Search Results - "Miesfeld, Joel"

Yap and Taz regulate retinal pigment epithelial cell fate by Miesfeld, Joel B, Gestri, Gaia, Clark, Brian S, Flinn, Michael A, Poole, Richard J, Bader, Jason R, Besharse, Joseph C, Wilson, Stephen W, Link, Brian A

“…The optic vesicle comprises a pool of bi-potential progenitor cells from which the retinal pigment epithelium (RPE) and neural retina fates segregate during…”
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Eye organogenesis: A hierarchical view of ocular development by Miesfeld, Joel B, Brown, Nadean L

“…This chapter provides an overview of the early developmental origins of six ocular tissues: the cornea, lens, ciliary body, iris, neural retina, and retina…”
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YAP is essential for tissue tension to ensure vertebrate 3D body shape by Porazinski, Sean, Wang, Huijia, Asaoka, Yoichi, Behrndt, Martin, Miyamoto, Tatsuo, Morita, Hitoshi, Hata, Shoji, Sasaki, Takashi, Krens, S. F. Gabriel, Osada, Yumi, Asaka, Satoshi, Momoi, Akihiro, Linton, Sarah, Miesfeld, Joel B., Link, Brian A., Senga, Takeshi, Castillo-Morales, Atahualpa, Urrutia, Araxi O., Shimizu, Nobuyoshi, Nagase, Hideaki, Matsuura, Shinya, Bagby, Stefan, Kondoh, Hisato, Nishina, Hiroshi, Heisenberg, Carl-Philipp, Furutani-Seiki, Makoto

“…D’Arcy Thompson predicted a century ago that animal body shape is conditioned by gravity, but there has been no animal model to study how cellular forces are…”
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The Atoh7 remote enhancer provides transcriptional robustness during retinal ganglion cell development by Miesfeld, Joel B., Ghiasvand, Noor M., Marsh-Armstrong, Brennan, Marsh-Armstrong, Nicholas, Miller, Eric B., Zhang, Pengfei, Manna, Suman K., Zawadzki, Robert J., Brown, Nadean L., Glaser, Tom

“…The retinal ganglion cell (RGC) competence factor ATOH7 is dynamically expressed during retinal histogenesis. ATOH7 transcription is controlled by a…”
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The dynamics of native Atoh7 protein expression during mouse retinal histogenesis, revealed with a new antibody by Miesfeld, Joel B., Glaser, Tom, Brown, Nadean L.

“…The Atoh7 transcription factor catalyzes the rate-limiting step in the specification of retinal ganglion cells (RGCs). As a tool to study vertebrate retinal…”
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Loss of Llgl1 in retinal neuroepithelia reveals links between apical domain size, Notch activity and neurogenesis by Clark, Brian S, Cui, Shuang, Miesfeld, Joel B, Klezovitch, Olga, Vasioukhin, Valeri, Link, Brian A

“…To gain insights into the cellular mechanisms of neurogenesis, we analyzed retinal neuroepithelia deficient for Llgl1, a protein implicated in apicobasal cell…”
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Feedback between tissue packing and neurogenesis in the zebrafish neural tube by Hiscock, Tom W, Miesfeld, Joel B, Mosaliganti, Kishore R, Link, Brian A, Megason, Sean G

“…Balancing the rate of differentiation and proliferation in developing tissues is essential to produce organs of robust size and composition. Although many…”
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The rax homeobox gene is mutated in the eyeless axolotl, Ambystoma mexicanum by Davis, Erik S., Voss, Gareth, Miesfeld, Joel B., Zarate‐Sanchez, Juan, Voss, S. Randal, Glaser, Tom

“…Background Vertebrate eye formation requires coordinated inductive interactions between different embryonic tissue layers, first described in amphibians. A…”
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Rbpj direct regulation of Atoh7 transcription in the embryonic mouse retina by Miesfeld, Joel B., Moon, Myung-soon, Riesenberg, Amy N., Contreras, Ashley N., Kovall, Rhett A., Brown, Nadean L.

“…In vertebrate retinal progenitor cells, the proneural factor Atoh7 exhibits a dynamic tissue and cellular expression pattern. Although the resulting Atoh7…”
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Dynamic Polarization of Rab11a Modulates Crb2a Localization and Impacts Signaling to Regulate Retinal Neurogenesis by Clark, Brian S, Miesfeld, Joel B, Flinn, Michael A, Collery, Ross F, Link, Brian A

“…Interkinetic nuclear migration (IKNM) is the process in which pseudostratified epithelial nuclei oscillate from the apical to basal surface and in phase with…”
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Loss of Llgl1 results in neuroepithelial apical domain expansion, increased Notch activity and reduced neurogenesis in the zebrafish retina by Clark, Brian, Cui, Shuang, Miesfeld, Joel B., Link, Brian A.

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Establishment of transgenic lines that report nervous system specific Notch activity based on nort gene regulatory sequence by Miesfeld, Joel B., Clark, Brian S., Link, Brian A.

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Establishment of transgenic lines to monitor and manipulate Yap/Taz-Tead activity in zebrafish reveals both evolutionarily conserved and divergent functions of the Hippo pathway by Miesfeld, Joel B., Link, Brian A.

“…•Transgenic fish were generated to report and manipulate Hippo signaling.•Loss of Yap/Taz activity resulted in cardiac progenitor migration defects.•Loss of…”
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Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth by Cox, Andrew G, Tsomides, Allison, Yimlamai, Dean, Hwang, Katie L, Miesfeld, Joel, Galli, Giorgio G, Fowl, Brendan H, Fort, Michael, Ma, Kimberly Y, Sullivan, Mark R, Hosios, Aaron M, Snay, Erin, Yuan, Min, Brown, Kristin K, Lien, Evan C, Chhangawala, Sagar, Steinhauser, Matthew L, Asara, John M, Houvras, Yariv, Link, Brian, Vander Heiden, Matthew G, Camargo, Fernando D, Goessling, Wolfram

“…The Hippo pathway and its nuclear effector Yap regulate organ size and cancer formation. While many modulators of Hippo activity have been identified, little…”
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Yap and Taz regulate retinal pigment epithelial cell fate by Miesfeld, Joel B., Gestri, Gaia, Clark, Brian S., Flinn, Michael A., Poole, Richard J., Bader, Jason R., Besharse, Joseph C., Wilson, Stephen W., Link, Brian A.

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Analysis of Yap/Taz-Tead Signaling During Zebrafish Ocular Development by Miesfeld, Joel Bryan

“…Disruption of proper eye development can lead to the presence of eye malformations or visual defects present at birth. Due to in utero development of humans,…”
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