Search Results - "Mielke, A"

Control of Lymphocyte Fate, Infection, and Tumor Immunity by TCF-1 by Raghu, Dinesh, Xue, Hai-Hui, Mielke, Lisa A.

“…T cell factor-1 (TCF-1), encoded by Tcf7, is a transcription factor and histone deacetylase (HDAC) essential for commitment to both the T cell and the innate…”
Get full text

Social bonds facilitate cooperative resource sharing in wild chimpanzees by Samuni, L, Preis, A, Mielke, A, Deschner, T, Wittig, R M, Crockford, C

“…Why share when access to benefits is uncertain is crucial to our understanding of the evolution of humans' extensive cooperation. Here, we investigated some of…”
Get full text

T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate by Mackay, Laura K., Wynne-Jones, Erica, Freestone, David, Pellicci, Daniel G., Mielke, Lisa A., Newman, Dane M., Braun, Asolina, Masson, Frederick, Kallies, Axel, Belz, Gabrielle T., Carbone, Francis R.

“…Tissue-resident memory T (Trm) cells contribute to local immune protection in non-lymphoid tissues such as skin and mucosa, but little is known about their…”
Get full text

Intergroup Competition Enhances Chimpanzee (Pan troglodytes verus) In-group Cohesion by Samuni, L., Mielke, A., Preis, A., Crockford, C., Wittig, R. M.

“…In-group cohesion is an essential component of successful intergroup competition in both human and nonhuman animals, likely facilitating group members access…”
Get full text

Nfil3 is required for the development of all innate lymphoid cell subsets by Seillet, Cyril, Rankin, Lucille C, Groom, Joanna R, Mielke, Lisa A, Tellier, Julie, Chopin, Michael, Huntington, Nicholas D, Belz, Gabrielle T, Carotta, Sebastian

“…Innate lymphoid cell (ILC) populations protect against infection and are essential for lymphoid tissue formation and tissue remodeling after damage. Nfil3 is…”
Get full text

Urinary oxytocin levels in relation to post-conflict affiliations in wild male chimpanzees (Pan troglodytes verus) by Preis, Anna, Samuni, L., Mielke, A., Deschner, T., Crockford, C., Wittig, R.M.

“…Many animals living in social groups have evolved behaviors to resolve conflicts between group members, behaviors thought crucial for maintaining stable group…”
Get full text

Effector and stem-like memory cell fates are imprinted in distinct lymph node niches directed by CXCR3 ligands by Duckworth, Brigette C., Lafouresse, Fanny, Wimmer, Verena C., Broomfield, Benjamin J., Dalit, Lennard, Alexandre, Yannick O., Sheikh, Amania A., Qin, Raymond Z., Alvarado, Carolina, Mielke, Lisa A., Pellegrini, Marc, Mueller, Scott N., Boudier, Thomas, Rogers, Kelly L., Groom, Joanna R.

“…T cells dynamically interact with multiple, distinct cellular subsets to determine effector and memory differentiation. Here, we developed a platform to…”
Get full text

Deciphering the Innate Lymphoid Cell Transcriptional Program by Seillet, Cyril, Mielke, Lisa A., Amann-Zalcenstein, Daniela B., Su, Shian, Gao, Jerry, Almeida, Francisca F., Shi, Wei, Ritchie, Matthew E., Naik, Shalin H., Huntington, Nicholas D., Carotta, Sebastian, Belz, Gabrielle T.

“…Innate lymphoid cells (ILCs) are enriched at mucosal surfaces, where they provide immune surveillance. All ILC subsets develop from a common progenitor that…”
Get full text

Complementarity and redundancy of IL-22-producing innate lymphoid cells by Rankin, Lucille C, Girard-Madoux, Mathilde J H, Seillet, Cyril, Mielke, Lisa A, Kerdiles, Yann, Fenis, Aurore, Wieduwild, Elisabeth, Putoczki, Tracy, Mondot, Stanislas, Lantz, Olivier, Demon, Dieter, Papenfuss, Anthony T, Smyth, Gordon K, Lamkanfi, Mohamed, Carotta, Sebastian, Renauld, Jean-Christophe, Shi, Wei, Carpentier, Sabrina, Soos, Tim, Arendt, Christopher, Ugolini, Sophie, Huntington, Nicholas D, Belz, Gabrielle T, Vivier, Eric

“…The function of group 3 innate lymphoid cells (ILC3 cells) is still being determined. Vivier and colleagues describe the development of ILC3 subsets and show…”
Get full text

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease by Tye, Hazel, Yu, Chien-Hsiung, Simms, Lisa A., de Zoete, Marcel R., Kim, Man Lyang, Zakrzewski, Martha, Penington, Jocelyn S., Harapas, Cassandra R., Souza-Fonseca-Guimaraes, Fernando, Wockner, Leesa F., Preaudet, Adele, Mielke, Lisa A., Wilcox, Stephen A., Ogura, Yasunori, Corr, Sinead C., Kanojia, Komal, Kouremenos, Konstantinos A., De Souza, David P., McConville, Malcolm J., Flavell, Richard A., Gerlic, Motti, Kile, Benjamin T., Papenfuss, Anthony T., Putoczki, Tracy L., Radford-Smith, Graham L., Masters, Seth L.

“…Anti-microbial signaling pathways are normally triggered by innate immune receptors when detecting pathogenic microbes to provide protective immunity. Here we…”
Get full text

Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT by Chopin, Michaël, Lun, Aaron T., Zhan, Yifan, Schreuder, Jaring, Coughlan, Hannah, D’Amico, Angela, Mielke, Lisa A., Almeida, Francisca F., Kueh, Andrew J., Dickins, Ross A., Belz, Gabrielle T., Naik, Shalin H., Lew, Andrew M., Bouillet, Phillipe, Herold, Marco J., Smyth, Gordon K., Corcoran, Lynn M., Nutt, Stephen L.

“…Dendritic cells (DCs) are can be broadly divided into conventional (cDC) and plasmacytoid (pDC) subsets. Despite the importance of this lineage diversity, its…”
Get full text

Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells by Sathe, Priyanka, Delconte, Rebecca B., Souza-Fonseca-Guimaraes, Fernando, Seillet, Cyril, Chopin, Michael, Vandenberg, Cassandra J., Rankin, Lucille C., Mielke, Lisa A., Vikstrom, Ingela, Kolesnik, Tatiana B., Nicholson, Sandra E., Vivier, Eric, Smyth, Mark J., Nutt, Stephen L., Glaser, Stefan P., Strasser, Andreas, Belz, Gabrielle T., Carotta, Sebastian, Huntington, Nicholas D.

“…The cytokine IL-15 is required for natural killer (NK) cell homeostasis; however, the intrinsic mechanism governing this requirement remains unexplored. Here…”
Get full text

The TNF Receptor Superfamily-NF-κB Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues by Vasanthakumar, Ajithkumar, Liao, Yang, Teh, Peggy, Pascutti, Maria F., Oja, Anna E., Garnham, Alexandra L., Gloury, Renee, Tempany, Jessica C., Sidwell, Tom, Cuadrado, Eloy, Tuijnenburg, Paul, Kuijpers, Taco W., Lalaoui, Najoua, Mielke, Lisa A., Bryant, Vanessa L., Hodgkin, Philip D., Silke, John, Smyth, Gordon K., Nolte, Martijn A., Shi, Wei, Kallies, Axel

“…After exiting the thymus, Foxp3+ regulatory T (Treg) cells undergo further differentiation in the periphery, resulting in the generation of mature, fully…”
Get full text

Energetic formulation of multiplicative elasto-plasticity using dissipation distances by Mielke, A.

“…We introduce a new energetic formulation for the inelastic rate-independent behavior of standard generalized materials. This formulation is solely based on the…”
Get full text

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15 by Delconte, Rebecca B., Shi, Wei, Sathe, Priyanka, Ushiki, Takashi, Seillet, Cyril, Minnich, Martina, Kolesnik, Tatiana B., Rankin, Lucille C., Mielke, Lisa A., Zhang, Jian-Guo, Busslinger, Meinrad, Smyth, Mark J., Hutchinson, Dana S., Nutt, Stephen L., Nicholson, Sandra E., Alexander, Warren S., Corcoran, Lynn M., Vivier, Eric, Belz, Gabrielle T., Carotta, Sebastian, Huntington, Nicholas D.

“…The inhibitor of DNA binding 2 (Id2) is essential for natural killer (NK) cell development with its canonical role being to antagonize E-protein function and…”
Get full text

Assessment of the Ferroptosis Regulators: Glutathione Peroxidase 4, Acyl-Coenzyme A Synthetase Long-Chain Family Member 4, and Transferrin Receptor 1 in Patient-Derived Endometriosis Tissue by Mielke Cabello, Lidia A, Meresman, Gabriela, Darici, Dogus, Carnovale, Noelia, Heitkötter, Birthe, Schulte, Miriam, Espinoza-Sánchez, Nancy A, Le, Quang-Khoi, Kiesel, Ludwig, Schäfer, Sebastian D, Götte, Martin

“…Ferroptosis, an iron-dependent form of non-apoptotic cell death, plays a pivotal role in various diseases and is gaining considerable attention in the realm of…”
Get full text

Type 2 Innate Lymphoid Cells Protect against Colorectal Cancer Progression and Predict Improved Patient Survival by Huang, Qiutong, Jacquelot, Nicolas, Preaudet, Adele, Hediyeh-Zadeh, Soroor, Souza-Fonseca-Guimaraes, Fernando, McKenzie, Andrew N J, Hansbro, Philip M, Davis, Melissa J, Mielke, Lisa A, Putoczki, Tracy L, Belz, Gabrielle T

“…Chronic inflammation of the gastrointestinal (GI) tract contributes to colorectal cancer (CRC) progression. While the role of adaptive T cells in CRC is now…”
Get full text

Properties of Hubbard models with degenerate localised single-particle eigenstates by Mielke, A.

“…We consider the repulsive Hubbard model on a class of lattices or graphs for which there is a large degeneracy of the single-particle ground states and where…”
Get full text

Complexity of cytokine network regulation of innate lymphoid cells in protective immunity by Seillet, Cyril, Belz, Gabrielle T., Mielke, Lisa A.

“…The body’s surface provides a critical barrier shielding us from various mechanical and pathogenic insults by virtue of the physical protection it provides and…”
Get full text

High Expression of CAI2, a 9p21-Embedded Long Noncoding RNA, Contributes to Advanced-Stage Neuroblastoma by BARNHILL, Lisa M, WILLIAMS, Richard T, DICCIANNI, Mitchell B, COHEN, Olga, YOUNGJIN KIM, BATOVA, Ayse, MIELKE, Jenna A, MESSER, Karen, MINYA PU, LEI BAO, YU, Alice L

“…Neuroblastoma is a pediatric cancer with significant genomic and biologic heterogeneity. p16 and ARF, two important tumor-suppressor genes on chromosome 9p21,…”
Get full text