Search Results - "Mignotte, V."
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Analysis of the thrombopoietin receptor (MPL) promoter implicates GATA and Ets proteins in the coregulation of megakaryocyte-specific genes
Published in Blood (01-06-1996)“…The MPL gene codes for the thrombopoietin receptor, whose ligand specifically controls megakaryocytic differentiation. To understand the molecular basis for…”
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GATA and Ets cis-acting sequences mediate megakaryocyte-specific expression
Published in Molecular and Cellular Biology (01-01-1993)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cis- and Trans-Acting Elements Involved in the Regulation of the Erythroid Promoter of the Human Porphobilinogen Deaminase Gene
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1989)“…Two cis-acting sequences, recognized by two erythroid-specific trans-acting factors, are involved in the regulation of the erythroid promoter of the human gene…”
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The human beta‐globin promoter; nuclear protein factors and erythroid specific induction of transcription
Published in The EMBO journal (20-12-1988)“…We have shown that the promoter of the human beta‐globin gene contains three regions in addition to the known CAC, CAAT and TATA box regions that are important…”
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Structure and transcription of the human c-mpl gene (MPL)
Published in Genomics (San Diego, Calif.) (01-03-1994)“…The human c-mpl proto-oncogene encodes a member of the cytokine receptor superfamily, expressed mainly in CD 34-positive hematopoietic progenitors and in the…”
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Tissue-Specific Splicing Mutation in Acute Intermittent Porphyria
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-1989)“…An inherited deficiency of porphobilinogen deaminase [porphobilinogen ammonia-lyase (polymerizing), EC 4.3.1.8] in humans is responsible for the autosomal…”
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Molecular analysis of acute intermittent porphyria in a Finnish family with normal erythrocyte porphobilinogen deaminase
Published in European journal of clinical investigation (01-10-1989)“…Porphobilinogen deaminase, the third enzyme of the haem biosynthetic pathway, is encoded by two distinct mRNA species expressed in a tissue-specific manner…”
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The extinction of erythroid genes after tetradecanoylphorbol acetate treatment of erythroleukemic cells correlates with down-regulation of the tissue-specific factors NF-E1 and NF-E2
Published in The Journal of biological chemistry (25-12-1990)“…We have studied the elements involved in the tetradecanoylphorbol acetate (TPA)-mediated extinction of erythroid-specific genes. We show that transcription…”
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Regulated expression of the overlapping ubiquitous and erythroid transcription units of the human porphobilinogen deaminase (PBG-D) gene introduced into non-erythroid and erythroid cells
Published in The Journal of biological chemistry (15-06-1989)“…The human gene coding for porphobilinogen deaminase (PBG-D) is transcribed into two distinct transcription units giving two mRNAs. These units originate from…”
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Regulation of embryonic/fetal globin genes by nuclear hormone receptors: a novel perspective on hemoglobin switching
Published in The EMBO journal (01-02-1999)“…The CCAAT box is one of the conserved motifs found in globin promoters. It binds the CP1 protein. We noticed that the CCAAT‐box region of embryonic/fetal, but…”
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Megakaryocytic and erythrocytic lineages share specific transcription factors
Published in Nature (London) (29-03-1990)“…Erythroid-specific genes contain binding sites for NF-E1 (also called GF-1 and Eryf-1; refs 1-3 respectively), the principal DNA-binding protein of the…”
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p45 NF‐E2 regulates expression of thromboxane synthase in megakaryocytes
Published in The EMBO journal (15-09-1997)“…Transcription factor p45 NF‐E2 is highly expressed in the erythroid and megakaryocytic lineages. Although p45 recognizes regulatory regions of several…”
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Macrothrombocytopenia with abnormal demarcation membranes in megakaryocytes and neutropenia with a complete lack of sialyl–Lewis-X antigen in leukocytes—a new syndrome?
Published in Blood (01-02-2001)“…A new megathrombocytopenic syndrome with giant platelets in peripheral blood and severe thrombocytopenia was diagnosed in a 4-month-old boy. His clinical…”
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Two tissue-specific factors bind the erythroid promoter of the human porphobilinogen deaminase gene
Published in Nucleic acids research (11-01-1989)“…We have studied the erythroid-specific promoter of the human gene coding for Porphobilinogen Deaminase (PBGD) by DNaseI footprinting, gel retardation and…”
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Transcriptional Regulation in Megakaryocytes: The Thrombopoietin Receptor Gene as a Model
Published in Stem cells (Dayton, Ohio) (1996)“…The MPL gene codes for the throm‐bopoietin receptor, whose ligand specifically controls megakaryocytic differentiation. In order to understand the molecular…”
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Les doigts de zinc. (2) : les récepteurs hormonaux nucléaires
Published in Hématologie (Montrouge) (1997)Get full text
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De la globine à l'hématopoïèse : compte rendu de la 11e conférence Hemoglobin switching
Published in Hématologie (1999)Get full text
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The dominant control region of the human beta-globin domain
Published in Annals of the New York Academy of Sciences (01-12-1990)Get more information
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