Search Results - "Migotsky, Nicole"

VEGFA From Early Osteoblast Lineage Cells (Osterix+) Is Required in Mice for Fracture Healing by Buettmann, Evan G, McKenzie, Jennifer A, Migotsky, Nicole, Sykes, David AW, Hu, Pei, Yoneda, Susumu, Silva, Matthew J

“…ABSTRACT Bone formation via intramembranous and endochondral ossification is necessary for successful healing after a wide range of bone injuries. The…”
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Congenital lipodystrophy induces severe osteosclerosis by Zou, Wei, Rohatgi, Nidhi, Brestoff, Jonathan R, Zhang, Yan, Scheller, Erica L, Craft, Clarissa S, Brodt, Michael D, Migotsky, Nicole, Silva, Matthew J, Harris, Charles A, Teitelbaum, Steven L

“…Berardinelli-Seip congenital generalized lipodystrophy is associated with increased bone mass suggesting that fat tissue regulates the skeleton. Because there…”
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Cortical bone relationships are maintained regardless of sex and diet in a large population of LGXSM advanced intercross mice by Migotsky, Nicole, Brodt, Michael D., Cheverud, James M., Silva, Matthew J.

“…Knowledge of bone structure-function relationships in mice has been based on relatively small sample sets that limit generalizability. We sought to investigate…”
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Effect of Genetic Diversity on Cortical Bone Phenotype and Response to Mechanical Loading by Migotsky, Nicole

“…There is a complex interplay between genetics and bone tissue, for both bone morphology and the ability to remodel. Understanding the genetic basis of bone…”
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Osteoblast‐Specific Wnt Secretion Is Required for Skeletal Homeostasis and Loading‐Induced Bone Formation in Adult Mice by Lawson, Lisa Y., Brodt, Michael D., Migotsky, Nicole, Chermside‐Scabbo, Christopher J., Palaniappan, Ramya, Silva, Matthew J.

“…ABSTRACT Wnt signaling is critical to many aspects of skeletal regulation, but the importance of Wnt ligands in the bone anabolic response to mechanical…”
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Type 1 diabetic Akita mice have low bone mass and impaired fracture healing by Hu, Pei, McKenzie, Jennifer A., Buettmann, Evan G., Migotsky, Nicole, Gardner, Michael J., Silva, Matthew J.

“…Type 1 diabetes (T1DM) impairs bone formation and fracture healing in humans. Akita mice carry a mutation in one allele of the insulin-2 (Ins2) gene, which…”
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Activation of hedgehog signaling by systemic agonist improves fracture healing in aged mice by McKenzie, Jennifer A., Maschhoff, Clayton, Liu, Xiaochen, Migotsky, Nicole, Silva, Matthew J., Gardner, Michael J.

“…ABSTRACT Fracture healing is a complex process of many coordinated biological pathways. This system can go awry resulting in nonunion, which leads to…”
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Loading‐induced bone formation is mediated by Wnt1 induction in osteoblast‐lineage cells by Lawson, Lisa Y., Migotsky, Nicole, Chermside‐Scabbo, Christopher J., Shuster, John T., Joeng, Kyu Sang, Civitelli, Roberto, Lee, Brendan, Silva, Matthew J.

“…Mechanical loading on the skeleton stimulates bone formation. Although the exact mechanism underlying this process remains unknown, a growing body of evidence…”
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The effects of NF-κB suppression on the early healing response following intrasynovial tendon repair in a canine model by Lane, Ryan A, Migotsky, Nicole, Havlioglu, Necat, Iannucci, Leanne E, Shen, Hua, Lake, Spencer, Sakiyama-Elbert, Shelly E, Thomopoulos, Stavros, Gelberman, Richard H

“…The highly variable clinical outcomes noted after intrasynovial tendon repair have been associated with an early inflammatory response leading to the…”
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ACTIVATION OF HEDGEHOG SIGNALING BY SYSTEMIC AGONIST IMPROVES FRACTURE HEALING IN AGED MICE by McKenzie, Jennifer A, Maschhoff, Clayton, Liu, Xiaochen, Migotsky, Nicole, Silva, Matthew J, Gardner, Michael J

“…Fracture healing is a complex process of many coordinated biological pathways. This system can go awry resulting in nonunion, which leads to significant…”
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Upper extremity movement reliability and validity of the Kinect version 2 by Reither, Lydia R., Foreman, Matthew H., Migotsky, Nicole, Haddix, Chase, Engsberg, Jack R.

“…Purpose: Studies have shown that marker-less motion detection systems, such as the first generation Kinect (Kinect 1), have good reliability and potential for…”
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Multi-scale cortical bone traits vary in females and males from two mouse models of genetic diversity by Migotsky, Nicole, Kumar, Surabhi, Shuster, John T, Coulombe, Jennifer C, Senwar, Bhavya, Gestos, Adrian A, Farber, Charles R, Ferguson, Virginia L, Silva, Matthew J

“…Understanding the genetic basis of cortical bone traits can allow for the discovery of novel genes or biological pathways regulating bone health. Mice are the…”
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Student Response Initiatives: A Case Study of COVID-19 at Washington University by Chermside-Scabbo, Christopher J., Douglas, Katherine, Ghaznavi, Cyrus, Pollard, Bruin, Abada, Sharon, Goodman, Jared V., Migotsky, Nicole, Park, Kay, Sherburne, Haley, Coolman, Audrey, Aagaard, Eva M., Lawrence, Steven J.

“…The COVID-19 pandemic disrupted medical education worldwide, leading medical students to organize response initiatives. This paper summarizes the Washington…”
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