this study, the first synthesis…”
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Discovery of Novel Bioactive Tanshinones and Carnosol Analogues against Breast Cancer by González-Cardenete, Miguel A, González-Zapata, Natalia, Boyd, Lucinda, Rivas, Fatima

“…The abietane diterpenoids ferruginol ( ), tanshinone IIA ( ), and carnosol ( ) are well-known for their interesting pharmacological properties, including…”
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Synthesis and antileishmanial activity of C7- and C12-functionalized dehydroabietylamine derivatives by Dea-Ayuela, M. Auxiliadora, Bilbao-Ramos, Pablo, Bolás-Fernández, Francisco, González-Cardenete, Miguel A.

“…Abietane-type diterpenoids, either naturally occurring or synthetic, have shown a wide range of pharmacological actions, including antiprotozoal properties. In…”
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Synthesis of bodinieric acids A and B, both C-18 and C-19-functionalized abietane diterpenoids: DFT study of the key aldol reaction by Zaragozá, Ramón J, González-Cardenete, Miguel A

“…The first synthesis of C-18- and C-19-bifunctionalized abietane diterpenoids, bodinieric (or callicapoic) acids, via an aldol reaction has been developed. This…”
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Development and Optimization of the Multi-Gram Synthesis of the Antiviral 18-(Phthalimide-2-yl)ferruginol by Francisco Javier Miquel-Leal, Natalia González-Zapata, Orlando José Jimenez-Jarava, Yaneth M. Brand, Liliana Betancur-Galvis, Maria Luisa Marín, Miguel A. González-Cardenete

“…Virus-induced diseases are very common in our society, and we continuously need new treatments for these challenging infections. We discovered by serendipity…”
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Evaluación de la actividad antiherpética in vitro de moléculas híbridas de la combretastatina A4 y diterpenos by Lee S. Agudelo-Gómez, Yaneth Miranda-Brand, David Pérez-Guaita, Miguel A. González-Cardenete, Liliana A. Betancur-Galvis

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