Search Results - "Mierke, Claudia"

The phenotype of cancer cell invasion controlled by fibril diameter and pore size of 3D collagen networks by Sapudom, Jiranuwat, Rubner, Stefan, Martin, Steve, Kurth, Tony, Riedel, Stefanie, Mierke, Claudia T, Pompe, Tilo

“…Abstract The behavior of cancer cells is strongly influenced by the properties of extracellular microenvironments, including topology, mechanics and…”
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Magnetically Guided Titania Nanotubes for Site-Selective Photocatalysis and Drug Release by Shrestha, Nabeen K, Macak, Jan M, Schmidt-Stein, Felix, Hahn, Robert, Mierke, Claudia T, Fabry, Ben, Schmuki, Patrik

“…Quick release: The spatial and temporal delivery of active molecules (dyes or drugs) can be precisely controlled by the photocatalytic activity of TiO2…”
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Focal adhesion kinase activity is required for actomyosin contractility-based invasion of cells into dense 3D matrices by Mierke, Claudia T., Fischer, Tony, Puder, Stefanie, Kunschmann, Tom, Soetje, Birga, Ziegler, Wolfgang H.

“…The focal adhesion kinase (FAK) regulates the dynamics of integrin-based cell adhesions important for motility. FAK’s activity regulation is involved in…”
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The role of the tissue microenvironment in the regulation of cancer cell motility and invasion by Brábek, Jan, Mierke, Claudia T, Rösel, Daniel, Veselý, Pavel, Fabry, Ben

“…During malignant neoplastic progression the cells undergo genetic and epigenetic cancer-specific alterations that finally lead to a loss of tissue homeostasis…”
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Physical break-down of the classical view on cancer cell invasion and metastasis by Mierke, Claudia T.

“…Eight classical hallmarks of cancer have been proposed and are well-defined by using biochemical or molecular genetic methods, but are not yet precisely…”
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Cancer Cells Regulate Biomechanical Properties of Human Microvascular Endothelial Cells by Mierke, Claudia Tanja

“…Metastasis is a key event of malignant tumor progression. The capability to metastasize depends on the ability of the cancer cell to migrate into connective…”
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Mechanical Cues Affect Migration and Invasion of Cells From Three Different Directions by Mierke, Claudia Tanja

“…Cell migration and invasion is a key driving factor for providing essential cellular functions under physiological conditions or the malignant progression of…”
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Vinculin Facilitates Cell Invasion into Three-dimensional Collagen Matrices by Mierke, Claudia T., Kollmannsberger, Philip, Zitterbart, Daniel Paranhos, Diez, Gerold, Koch, Thorsten M., Marg, Susanna, Ziegler, Wolfgang H., Goldmann, Wolfgang H., Fabry, Ben

“…The cytoskeletal protein vinculin contributes to the mechanical link of the contractile actomyosin cytoskeleton to the extracellular matrix (ECM) through…”
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Viscoelasticity, Like Forces, Plays a Role in Mechanotransduction by Mierke, Claudia Tanja

“…Viscoelasticity and its alteration in time and space has turned out to act as a key element in fundamental biological processes in living systems, such as…”
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Endothelial cell's biomechanical properties are regulated by invasive cancer cells by Mierke, Claudia T

“…Most cancer-related deaths are caused by the ability of cancer cells to metastasize. This process includes the dissemination of cancer cells from the primary…”
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Viscoelasticity Acts as a Marker for Tumor Extracellular Matrix Characteristics by Mierke, Claudia Tanja

“…Biological materials such as extracellular matrix scaffolds, cancer cells, and tissues are often assumed to respond elastically for simplicity; the…”
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Phenotypic Heterogeneity, Bidirectionality, Universal Cues, Plasticity, Mechanics, and the Tumor Microenvironment Drive Cancer Metastasis by Mierke, Claudia Tanja

“…Tumor diseases become a huge problem when they embark on a path that advances to malignancy, such as the process of metastasis. Cancer metastasis has been…”
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Extracellular Matrix Cues Regulate Mechanosensing and Mechanotransduction of Cancer Cells by Mierke, Claudia Tanja

“…Extracellular biophysical properties have particular implications for a wide spectrum of cellular behaviors and functions, including growth, motility,…”
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Phagocytized Beads Reduce the alpha 5 beta 1 Integrin Facilitated Invasiveness of Cancer Cells by Regulating Cellular Stiffness by Mierke, Claudia T

“…Cell invasion through the extracellular matrix (ECM) of connective tissue is an important biomechanical process, which plays a prominent role in tumor…”
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CD24 controls Src/STAT3 activity in human tumors by Bretz, Niko P., Salnikov, Alexei V., Perne, Claudia, Keller, Sascha, Wang, Xiaoli, Mierke, Claudia T., Fogel, Mina, Erbe-Hofmann, Natalie, Schlange, Thomas, Moldenhauer, Gerhard, Altevogt, Peter

“…CD24 is a glycosyl-phosphatidylinositol-anchored membrane protein that is frequently over-expressed in a variety of human carcinomas and is correlated with…”
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Bioprinting of Cells, Organoids and Organs-on-a-Chip Together with Hydrogels Improves Structural and Mechanical Cues by Mierke, Claudia Tanja

“…The 3D bioprinting technique has made enormous progress in tissue engineering, regenerative medicine and research into diseases such as cancer. Apart from…”
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The versatile roles of ADAM8 in cancer cell migration, mechanics, and extracellular matrix remodeling by Mierke, Claudia Tanja

“…The posttranslational proteolytic cleavage is a unique and irreversible process that governs the function and half-life of numerous proteins. Thereby the role…”
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Mechanosensory entities and functionality of endothelial cells by Mierke, Claudia Tanja

“…The endothelial cells of the blood circulation are exposed to hemodynamic forces, such as cyclic strain, hydrostatic forces, and shear stress caused by the…”
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The Biomechanical Properties of 3d Extracellular Matrices and Embedded Cells Regulate the Invasiveness of Cancer Cells by Mierke, Claudia T.

“…The malignancy of tumors depends on the biomechanical properties of cancer cells and their microenvironment, which enable cancer cells to migrate through the…”
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Phagocytized Beads Reduce the α5β1 Integrin Facilitated Invasiveness of Cancer Cells by Regulating Cellular Stiffness by Mierke, Claudia T.

“…Cell invasion through the extracellular matrix (ECM) of connective tissue is an important biomechanical process, which plays a prominent role in tumor…”
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