Search Results - "Mienda, Bashir Sajo"

Escherichia coli Genome-scale metabolic models could guide construction of proof-of-principle strains by Sajo Mienda, Bashir

Get full text

Bio-succinic acid production: Escherichia coli strains design from genome-scale perspectives by Sajo Mienda, Bashir, Mohd Salleh, Faezah

“…Escherichia coli (E. coli) has been established to be a native producer of succinic acid (a platform chemical with different applications) via mixed acid…”
Get full text

Model-driven in Silico glpC Gene Knockout Predicts Increased Succinate Production from Glycerol in Escherichia Coli by Sajo Mienda, Bashir, Shahir Shamsir, Mohd

“…Metabolic engineered targeting for increased succinate production in Escherichia coli using glycerol as a low cost carbon source has attracted global attention…”
Get full text

An overview of pathway prediction tools for synthetic design of microbial chemical factories by Sajo Mienda, Bashir, Shahir Shamsir, Mohd

“…The increasing need for the bio-based industrial production of compounds via microbial cell factories leads to a demand for computational pathway prediction…”
Get full text

Genome-scale metabolic models as platforms for identification of novel genes as antimicrobial drug targets by Mienda, Bashir Sajo, Salihu, Rabiu, Adamu, Aliyu, Idris, Shehu

“…The growing number of multidrug-resistant pathogenic bacteria is becoming a world leading challenge for the scientific community and for public health…”
Get full text

Genome-scale metabolic models as platforms for strain design and biological discovery by Mienda, Bashir Sajo

“…Genome-scale metabolic models (GEMs) have been developed and used in guiding systems' metabolic engineering strategies for strain design and development. This…”
Get full text

Genome-Scale Metabolic Modeling of Escherichia coli and Its Chassis Design for Synthetic Biology Applications by Mienda, Bashir Sajo, Dräger, Andreas

“…Genome-scale metabolic modeling is and will continue to play a central role in computational systems metabolic engineering and synthetic biology applications…”
Get more information

Escherichia coli genome-scale metabolic gene knockout of lactate dehydrogenase (ldhA), increases succinate production from glycerol by Mienda, Bashir Sajo

“…Genome-scale metabolic model (GEM) of Escherichia coli has been published with applications in predicting metabolic engineering capabilities on different…”
Get full text

In silico deletion of PtsG gene in Escherichia coli genome-scale model predicts increased succinate production from glycerol by Mienda, Bashir Sajo, Shamsir, Mohd Shahir

“…Systems metabolic engineering and in silico analyses are necessary to study gene knockout candidate for enhanced succinic acid production by Escherichia coli…”
Get full text

In silico prediction of gene knockout candidates in Escherichia coli genome-scale model for enhanced succinic acid production from glycerol by Mienda, Bashir Sajo, Shamsir, Mohd Shahir, Illias, Rosli Md

“…The use of genome-scale models of Escherichia coli to guide future metabolic engineering strategies for increased succinic acid production has received renewed…”
Get full text

153 Model-aided anaerobic metabolic gene knockout of malate dehydrogenase (mdh) gene predicts increased succinate production in Escherichia coli by Mienda, Bashir Sajo, Shamsir, Mohd Shahir

Get full text

Model-aided atpE gene knockout strategy in Escherichia coli for enhanced succinic acid production from glycerol by Mienda, Bashir Sajo, Shamsir, Mohd Shahir, Md. Illias, Rosli

“…Succinic acid is an important platform chemical with a variety of applications. Model-guided metabolic engineering strategies in Escherichia coli for strain…”
Get full text

Theoretical analyses on enantiospecificity of L-2-haloacid dehalogenase (DehL) from Rhizobium sp. RC1 towards 2-chloropropionic acid by Adamu, Aliyu, Abdul Wahab, Roswanira, Aliyu, Firdausi, Abdul Razak, Fazira Ilyana, Mienda, Bashir Sajo, Shamsir, Mohd Shahir, Huyop, Fahrul

“…Dehalogenases continue to garner interest of the scientific community due to their potential applications in bioremediation of halogen-contaminated environment…”
Get full text

Model-assisted formate dehydrogenase-O (fdoH) gene knockout for enhanced succinate production in Escherichia coli from glucose and glycerol carbon sources by Mienda, Bashir Sajo, Shamsir, Mohd Shahir, Md. Illias, Rosli

“…Succinic acid is an important platform chemical that has broad applications and is been listed as one of the top twelve bio-based chemicals produced from…”
Get full text

Model-guided metabolic gene knockout of gnd for enhanced succinate production in Escherichia coli from glucose and glycerol substrates by Mienda, Bashir Sajo, Shamsir, Mohd Shahir, Illias, Rosli Md

“…[Display omitted] •Model-guided gnd gene knockout strategy was applied for the first time in Escherichia coli for increased succinate production.•The model…”
Get full text

In silico prediction of Escherichia coli metabolic engineering capabilities for 1-butanol production by Mienda, Bashir Sajo, Shamsir, Mohd Shahir, Salleh, Faezah Mohd, Illias, Rosli Md

“…In silico metabolic engineering interventions have received renewed attention due to the increase in the number of annotated genomes and the development of…”
Get full text