Search Results - "Mietzner, T. A"

Evaluation of WLBU2 Peptide and 3-O-Octyl-sn-Glycerol Lipid as Active Ingredients for a Topical Microbicide Formulation Targeting Chlamydia trachomatis by SKINNER, M. C, KISELEV, A. O, ISAACS, C. E, MIETZNER, T. A, MONTELARO, R. C, LAMPE, M. F

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Sulfate as a Synergistic Anion Facilitating Iron Binding by the Bacterial Transferrin FbpA:  The Origins and Effects of Anion Promiscuity by Heymann, J. J, Weaver, K. D, Mietzner, T. A, Crumbliss, A. L

“…The ferric binding protein, FbpA, has been demonstrated to facilitate the transport of naked Fe3+ across the periplasmic space of several Gram-negative…”
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role of iron-binding proteins in the survival of pathogenic bacteria by Meitzner, T.A, Morse, S.A

“…This review covers the role of iron-binding proteins in the pathogenesis of infectious disease and host iron-binding proteins as the reservoir of iron for…”
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Novel antimicrobial peptides derived from human immunodeficiency virus type 1 and other lentivirus transmembrane proteins by TENCZA, S. B, DOUGLASS, J. P, CREIGHTON, D. J, MONTELARO, R. C, MIETZNER, T. A

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Lentivirus-derived antimicrobial peptides : increased potency by sequence engineering and dimerization by TENCZA, S. B, CREIGHTON, D. J, TAO YUAN, VOGEL, H. J, MONTELARO, R. C, MIETZNER, T. A

“…We have previously described a family of cationic amphipathic peptides derived from lentivirus envelope proteins that have properties similar to those of…”
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The fbpABC locus of Neisseria gonorrhoeae functions in the periplasm-to-cytosol transport of iron by Adhikari, P, Berish, S A, Nowalk, A J, Veraldi, K L, Morse, S A, Mietzner, T A

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Mapping of functional regions of Clostridium perfringens type A enterotoxin by HANNA, WIECKOWSKI, E. U, MIETZNER, T. A, MCCLANE, B. A

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Localization of the receptor-binding region of Clostridium perfringens enterotoxin utilizing cloned toxin fragments and synthetic peptides. The 30 C-terminal amino acids define a functional binding region by HANNA, P. C, MIETZNER, T. A, SCHOOLNIK, G. K, MCCLANE, B. A

“…In this study a short sequence encoding the receptor-binding activity of the much larger 35-kDa enterotoxin elaborated by Clostridium perfringens was localized…”
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Calmodulin-binding function of LLP segments from the HIV type 1 transmembrane protein is conserved among natural sequence variants by Tencza, S B, Mietzner, T A, Montelaro, R C

“…LLP1 is a peptide, derived from the cytoplasmic tail of HIV-1 TM glycoprotein, that binds and inhibits calmodulin; this region is generally conserved among…”
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The ferric iron-binding protein of pathogenic Neisseria spp. functions as a periplasmic transport protein in iron acquisition from human transferrin by Chen, C Y, Berish, S A, Morse, S A, Mietzner, T A

“…The ferric iron-binding protein (Fbp) expressed by pathogenic Neisseria spp. has been proposed to play a central role in the high-affinity acquisition of iron…”
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Alterations in cell membrane permeability by the lentivirus lytic peptide (LLP-1) of HIV-1 transmembrane protein by Miller, M A, Cloyd, M W, Liebmann, J, Rinaldo, Jr, C R, Islam, K R, Wang, S Z, Mietzner, T A, Montelaro, R C

“…Previously we reported that synthetic peptide homologs of an amphipathic region (designated the lentivirus lytic peptide, or LLP-1) near the carboxy terminus…”
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Effect of amino acid substitutions on calmodulin binding and cytolytic properties of the LLP-1 peptide segment of human immunodeficiency virus type 1 transmembrane protein by Tencza, S B, Miller, M A, Islam, K, Mietzner, T A, Montelaro, R C

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A conjugated synthetic peptide corresponding to the C-terminal region of Clostridium perfringens type A enterotoxin elicits an enterotoxin-neutralizing antibody response in mice by Mietzner, T.A. (University of Pittsburgh School of Medicine, Pittsburgh, PA), Kokai-Kun, J.F, Hanna, P.C, McClane, B.A

“…A synthetic peptide homolog corresponding to the C-terminal 30 amino acids of Clostridium perfringens type A enterotoxin (CPE) was conjugated to a…”
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A synthetic peptide corresponding to the carboxy terminus of human immunodeficiency virus type 1 transmembrane glycoprotein induces alterations in the ionic permeability of Xenopus laevis oocytes by Comardelle, A M, Norris, C H, Plymale, D R, Gatti, P J, Choi, B, Fermin, C D, Haislip, A M, Tencza, S B, Mietzner, T A, Montelaro, R C, Garry, R F

“…The carboxy-terminal 29 amino acids of the human immunodeficiency virus type 1 transmembrane glycoprotein (HIV-1 TM) are referred to as lentivirus lytic…”
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Identification of an iron-regulated 37,000-dalton protein in the cell envelope of Neisseria gonorrhoeae by MIETZNER, T. A, LUGINBUHL, G. H, SANDSTROM, E, MORSE, S. A

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The Influence of the Synergistic Anion on Iron Chelation by Ferric Binding Protein, a Bacterial Transferrin by Dhungana, Suraj, Taboy, Céline H., Anderson, Damon S., Vaughan, Kevin G., Aisen, Philip, Mietzner, Timothy A., Crumbliss, Alvin L.

“…Although the presence of an exogenous anion is a requirement for tight Fe3+ binding by the bacterial (Neisseria) transferrin nFbp, the identity of the…”
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The pili of aeromonas hydrophila : identification of an environmentally regulated mini pilin by SUK YUE HO, A, MIETZNER, T. A, SMITH, A. J, SCHOOLNIK, G. K

“…Ultrastructural studies of Aeromonas hydrophila strain AH26 revealed two distinctive pilus types: "straight" pili appear as brittle, rod-like filaments,…”
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Peptide Antisera as Sequence-Specific Probes of Protein Conformational Transitions: Calmodulin Exhibits Calcium-Dependent Changes in Antigenicity by Gariépy, Jean, Mietzner, Timothy A., Schoolnik, Gary K.

“…Local changes in conformation between the calcium-saturated and calcium-free forms of calmodulin were monitored using antisera to four peptides corresponding…”
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Molecular cloning and characterization of the structural gene for the major iron-regulated protein expressed by Neisseria gonorrhoeae by BERISH, S. A, MIETZNER, T. A, MAYER, L. W, GENCO, C. A, HOLLOWAY, B. P, MORSE, S. A

“…This report describes the cloning and sequencing of the major iron-regulated protein (termed Fbp) of Neisseria gonorrhoeae strain F62. Attempts to identify…”
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Fe3+ Coordination and Redox Properties of a Bacterial Transferrin by Taboy, Céline H., Vaughan, Kevin G., Mietzner, Timothy A., Aisen, Philip, Crumbliss, Alvin L.

“…The Fe3+ binding site of recombinant nFbp, a ferric-binding protein found in the periplasmic space of pathogenic Neisseria, has been characterized by…”
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