Search Results - "Miguel A. Ares"
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1
Evolutionary and functional history of the Escherichia coli K1 capsule
Published in Nature communications (15-06-2023)“…Escherichia coli is a leading cause of invasive bacterial infections in humans. Capsule polysaccharide has an important role in bacterial pathogenesis, and the…”
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Whole Genome Sequencing of Pediatric Klebsiella pneumoniae Strains Reveals Important Insights Into Their Virulence-Associated Traits
Published in Frontiers in microbiology (13-08-2021)“…Klebsiella pneumoniae is recognized as a common cause of nosocomial infections and outbreaks causing pneumonia, septicemia, and urinary tract infections. This…”
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Two Type VI Secretion Systems of Enterobacter cloacae Are Required for Bacterial Competition, Cell Adherence, and Intestinal Colonization
Published in Frontiers in microbiology (24-09-2020)“…Enterobacter cloacae has emerged as an opportunistic pathogen in healthcare-associated infections. Analysis of the genomic sequences of several E. cloacae…”
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A Mini-Review of Enteroaggregative Escherichia coli with a Specific Target on the Virulence Factors Controlled by the AggR Master Regulator
Published in Polish journal of microbiology (01-12-2023)“…Enteroaggregative (EAEC) strains have been linked to several outbreaks of severe diarrhea around the world, and this bacterium is now commonly resistant to…”
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Transcriptional portrait of M. bovis BCG during biofilm production shows genes differentially expressed during intercellular aggregation and substrate attachment
Published in Scientific reports (28-07-2020)“…Mycobacterium tuberculosis and M. smegmatis form drug-tolerant biofilms through dedicated genetic programs. In support of a stepwise process regulating biofilm…”
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Hypoxia Is Not a Main Stress When Mycobacterium tuberculosis Is in a Dormancy-Like Long-Chain Fatty Acid Environment
Published in Frontiers in cellular and infection microbiology (09-01-2019)“…The capacity of ( ) to sense, respond and adapt to a variable and hostile environment within the host makes it one of the most successful human pathogens…”
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The expression of Longus type 4 pilus of enterotoxigenic Escherichia coli is regulated by LngR and LngS and by H‐NS, CpxR and CRP global regulators
Published in Environmental microbiology (01-05-2017)“…Summary Enterotoxigenic Escherichia coli produces a long type 4 pilus called Longus. The regulatory elements and the environmental signals controlling the…”
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The Flp type IV pilus operon of Mycobacterium tuberculosis is expressed upon interaction with macrophages and alveolar epithelial cells
Published in Frontiers in cellular and infection microbiology (20-09-2022)“…The genome of Mycobacterium tuberculosis ( Mtb ) harbors the genetic machinery for assembly of the F imbrial l ow-molecular-weight p rotein (Flp) type IV…”
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cAMP Receptor Protein Positively Regulates the Expression of Genes Involved in the Biosynthesis of Klebsiella oxytoca Tilivalline Cytotoxin
Published in Frontiers in microbiology (30-09-2021)“…is a resident of the human gut. However, certain toxigenic strains exist that secrete the nonribosomal peptide tilivalline (TV) cytotoxin. TV is a…”
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10
Long-chain fatty acids alter transcription of Helicobacter pylori virulence and regulatory genes
Published in PeerJ (San Francisco, CA) (01-11-2021)“…Infection with Helicobacter pylori is one of the most important risk factors for developing gastric cancer (GC). The type IV secretion system (T4SS) encoded in…”
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The Lack of the TetR-Like Repressor Gene BCG_2177c (Rv2160A) May Help Mycobacteria Overcome Intracellular Redox Stress and Survive Longer Inside Macrophages When Surrounded by a Lipid Environment
Published in Frontiers in cellular and infection microbiology (07-07-2022)“…Mycobacteria, like other microorganisms, survive under different environmental variations by expressing an efficient adaptive response, oriented by regulatory…”
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Additional regulatory activities of MrkH for the transcriptional expression of the Klebsiella pneumoniae mrk genes: Antagonist of H-NS and repressor
Published in PloS one (09-03-2017)“…Klebsiella pneumoniae is a common opportunistic pathogen causing nosocomial infections. One of the main virulence determinants of K. pneumoniae is the type 3…”
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13
The Coli Surface Antigen CS3 of Enterotoxigenic Escherichia coli Is Differentially Regulated by H-NS, CRP, and CpxRA Global Regulators
Published in Frontiers in microbiology (25-07-2019)“…Enterotoxigenic produces a myriad of adhesive structures collectively named colonization factors (CFs). CS3 is a CF, which is assembled into fine wiry…”
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The Two-Component System CpxRA Represses Salmonella Pathogenicity Island 2 by Directly Acting on the ssrAB Regulatory Operon
Published in Microbiology spectrum (26-10-2022)“…The acquisition of Salmonella pathogenicity island 2 (SPI-2) conferred on Salmonella the ability to survive and replicate within host cells. The bicistronic…”
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15
The nucleoid protein HU positively regulates the expression of type VI secretion systems in Enterobacter cloacae
Published in mSphere (29-05-2024)“…is an emerging pathogen isolated in healthcare-associated infections. A major virulence factor of this bacterium is the type VI secretion system (T6SS). The…”
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Molecular Characterization of SehB, a Type II Antitoxin of Salmonella enterica Serotype Typhimurium: Amino Acid Residues Involved in DNA-Binding, Homodimerization, Toxin Interaction, and Virulence
Published in Frontiers in microbiology (09-04-2020)“…serotype Typhimurium is a bacterium that causes gastroenteritis and diarrhea in humans. The genome of Typhimurium codes for diverse virulence factors, among…”
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The Interaction of Klebsiella pneumoniae With Lipid Rafts-Associated Cholesterol Increases Macrophage-Mediated Phagocytosis Due to Down Regulation of the Capsule Polysaccharide
Published in Frontiers in cellular and infection microbiology (17-07-2019)“…successfully colonizes host tissues by recognizing and interacting with cholesterol present on membrane-associated lipid rafts. In this study, we evaluated the…”
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Transcriptional Profiling of Type II Toxin-Antitoxin Genes of Helicobacter pylori under Different Environmental Conditions: Identification of HP0967-HP0968 System
Published in Frontiers in microbiology (22-11-2016)“…is a Gram-negative bacterium that colonizes the human gastric mucosa and is responsible for causing peptic ulcers and gastric carcinoma. The expression of…”
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Transcriptional and Mycolic Acid Profiling in Mycobacterium bovis BCG In Vitro Show an Effect for c-di-GMP and Overlap between Dormancy and Biofilms
Published in Journal of microbiology and biotechnology (30-06-2020)“…Mycobacterium tuberculosis produces mycolic acids which are relevant for persistence, recalcitrance to antibiotics and defiance to host immunity. c-di-GMP is a…”
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The CpxRA two-component system represses gene expression of the heat-labile toxin of enterotoxigenic Escherichia coli
Published in Journal of medical microbiology (01-04-2023)“…Enterotoxigenic (ETEC) strains produce at least one of two types of enterotoxins: the heat-labile (LT) and heat-stable (ST) toxins, which are responsible for…”
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