Search Results - "Mieszawska, Aneta J."

Multifunctional Gold Nanoparticles for Diagnosis and Therapy of Disease by Mieszawska, Aneta J, Mulder, Willem J. M, Fayad, Zahi A, Cormode, David P

“…Gold nanoparticles (AuNPs) have a number of physical properties that make them appealing for medical applications. For example, the attenuation of X-rays by…”
Get full text

A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation by Duivenvoorden, Raphaël, Tang, Jun, Cormode, David P., Mieszawska, Aneta J., Izquierdo-Garcia, David, Ozcan, Canturk, Otten, Maarten J., Zaidi, Neeha, Lobatto, Mark E., van Rijs, Sarian M., Priem, Bram, Kuan, Emma L., Martel, Catherine, Hewing, Bernd, Sager, Hendrik, Nahrendorf, Matthias, Randolph, Gwendalyn J., Stroes, Erik S. G., Fuster, Valentin, Fisher, Edward A., Fayad, Zahi A., Mulder, Willem J. M.

“…Inflammation is a key feature of atherosclerosis and a target for therapy. Statins have potent anti-inflammatory properties but these cannot be fully exploited…”
Get full text

The Synthesis and Fabrication of One-Dimensional Nanoscale Heterojunctions by Mieszawska, Aneta J., Jalilian, Romaneh, Sumanasekera, Gamini U., Zamborini, Francis P.

“…There are a variety of methods for synthesizing or fabricating one‐dimensional (1D) nanostructures containing heterojunctions between different materials. Here…”
Get full text

Probing nanoparticle translocation across the permeable endothelium in experimental atherosclerosis by Kim, YongTae, Lobatto, Mark E., Kawahara, Tomohiro, Chung, Bomy Lee, Mieszawska, Aneta J., Sanchez-Gaytan, Brenda L., Fay, Francois, Senders, Max L., Calcagno, Claudia, Becraft, Jacob, Saung, May Tun, Gordon, Ronald E., Stroes, Erik S. G., Ma, Mingming, Farokhzad, Omid C., Fayad, Zahi A., Mulder, Willem J. M., Langer, Robert

“…Therapeutic and diagnostic nanomaterials are being intensely studied for several diseases, including cancer and atherosclerosis. However, the exact mechanism…”
Get full text

Synthesis of Polymer–Lipid Nanoparticles for Image-Guided Delivery of Dual Modality Therapy by Mieszawska, Aneta J, Kim, YongTae, Gianella, Anita, van Rooy, Inge, Priem, Bram, Labarre, Matthew P, Ozcan, Canturk, Cormode, David P, Petrov, Artiom, Langer, Robert, Farokhzad, Omid C, Fayad, Zahi A, Mulder, Willem J. M

“…For advanced treatment of diseases such as cancer, multicomponent, multifunctional nanoparticles hold great promise. In the current study we report the…”
Get full text

Smart biomaterials - regulating cell behavior through signaling molecules by Mieszawska, Aneta J, Kaplan, David L

“…Important advances in the field of tissue engineering are arising from increased interest in novel biomaterial designs with bioactive components that directly…”
Get full text

Nano-Based Systems and Biomacromolecules as Carriers for Metallodrugs in Anticancer Therapy by Poursharifi, Mina, Wlodarczyk, Marek T., Mieszawska, Aneta J.

“…Since the discovery of cisplatin and its potency in anticancer therapy, the development of metallodrugs has been an active area of research. The large choice…”
Get full text

Pt(II)-PLGA Hybrid in a pH-Responsive Nanoparticle System Targeting Ovarian Cancer by Wlodarczyk, Marek T, Dragulska, Sylwia A, Chen, Ying, Poursharifi, Mina, Acosta Santiago, Maxier, Martignetti, John A, Mieszawska, Aneta J

“…Platinum-based agents are the main treatment option in ovarian cancer (OC). Herein, we report a poly(lactic-co-glycolic acid) (PLGA) nanoparticle (NP)…”
Get full text

Inorganic nanocrystals as contrast agents in MRI: synthesis, coating and introduction of multifunctionality by Cormode, David P., Sanchez-Gaytan, Brenda L., Mieszawska, Aneta J., Fayad, Zahi A., Mulder, Willem J. M.

“…Inorganic nanocrystals have myriad applications in medicine, including their use as drug or gene delivery complexes, therapeutic hyperthermia agents, in…”
Get full text

Synthesis and Manipulation of High Aspect Ratio Gold Nanorods Grown Directly on Surfaces by Wei, Zhongqing, Mieszawska, Aneta J, Zamborini, Francis P

“…Here we describe the synthesis of Au nanorods directly on glass surfaces using seed-mediated deposition of Au from AuCl4 - onto surface-attached 3−5 nm…”
Get full text

Directing the Growth of Highly Aligned Gold Nanorods through a Surface Chemical Amidation Reaction by Mieszawska, Aneta J, Slawinski, Grzegorz W, Zamborini, Francis P

“…This paper describes the seed-mediated growth of highly aligned gold nanorods (Au NRs) over large areas directly on a Si(100) surface. The Si(100) surface is…”
Get full text

Synthesis of Gold Nanorod/Single-Wall Carbon Nanotube Heterojunctions Directly on Surfaces by Mieszawska, Aneta J, Jalilian, Romaneh, Sumanasekera, Gamini U, Zamborini, Francis P

“…This contribution describes the synthesis of gold nanorod (Au NR)/single-wall carbon nanotube (SWCNT) heterojunctions assembled directly on Si/SiO x…”
Get full text

Silk-Based Nanocomplexes with Tumor-Homing Peptides for Tumor-Specific Gene Delivery by Numata, Keiji, Mieszawska-Czajkowska, Aneta J., Kvenvold, Laura A., Kaplan, David L.

“…Nanoscale complexes of recombinant silk molecules containing THPs with DNA are designed as less cytotoxic and highly target‐specific gene carriers. Genetically…”
Get full text

Engineering and Validation of a Peptide-Stabilized Poly(lactic-co-glycolic) Acid Nanoparticle for Targeted Delivery of a Vascular Disruptive Agent in Cancer Therapy by Dragulska, Sylwia A., Poursharifi, Mina, Chen, Ying, Wlodarczyk, Marek T., Acosta Santiago, Maxier, Dottino, Peter, Martignetti, John A., Mieszawska, Aneta J.

“…Developing a biocompatible and biodegradable nanoparticle (NP) carrier that integrates drug-loading capability, active targeting, and imaging modality is…”
Get full text

Osteoinductive silk–silica composite biomaterials for bone regeneration by Mieszawska, Aneta J, Fourligas, Nikolaos, Georgakoudi, Irene, Ouhib, Nadia M, Belton, David J, Perry, Carole C, Kaplan, David L

“…Abstract Osteoinductive and biodegradable composite biomaterials for bone regeneration were prepared by combining silk fibroin with silica particles. The…”
Get full text

Nanoscale Control of Silica Particle Formation via Silk−Silica Fusion Proteins for Bone Regeneration by Mieszawska, Aneta J, Nadkarni, Lauren D, Perry, Carole C, Kaplan, David L

“…The biomimetic design of silk/silica fusion proteins was carried out, combining the self-assembling domains of spider dragline silk (Nephila clavipes) and the…”
Get full text

Tripeptide-Stabilized Oil-in-Water Nanoemulsion of an Oleic Acids–Platinum(II) Conjugate as an Anticancer Nanomedicine by Dragulska, Sylwia A, Chen, Ying, Wlodarczyk, Marek T, Poursharifi, Mina, Dottino, Peter, Ulijn, Rein V, Martignetti, John A, Mieszawska, Aneta J

“…We report a nanoemulsion (NE) which is stabilized by self-assembling tripeptide lysine-tyrosine-phenylalanine (KYF) and encapsulates an oleic acids–platinum…”
Get full text

Clay enriched silk biomaterials for bone formation by Mieszawska, Aneta J., Llamas, Jabier Gallego, Vaiana, Christopher A., Kadakia, Madhavi P., Naik, Rajesh R., Kaplan, David L.

“…The formation of silk protein/clay composite biomaterials for bone tissue formation is described. Silk fibroin serves as an organic scaffolding material…”
Get full text

Engineering of lipid-coated PLGA nanoparticles with a tunable payload of diagnostically active nanocrystals for medical imaging by Mieszawska, Aneta J, Gianella, Anita, Cormode, David P, Zhao, Yiming, Meijerink, Andries, Langer, Robert, Farokhzad, Omid C, Fayad, Zahi A, Mulder, Willem J M

“…Polylactic-co-glycolic acid (PLGA) based nanoparticles are biocompatible and biodegradable and therefore have been extensively investigated as therapeutic…”
Get more information

Gold Nanocrystal Labeling Allows Low-Density Lipoprotein Imaging from the Subcellular to Macroscopic Level by Allijn, Iris E, Leong, Wei, Tang, Jun, Gianella, Anita, Mieszawska, Aneta J, Fay, Francois, Ma, Ge, Russell, Stewart, Callo, Catherine B, Gordon, Ronald E, Korkmaz, Emine, Post, Jan Andries, Zhao, Yiming, Gerritsen, Hans C, Thran, Axel, Proksa, Roland, Daerr, Heiner, Storm, Gert, Fuster, Valentin, Fisher, Edward A, Fayad, Zahi A, Mulder, Willem J. M, Cormode, David P

“…Low-density lipoprotein (LDL) plays a critical role in cholesterol transport and is closely linked to the progression of several diseases. This motivates the…”
Get full text