Search Results - "Miglietta, Antonella"

Expression of Cox-2 in human breast cancer cells as a critical determinant of epithelial-to-mesenchymal transition and invasiveness by Bocca, Claudia, Ievolella, Monica, Autelli, Riccardo, Motta, Manuela, Mosso, Luciano, Torchio, Bruno, Bozzo, Francesca, Cannito, Stefania, Paternostro, Claudia, Colombatto, Sebastiano, Parola, Maurizio, Miglietta, Antonella

“…Cyclooxygenase-2 (COX-2) is overexpressed in several malignancies and is implicated in breast cancer progression. We investigated whether changes in COX-2…”
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SerpinB3 Promotes Pro-fibrogenic Responses in Activated Hepatic Stellate Cells by Novo, Erica, Villano, Gianmarco, Turato, Cristian, Cannito, Stefania, Paternostro, Claudia, Busletta, Chiara, Biasiolo, Alessandra, Quarta, Santina, Morello, Elisabetta, Bocca, Claudia, Miglietta, Antonella, David, Ezio, Sutti, Salvatore, Plebani, Mario, Albano, Emanuele, Parola, Maurizio, Pontisso, Patrizia

“…SerpinB3 is a hypoxia- and hypoxia-inducible factor-2α-dependent cystein protease inhibitor that is up-regulated in hepatocellular carcinoma and in parenchymal…”
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Celecoxib inactivates epithelial-mesenchymal transition stimulated by hypoxia and/or epidermal growth factor in colon cancer cells by Bocca, Claudia, Bozzo, Francesca, Cannito, Stefania, Parola, Maurizio, Miglietta, Antonella

“…Celecoxib, a selective cyclooxygenase‐2 (COX‐2) inhibitor, has been reported to exert chemopreventive and antitumor effects on colon cancer, one of the most…”
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Phagocytic uptake of fluorescent stealth and non-stealth solid lipid nanoparticles by Bocca, Claudia, Caputo, Otto, Cavalli, Roberta, Gabriel, Ludovica, Miglietta, Antonella, Gasco, Maria Rosa

“…Fluorescent non-stealth and stealth solid lipid nanoparticles (SLN) were prepared using rhodamine B base as fluorescent marker. The steric stabilization of the…”
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Cellular and molecular mechanisms in liver fibrogenesis by Novo, Erica, Cannito, Stefania, Paternostro, Claudia, Bocca, Claudia, Miglietta, Antonella, Parola, Maurizio

“…•Liver fibrogenesis relies on a heterogeneous population of myofibroblasts (MFs).•Origin of MFs correlates with tissue localization, aetiology and fibrosis…”
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Microtubule-interacting activity and cytotoxicity of the prenylated coumarin ferulenol by Bocca, Claudia, Gabriel, Ludovica, Bozzo, Francesca, Miglietta, Antonella

“…In this study we investigated biological activity of ferulenol, a prenylated 4-hydroxycoumarin from Ferula communis. Ferulenol stimulates tubulin…”
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Angiogenesis and Fibrogenesis in Chronic Liver Diseases by Bocca, Claudia, Novo, Erica, Miglietta, Antonella, Parola, Maurizio

“…Pathologic angiogenesis appears to be intrinsically associated with the fibrogenic progression of chronic liver diseases, which eventually leads to the…”
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Comparative studies on biological activity of certain microtubule-interacting taxanes by Miglietta, Antonella, Bocca, Claudia, Gabriel, Ludovica

“…We have compared the nature of interaction of certain taxanes with microtubular protein, and the mechanism of action underlying cytotoxic activity. Taxanes…”
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Antiproliferative effects of COX-2 inhibitor celecoxib on human breast cancer cell lines by Bocca, Claudia, Bozzo, Francesca, Bassignana, Andrea, Miglietta, Antonella

“…The inducible COX-2 enzyme is over-expressed in human breast cancer and its over-expression generally correlates with angiogenesis, deregulation of apoptosis…”
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COX2 inhibitor NS398 reduces HT-29 cell invasiveness by modulating signaling pathways mediated by EGFR and HIF1-α by Bocca, Claudia, Bozzo, Francesca, Miglietta, Antonella

“…Signals from the tumor microenvironment (hypoxia, growth factors) are known to induce an invasive phenotype. Cyclooxygenase-2 (COX2) overexpression, involved…”
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Hypoxia, hypoxia-inducible factors and fibrogenesis in chronic liver diseases by Cannito, Stefania, Paternostro, Claudia, Busletta, Chiara, Bocca, Claudia, Colombatto, Sebastiano, Miglietta, Antonella, Novo, Erica, Parola, Maurizio

“…Fibrogenic progression of chronic liver diseases (CLDs) towards the end-point of cirrhosis is currently regarded, whatever the aetiology, as a dynamic and…”
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Hepatic myofibroblasts and fibrogenic progression of chronic liver diseases by Novo, Erica, Cannito, Stefania, Morello, Elisabetta, Paternostro, Claudia, Bocca, Claudia, Miglietta, Antonella, Parola, Maurizio

“…Liver fibrogenesis is a dynamic and highly integrated molecular, tissue and cellular process that during the course of a chronic liver disease (CLD) leads…”
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Involvement of PPARγ and E‐cadherin/β‐catenin pathway in the antiproliferative effect of conjugated linoleic acid in MCF‐7 cells by Bocca, Claudia, Bozzo, Francesca, Francica, Simona, Colombatto, Sebastiano, Miglietta, Antonella

“…Conjugated linoleic acid (CLA) is a naturally occurring fatty acid, which has been shown to exert beneficial effects against breast carcinogenesis. It has been…”
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A novel nitro-oxy substituted analogue of rofecoxib reduces human colon cancer cell growth by Bocca, Claudia, Bozzo, Francesca, Ievolella, Monica, Miglietta, Antonella

“…Rofecoxib is a specific COX-2 inhibitor able to exert antiproliferative activity against colorectal cancer cells. It was withdrawn from the market after the…”
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Antiproliferative Effect of a Novel Nitro-oxy Derivative of Celecoxib in Human Colon Cancer Cells: Role of COX-2 and Nitric Oxide by BOCCA, Claudia, BOZZO, Francesca, BASSIGNANA, Andrea, MIGLIETTA, Antonella

“…It has been shown previously that a novel nitrooxy derivative of celecoxib exerts antiproliferative and pro-apoptotic effects in human colon cancer cells. The…”
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Novel nitro-oxy derivatives of celecoxib for the regulation of colon cancer cell growth by Bozzo, Francesca, Bassignana, Andrea, Lazzarato, Loretta, Boschi, Donatella, Gasco, Alberto, Bocca, Claudia, Miglietta, Antonella

“…Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) developed as a selective inhibitor of cyclooxygenase-2 (COX-2). Despite the associated…”
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Involvement of PPARα in the growth inhibitory effect of arachidonic acid on breast cancer cells by Bocca, Claudia, Bozzo, Francesca, Martinasso, Germana, Canuto, Rosa Angela, Miglietta, Antonella

“…Epidemiological studies suggest that dietary PUFA may influence breast cancer progression. n-3 PUFA are generally known to exert antitumour effects, whereas…”
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Angiogenesis and Fibrogenesis in Chronic Liver DiseasesSummary by Claudia Bocca, Erica Novo, Antonella Miglietta, Maurizio Parola

“…Pathologic angiogenesis appears to be intrinsically associated with the fibrogenic progression of chronic liver diseases, which eventually leads to the…”
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COX-2 expression in human breast carcinomas: correlation with clinicopathological features and prognostic molecular markers by Miglietta, Antonella, Toselli, Marina, Ravarino, Nicoletta, Vencia, Walter, Chiecchio, Andrea, Bozzo, Francesca, Motta, Manuela, Torchio, Bruno, Bocca, Claudia

“…COX-2 is implicated in carcinogenesis and tumour progression in many cancers, including breast cancer. Recently, it has been reported that human breast…”
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Antiproliferative effect of conjugated linoleic acid in caco-2 cells: Involvement of PPARγ and APC/β-catenin pathways by Bozzo, Francesca, Bocca, Claudia, Colombatto, Sebastiano, Miglietta, Antonella

“…Conjugated linoleic acid (CLA), a naturally occurring substance in food sources, occurs as mixtures of positional and geometrical isomers of octadecadienoate…”
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