Search Results - "Miguel, Joaquim"

Could 3D models of cancer enhance drug screening? by Brancato, Virginia, Oliveira, Joaquim Miguel, Correlo, Vitor Manuel, Reis, Rui Luis, Kundu, Subhas C.

“…Cancer is a multifaceted pathology, where cellular and acellular players interact to drive cancer progression and, in the worst-case, metastasis. The current…”
Get full text

Progress of microfluidic hydrogel-based scaffolds and organ-on-chips for the cartilage tissue engineering by Tolabi, Hamidreza, Davari, Niyousha, Khajehmohammadi, Mehran, Malektaj, Haniyeh, Nazemi, Katayoun, Vahedi, Samaneh, Ghalandari, Behafarid, Reis, R. L., Ghorbani, Farnaz, Oliveira, Joaquim M.

“…Cartilage degeneration is among the fundamental reasons behind disability and pain across the globe. Numerous approaches have been employed to treat cartilage…”
Get full text

Cardiac lymphatics are heterogeneous in origin and respond to injury by Klotz, Linda, Norman, Sophie, Vieira, Joaquim Miguel, Masters, Megan, Rohling, Mala, Dubé, Karina N., Bollini, Sveva, Matsuzaki, Fumio, Carr, Carolyn A., Riley, Paul R.

“…The lymphatic vasculature is a blind-ended network crucial for tissue-fluid homeostasis, immune surveillance and lipid absorption from the gut. Recent evidence…”
Get full text

The cardiac lymphatic system stimulates resolution of inflammation following myocardial infarction by Vieira, Joaquim Miguel, Norman, Sophie, Villa Del Campo, Cristina, Cahill, Thomas J, Barnette, Damien N, Gunadasa-Rohling, Mala, Johnson, Louise A, Greaves, David R, Carr, Carolyn A, Jackson, David G, Riley, Paul R

“…Myocardial infarction (MI) arising from obstruction of the coronary circulation engenders massive cardiomyocyte loss and replacement by non-contractile scar…”
Get full text

Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart by Cahill, Thomas J, Sun, Xin, Ravaud, Christophe, Villa Del Campo, Cristina, Klaourakis, Konstantinos, Lupu, Irina-Elena, Lord, Allegra M, Browne, Cathy, Jacobsen, Sten Eirik W, Greaves, David R, Jackson, David G, Cowley, Sally A, James, William, Choudhury, Robin P, Vieira, Joaquim Miguel, Riley, Paul R

“…Macrophages are components of the innate immune system with key roles in tissue inflammation and repair. It is now evident that macrophages also support…”
Get full text

The dual effect of abscisic acid on stomata by Pantin, Florent, Monnet, Fabien, Jannaud, Dorothée, Costa, Joaquim Miguel, Renaud, Jeanne, Muller, Bertrand, Simonneau, Thierry, Genty, Bernard

“…The classical view that the drought-related hormone ABA simply acts locally at the guard cell level to induce stomatal closure is questioned by differences…”
Get full text

Adaptable hydrogel with reversible linkages for regenerative medicine: Dynamic mechanical microenvironment for cells by Tong, Zongrui, Jin, Lulu, Oliveira, Joaquim Miguel, Reis, Rui L., Zhong, Qi, Mao, Zhengwei, Gao, Changyou

“…Hydrogels are three-dimensional platforms that serve as substitutes for native extracellular matrix. These materials are starting to play important roles in…”
Get full text

Engineering nanoparticles for targeting rheumatoid arthritis: Past, present, and future trends by Oliveira, Isabel Matos, Gonçalves, Cristiana, Reis, Rui Luís, Oliveira, Joaquim Miguel

“…Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial joint inflammation and cartilage and bone tissue destruction. Although…”
Get full text

Multi-Sensing Techniques with Ultrasound for Musculoskeletal Assessment: A Review by de Oliveira, Jonathan, de Souza, Mauren Abreu, Assef, Amauri Amorin, Maia, Joaquim Miguel

“…The study of muscle contractions generated by the muscle-tendon unit (MTU) plays a critical role in medical diagnoses, monitoring, rehabilitation, and…”
Get full text

The extracellular matrix protein agrin is essential for epicardial epithelial-to-mesenchymal transition during heart development by Sun, Xin, Malandraki-Miller, Sophia, Kennedy, Tahnee, Bassat, Elad, Klaourakis, Konstantinos, Zhao, Jia, Gamen, Elisabetta, Vieira, Joaquim Miguel, Tzahor, Eldad, Riley, Paul R

“…During heart development, epicardial cells residing within the outer layer undergo epithelial-mesenchymal transition (EMT) and migrate into the underlying…”
Get full text

Opportunities and Limitations of Crop Phenotyping in Southern European Countries by Costa, Joaquim Miguel, Marques da Silva, Jorge, Pinheiro, Carla, Barón, Matilde, Mylona, Photini, Centritto, Mauro, Haworth, Matthew, Loreto, Francesco, Uzilday, Baris, Turkan, Ismail, Oliveira, Maria Margarida

“…The Mediterranean climate is characterized by hot dry summers and frequent droughts. Mediterranean crops are frequently subjected to high evapotranspiration…”
Get full text

Current strategies for treatment of intervertebral disc degeneration: substitution and regeneration possibilities by van Uden, Sebastião, Silva-Correia, Joana, Oliveira, Joaquim Miguel, Reis, Rui Luís

“…Intervertebral disc degeneration has an annual worldwide socioeconomic impact masked as low back pain of over 70 billion euros. This disease has a high…”
Get full text

BRG1-SWI/SNF-dependent regulation of the Wt1 transcriptional landscape mediates epicardial activity during heart development and disease by Vieira, Joaquim Miguel, Howard, Sara, Villa del Campo, Cristina, Bollini, Sveva, Dubé, Karina N., Masters, Megan, Barnette, Damien N., Rohling, Mala, Sun, Xin, Hankins, Laura E., Gavriouchkina, Daria, Williams, Ruth, Metzger, Daniel, Chambon, Pierre, Sauka-Spengler, Tatjana, Davies, Benjamin, Riley, Paul R.

“…Epicardium-derived cells (EPDCs) contribute cardiovascular cell types during development and in adulthood respond to Thymosin β4 (Tβ4) and myocardial…”
Get full text

Selective requirements for NRP1 ligands during neurovascular patterning by Vieira, Joaquim Miguel, Schwarz, Quenten, Ruhrberg, Christiana

“…Blood vessels and neurons share several types of guidance cues and cell surface receptors to control their behaviour during embryogenesis. The transmembrane…”
Get full text

Suturable regenerated silk fibroin scaffold reinforced with 3D-printed polycaprolactone mesh: biomechanical performance and subcutaneous implantation by Cengiz, Ibrahim Fatih, Pereira, Helder, Espregueira-Mendes, João, Kwon, Il Keun, Reis, Rui L., Oliveira, Joaquim Miguel

“…The menisci have crucial roles in the knee, chondroprotection being the primary. Meniscus repair or substitution is favored in the clinical management of the…”
Get full text

Actin filament reorganisation controlled by the SCAR/WAVE complex mediates stomatal response to darkness by Isner, Jean‐Charles, Xu, Zaoxu, Costa, Joaquim Miguel, Monnet, Fabien, Batstone, Thomas, Ou, Xiaobin, Deeks, Michael J., Genty, Bernard, Jiang, Kun, Hetherington, Alistair M.

“…Stomata respond to darkness by closing to prevent excessive water loss during the night. Although the reorganisation of actin filaments during stomatal closure…”
Get full text

Predicting Crop Evapotranspiration under Non-Standard Conditions Using Machine Learning Algorithms, a Case Study for Vitis vinifera L. cv Tempranillo by Egipto, Ricardo, Aquino, Arturo, Costa, Joaquim Miguel, Andújar, José Manuel

“…This study focuses on assessing the accuracy of supervised machine learning regression algorithms (MLAs) in predicting actual crop evapotranspiration (ETc act)…”
Get full text

Micro-CT - a digital 3D microstructural voyage into scaffolds: a systematic review of the reported methods and results by Cengiz, Ibrahim Fatih, Oliveira, Joaquim Miguel, Reis, Rui L

“…Cell behavior is the key to tissue regeneration. Given the fact that most of the cells used in tissue engineering are anchorage-dependent, their behavior…”
Get full text

Learning ADC maps from accelerated radial k‐space diffusion‐weighted MRI in mice using a deep CNN‐transformer model by Li, Yuemeng, Joaquim, Miguel Romanello, Pickup, Stephen, Song, Hee Kwon, Zhou, Rong, Fan, Yong

“…Purpose To accelerate radially sampled diffusion weighted spin‐echo (Rad‐DW‐SE) acquisition method for generating high quality ADC maps. Methods A deep…”
Get full text

Cerium d-Block Element (Co, Ni) Bimetallic Oxides as Catalysts for the Methanation of CO2: Effect of Pressure by Joaquim Miguel Badalo Branco, Ana Cristina Ferreira, Joana Filipa Martinho

“…Nickel– and cobalt–cerium bimetallic oxides were used as catalysts for the methanation of CO2 under pressure. The catalysts’ activity increases with pressure…”
Get full text