Search Results - "Miell, John"

IGF-Binding Protein-2 Protects Against the Development of Obesity and Insulin Resistance by WHEATCROFT, Stephen B, KEARNEY, Mark T, SETHI, Jaswinder K, CROSSEY, Paul A, SHAH, Ajay M, EZZAT, Vivienne A, MIELL, John R, MODO, Michael, WILLIAMS, Stephen C. R, CAWTHORN, Will P, MEDINA-GOMEZ, Gema, VIDAL-PUIG, Antonio

“…IGF-Binding Protein-2 Protects Against the Development of Obesity and Insulin Resistance Stephen B. Wheatcroft 1 , Mark T. Kearney 1 , Ajay M. Shah 2 ,…”
Get full text

The Relationship among Circulating Insulin-Like Growth Factor (IGF)-I, IGF-Binding Proteins-1 and -2, and Birth Anthropometry: A Prospective Study by Boyne, Michael S., Thame, Minerva, Bennett, Franklyn I., Osmond, Clive, Miell, John P., Forrester, Terrence E.

“…Fetal IGF-I is a determinant of birth weight, but whether maternal IGF-I plays a significant role is controversial. We sought to examine the relationships…”
Get full text

Acute Toxicity Related to 25G-NBOMe Use: An Internet High by Brooks, Chloe, Gibson, Alexander R, Miell, John

“…The NBOMe series is an emerging class of synthetic hallucinogens with limited data available on their use and effects. Whilst toxicity to related substances…”
Get full text

Vascular Endothelial Function and Blood Pressure Homeostasis in Mice Overexpressing IGF Binding Protein-1 by WHEATCROFT, Stephen B, KEARNEY, Mark T, SHAH, Ajay M, GRIEVE, David J, WILLIAMS, Ian L, MIELL, John P, CROSSEY, Paul A

“…Vascular Endothelial Function and Blood Pressure Homeostasis in Mice Overexpressing IGF Binding Protein-1 Stephen B. Wheatcroft 1 , Mark T. Kearney 1 , Ajay M…”
Get full text

Dysregulation of the insulin/IGF binding protein-1 axis in transgenic mice is associated with hyperinsulinemia and glucose intolerance by Crossey, P A, Jones, J S, Miell, J P

“…Dysregulation of the insulin/IGF binding protein-1 axis in transgenic mice is associated with hyperinsulinemia and glucose intolerance. P A Crossey , J S Jones…”
Get full text

Altered placental development and intrauterine growth restriction in IGF binding protein-1 transgenic mice by Crossey, Paul A., Pillai, Claire C., Miell, John P.

Get full text

Altered placental development and intrauterine growth restriction in IGF binding protein-1 transgenic mice by Crossey, Paul A, Pillai, Claire C, Miell, John P

“…IGF binding protein-1 (IGFBP-1) is a secretory product of decidualized endometrium and a major constituent of amniotic fluid. It is thought to modulate the…”
Get full text

Orthotopic liver transplantation reverses the adverse nutritional changes of end-stage liver disease in children by Holt, RI, Broide, E, Buchanan, CR, Miell, JP, Baker, AJ, Mowat, AP, Mieli-Vergani, G

“…The changes in growth and body composition after orthotopic liver transplantation (OLT) were studied in 61 children [median age at OLT 3.49 y (range: 0.04-14.5…”
Get full text

Nasogastric feeding enhances nutritional status in paediatric liver disease but does not alter circulating levels of IGF-I and IGF binding proteins by Holt, Richard, Miell, John, Jones, Jennifer, Mieli-Vergani, Giorgina, Baker, Alastair

“…OBJECTIVE Complications of childhood cirrhosis include abnormal growth and malnutrition, associated with abnormalities in circulating IGFs and IGFBPs…”
Get full text

Serum IGF-I and IGF binding proteins 2 and 3 as potential markers of doping with human GH by Kicman, Andrew T, Miell, John P, Teale, J. Derrick, Powrie, Jake, Wood, Peter J, Laidler, Paul, Milligan, Peter J, Cowan, David A

“…OBJECTIVE IGF‐I and IGF binding protein (IGFBP)‐3 levels in man are positively regulated by GH status; in contrast, evidence suggests an inverse relationship…”
Get full text

Diarrhea reduces the rates of cardiac protein synthesis in myofibrillar protein fractions in rats in vivo by Hunter, R J, Patel, V B, Miell, J P, Wong, H J, Marway, J S, Richardson, P J, Preedy, V R

“…Although chronic diarrhea affects heart function and morphology, the pathogenic mechanisms are unknown. It was our hypothesis that diarrhea imposes metabolic…”
Get more information

The Maternal Insulin-Like Growth Factor (IGF) and IGF-Binding Protein Response to Trisomic Pregnancy during the First Trimester: A Possible Diagnostic Tool for Trisomy 18 Pregnancies by Miell, John P, Langford, Katherine S, Jones, Jennifer S, Noble, Penny, Westwood, Melissa, White, Anne, Nicolaides, Kypros H

“…Many lines of evidence point to an important role for the insulin-like growth factors (IGFs) in embryonic and fetal growth in human pregnancy. The…”
Get full text

Lymph Node Involvement and Surgical Approach in Parathyroid Cancer by Schulte, Klaus-Martin, Talat, Nadia, Miell, John, Moniz, Caje, Sinha, Prakash, Diaz-Cano, Salvador

“…Background The best surgical approach to parathyroid cancer is disputed. Recommendations vary and are built on incoherent evidence. High rates of recurrence…”
Get full text

Effects of dexamethasone on growth hormone (GH)-releasing hormone, arginine- and dopaminergic stimulated GH secretion, and total plasma insulin-like growth factor-I concentrations in normal male volunteers by Miell, J P, Corder, R, Pralong, F P, Gaillard, R C

“…In man, glucocorticoid treatment and endogenous corticosteroid excess generally suppress stimulated GH release. However, such effects are not entirely…”
Get more information

Administration of human recombinant insulin-like growth factor-I to patients following major gastrointestinal surgery by Miell, J P, Taylor, A M, Jones, J, Buchanan, C R, Rennie, J, Sherwood, R, Leicester, R, Ross, R J

“…The aim was to study the pharmacokinetic parameters and biological activity of a single dose of human recombinant IGF-I (rhIGF-I) administered to patients…”
Get more information

Low-dose hydrocortisone in chronic fatigue syndrome: a randomised crossover trial by Cleare, Anthony J, Heap, Emma, Malhi, Gin S, Wessely, Simon, O'Keane, Veronica, Miell, John

“…Reports of mild hypocortisolism in chronic fatigue syndrome led us to postulate that low-dose hydrocortisone therapy may be an effective treatment. In a…”
Get full text

Application of proton NMR spectroscopy to measurement of whole-body RNA degradation rates: effects of surgical stress in human patients by Marway, Jaspaul S., Anderson, Graeme J., Miell, John P., Ross, Richard, Grimble, George K., Bonner, Adrian B., Gibbons, William A., Peters, Timothy J., Preedy, Victor R.

“…The urinary catabolites, N 2, N 2-dimethylguanosine (DMG), pseudouridine (PSU) and 7-methylguanine (m 7-Gua) are formed from post-transcriptional methylation…”
Get full text

Critically ill patients have high basal growth hormone levels with attenuated oscillatory activity associated with low levels of insulin-like growth factor-I by Ross, R, Miell, J, Freeman, E, Jones, J, Matthews, D, Preece, M, Buchanan, C

“…The aim was to study the relationship between growth hormone (GH) and insulin-like growth factor-I (IGF-I) in critically ill patients. Case-control study of…”
Get more information

Temporal changes in insulin sensitivity following the development of acute liver failure secondary to acetaminophen by Clark, Sarah J., Shojaee-Moradie, Fariba, Croos, Premila, Seed, Paul T., Umpleby, A.Margot, Wendon, Julia A., Miell, John

“…Insulin resistance in chronic liver disease (CLD) is well documented. This study investigated whether similar changes occur in acute liver failure (ALF)…”
Get full text

Effects of hypothyroidism and hyperthyroidism on insulin-like growth factors (IGFs) and growth hormone- and IGF-binding proteins by Miell, J P, Taylor, A M, Zini, M, Maheshwari, H G, Ross, R J, Valcavi, R

“…Normal thyroid status is a prerequisite for the normal growth and development of many tissues. The interrelationships between the thyroid and…”
Get more information