Search Results - "Miesfeld, Roger L."

Identification and characterization of a mosquito-specific eggshell organizing factor in Aedes aegypti mosquitoes by Isoe, Jun, Koch, Lauren E, Isoe, Yurika E, Rascón, Jr, Alberto A, Brown, Heidi E, Massani, Brooke B, Miesfeld, Roger L

“…Mosquito-borne diseases are responsible for several million human deaths annually around the world. One approach to controlling mosquito populations is to…”
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Characterization of essential eggshell proteins from Aedes aegypti mosquitoes by Isoe, Jun, Simington, Carter J, Oscherwitz, Max E, Peterson, Alyssa J, Rascón, Alberto A, Massani, Brooke B, Miesfeld, Roger L, Riehle, Michael A

“…Up to 40% of the world population live in areas where mosquitoes capable of transmitting the dengue virus, including Aedes aegypti, coexist with humans…”
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Defects in coatomer protein I (COPI) transport cause blood feeding-induced mortality in Yellow Fever mosquitoes by Isoe, Jun, Collins, Jennifer, Badgandi, Hemant, Day, W. Anthony, Miesfeld, Roger L

“…Blood feeding by vector mosquitoes provides the entry point for disease pathogens and presents an acute metabolic challenge that must be overcome to complete…”
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Alpha-COPI coatomer protein is required for rough endoplasmic reticulum whorl formation in mosquito midgut epithelial cells by Zhou, Guoli, Isoe, Jun, Day, W Antony, Miesfeld, Roger L

“…One of the early events in midgut epithelial cells of Aedes aegypti mosquitoes is the dynamic reorganization of rough endoplasmic reticulum (RER) whorl…”
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Discovery of an alternate metabolic pathway for urea synthesis in adult Aedes aegypti mosquitoes by Scaraffia, Patricia Y, Tan, Guanhong, Isoe, Jun, Wysocki, Vicki H, Wells, Michael A, Miesfeld, Roger L

“…We demonstrate the presence of an alternate metabolic pathway for urea synthesis in Aedes aegypti mosquitoes that converts uric acid to urea via an…”
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Deficiencies in acetyl-CoA carboxylase and fatty acid synthase 1 differentially affect eggshell formation and blood meal digestion in Aedes aegypti by Alabaster, Amy, Isoe, Jun, Zhou, Guoli, Lee, Ada, Murphy, Ashleigh, Day, W. Anthony, Miesfeld, Roger L

“…To better understand the mechanism of de novo lipid biosynthesis in blood fed Aedes aegypti mosquitoes, we quantitated acetyl-CoA carboxylase (ACC) and fatty…”
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Energy metabolism during diapause in Culex pipiens mosquitoes by Zhou, Guoli, Miesfeld, Roger L.

“…Diapause in overwintering adult female Culex pipiens mosquitoes plays an important role in the transmission of West Nile and other encephalitis-inducing…”
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COPI-mediated blood meal digestion in vector mosquitoes is independent of midgut ARF-GEF and ARF-GAP regulatory activities by Isoe, Jun, Stover, Weston, Miesfeld, R. Barrett, Miesfeld, Roger L.

“…We have previously shown that defects in COPI coatomer proteins cause 80% mortality in blood fed Aedes aegypti mosquitoes by 96 h post-feeding. In this study…”
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Molecular genetic analysis of midgut serine proteases in Aedes aegypti mosquitoes by Isoe, Jun, Rascón, Alberto A., Kunz, Susan, Miesfeld, Roger L.

“…Digestion of blood meal proteins by midgut proteases provides anautogenous mosquitoes with the nutrients required to complete the gonotrophic cycle. Inhibition…”
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Differential ammonia metabolism in Aedes aegypti fat body and midgut tissues by Scaraffia, Patricia Y., Zhang, Qingfen, Thorson, Kelsey, Wysocki, Vicki H., Miesfeld, Roger L.

“…In order to understand at the tissue level how Aedes aegypti copes with toxic ammonia concentrations that result from the rapid metabolism of blood meal…”
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Molecular analysis of the Aedes aegypti carboxypeptidase gene family by Isoe, Jun, Zamora, Jorge, Miesfeld, Roger L.

“…To gain a better understanding of coordinate regulation of protease gene expression in the mosquito midgut, we undertook a comprehensive molecular study of…”
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Distinct biological effects of golgicide a derivatives on larval and adult mosquitoes by Mack, Daniel J., Isoe, Jun, Miesfeld, Roger L., Njardarson, Jon T.

“…A collection of Golgicide A (GCA) analogs has been synthesized and evaluated in larval and adult mosquito assays. Commercially available GCA is a mixture of…”
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Expression profiling and comparative analyses of seven midgut serine proteases from the yellow fever mosquito, Aedes aegypti by Brackney, Doug E., Isoe, Jun, W.C., Black, Zamora, Jorge, Foy, Brian D., Miesfeld, Roger L., Olson, Ken E.

“…Aedes aegypti utilizes blood for energy production, egg maturation and replenishment of maternal reserves. The principle midgut enzymes responsible for…”
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Differentiation and quantification of C1 and C2 (13)C-labeled glucose by tandem mass spectrometry by Jiang, Wei, Wysocki, Vicki H, Dodds, Eric D, Miesfeld, Roger L, Scaraffia, Patricia Y

“…The fragmentation patterns of various (13)C-labeled glucose molecules were analyzed by electrospray ionization tandem mass spectrometry. Derivatization of…”
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TOR signaling is required for amino acid stimulation of early trypsin protein synthesis in the midgut of Aedes aegypti mosquitoes by Brandon, Michelle C., Pennington, James E., Isoe, Jun, Zamora, Jorge, Schillinger, Anne-Sophie, Miesfeld, Roger L.

“…Blood meal digestion in mosquitoes occurs in two phases, an early phase that is translationally regulated, and a late phase that is transcriptionally…”
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The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function by Chamberlain, Nancy L., Driver, Erika D., Miesfeld, Roger L.

“…Some transcription factors contain stretches of polyglutamine encoded by repeats of the trinucleotide CAG. Expansion of the CAG repeat in the androgen receptor…”
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In vitro activation and enzyme kinetic analysis of recombinant midgut serine proteases from the Dengue vector mosquito Aedes aegypti by Rascón, Jr, Alberto A, Gearin, Johnathon, Isoe, Jun, Miesfeld, Roger L

“…The major Dengue virus vector Aedes aegypti requires nutrients obtained from blood meal proteins to complete the gonotrophic cycle. Although bioinformatic…”
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Increased expression of the metastasis-associated gene Ehm2 in prostate cancer by Wang, Jianghua, Cai, Yi, Penland, Rebecca, Chauhan, Sanjay, Miesfeld, Roger L., Ittmann, Michael

“…BACKGROUND Alterations of fibroblast growth factors and their receptors contribute to prostate cancer progression by enhancing cell survival, motility, and…”
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Delineation of Two Distinct Type 1 Activation Functions in the Androgen Receptor Amino-terminal Domain by Chamberlain, N L, Whitacre, D C, Miesfeld, R L

“…Based on the finding that some transcription factors contain multiple transcriptional regulatory activities, we constructed a panel of rat androgen receptor…”
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Androgen control of cell proliferation and cytoskeletal reorganization in human fibrosarcoma cells: role of RhoB signaling by Chauhan, Sanjay, Kunz, Susan, Davis, Kelli, Roberts, Jordan, Martin, Greg, Demetriou, Manolis C, Sroka, Thomas C, Cress, Anne E, Miesfeld, Roger L

“…We recently generated an HT-1080-derived cell line called HT-AR1 that responds to dihydrotestosterone (DHT) treatment by undergoing cell growth arrest in…”
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