Search Results - "Middleditch, J."

REVIEW: The detection of aquatic animal species using environmental DNA – a review of eDNA as a survey tool in ecology by Rees, Helen C, Maddison, Ben C, Middleditch, David J, Patmore, James R.M, Gough, Kevin C, Crispo, Erika

“…Knowledge of species distribution is critical to ecological management and conservation biology. Effective management requires the detection of populations,…”
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TAS‐120 Cancer Target Binding: Defining Reactivity and Revealing the First Fibroblast Growth Factor Receptor 1 (FGFR1) Irreversible Structure by Kalyukina, Maria, Yosaatmadja, Yuliana, Middleditch, Martin J., Patterson, Adam V., Smaill, Jeff B., Squire, Christopher J.

“…1‐[(3S)‐3‐[4‐Amino‐3‐[2‐(3,5‐dimethoxyphenyl)ethynyl]‐1H‐pyrazolo[3,4‐d]pyrimidin‐1‐yl]‐1‐pyrrolidinyl]‐2‐propen‐1‐one (TAS‐120) is an irreversible inhibitor…”
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Predicting the Starquakes in PSR J0537–6910 by Middleditch, J, Marshall, F. E, Wang, Q. D, Gotthelf, E. V, Zhang, W

“…We report on more than 7 yr of monitoring of PSR J0537-6910, the 16 ms pulsar in the LMC, using data acquired with RXTE. During this campaign the pulsar…”
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Poly-γ-glutamylation of biomolecules by Bashiri, Ghader, Bulloch, Esther M. M., Bramley, William R., Davidson, Madison, Stuteley, Stephanie M., Young, Paul G., Harris, Paul W. R., Naqvi, Muhammad S. H., Middleditch, Martin J., Schmitz, Michael, Chang, Wei-Chen, Baker, Edward N., Squire, Christopher J.

“…Poly-γ-glutamate tails are a distinctive feature of archaeal, bacterial, and eukaryotic cofactors, including the folates and F 420 . Despite decades of…”
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The application of eDNA for monitoring of the Great Crested Newt in the UK by Rees, Helen C., Bishop, Keith, Middleditch, David J., Patmore, James R. M., Maddison, Ben C., Gough, Kevin C.

“…Current ecological surveys for great crested newts are time‐consuming and expensive and can only be carried out within a short survey window. Additional survey…”
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Mapping Autoantibodies in Children With Acute Rheumatic Fever by McGregor, Reuben, Tay, Mei Lin, Carlton, Lauren H, Hanson-Manful, Paulina, Raynes, Jeremy M, Forsyth, Wasan O, Brewster, Diane T, Middleditch, Martin J, Bennett, Julie, Martin, William John, Wilson, Nigel, Atatoa Carr, Polly, Baker, Michael G, Moreland, Nicole J

“…Acute rheumatic fever (ARF) is a serious sequela of Group A (GAS) infection associated with significant global mortality. Pathogenesis remains poorly…”
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Applications and limitations of measuring environmental DNA as indicators of the presence of aquatic animals by Rees, Helen C., Gough, Kevin C., Middleditch, David J., Patmore, James R. M., Maddison, Ben C.

“…1. In Rees et al. (2014b), we reviewed the current status of environmental DNA (eDNA) to monitor aquatic populations. Our aim was to focus on discussion of…”
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Crystal Structure of the Minor Pilin FctB Reveals Determinants of Group A Streptococcal Pilus Anchoring by Linke, Christian, Young, Paul G., Kang, Hae Joo, Bunker, Richard D., Middleditch, Martin J., Caradoc-Davies, Tom T., Proft, Thomas, Baker, Edward N.

“…Cell surface pili are polymeric protein assemblies that enable bacteria to adhere to surfaces and to specific host tissues. The pili expressed by Gram-positive…”
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A White Dwarf Merger Paradigm for Supernovae and Gamma-Ray Bursts by Middleditch, J

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Utility of the Leptospermum scoparium Compound Lepteridine as a Chemical Marker for Manuka Honey Authenticity by Lin, Bin, Daniels, Benjamin J, Middleditch, Martin J, Furkert, Daniel P, Brimble, Margaret A, Bong, Jessie, Stephens, Jonathan M, Loomes, Kerry M

“…Manuka honey is a premium food product with unique antimicrobial bioactivity. Concerns with mislabeled manuka honey require robust assays to determine…”
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Crystal structure of kiwellin, a major cell-wall protein from kiwifruit by Hamiaux, Cyril, Maddumage, Ratnasiri, Middleditch, Martin J., Prakash, Roneel, Brummell, David A., Baker, Edward N., Atkinson, Ross G.

“…Kiwellin is a cysteine-rich, cell wall-associated protein with no known structural homologues. It is one of the most abundant proteins in kiwifruit (Actinidia…”
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The detection of aquatic animal species using environmental DNA – a review of eDNA as a survey tool in ecology by Rees, Helen C., Maddison, Ben C., Middleditch, David J., Patmore, James R.M., Gough, Kevin C.

“…1. Knowledge of species distribution is critical to ecological management and conservation biology. Effective management requires the detection of populations,…”
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Is the failing heart out of fuel or a worn engine running rich? A study of mitochondria in old spontaneously hypertensive rats by Jüllig, Mia, Hickey, Anthony J.R, Chai, Chau C, Skea, Gretchen L, Middleditch, Martin J, Costa, Silvana, Choong, Soon Y, Philips, Anthony R.J, Cooper, Garth J.S

“…Hypertension now affects about 600 million people worldwide and is a leading cause of death in the Western world. The spontaneously hypertensive rat (SHR),…”
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The Big Glitcher: The Rotation History of PSR J0537–6910 by Marshall, F. E, Gotthelf, E. V, Middleditch, J, Wang, Q. D, Zhang, W

“…We report the results of an extensive monitoring campaign of PSR J0537-6910, the 16 ms pulsar in the Large Magellanic Cloud, using data acquired with the Rossi…”
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Discovery of an Ultrafast X-Ray Pulsar in the Supernova Remnant N157B by Marshall, F. E, Gotthelf, E. V, Zhang, W, Middleditch, J, Wang, Q. D

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Identification of key residues involved in adrenomedullin binding to the AM1 receptor by Watkins, HA, Au, M, Bobby, R, Archbold, JK, Abdul‐Manan, N, Moore, JM, Middleditch, MJ, Williams, GM, Brimble, MA, Dingley, AJ, Hay, DL

“…Background and Purpose Adrenomedullin (AM) is a peptide hormone whose receptors are members of the class B GPCR family. They comprise a heteromer between the…”
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A conserved glutamate residue in RPM1-INTERACTING PROTEIN4 is ADP-ribosylated by the Pseudomonas effector AvrRpm2 to activate RPM1-mediated plant resistance by Yoon, Minsoo, Middleditch, Martin J, Rikkerink, Erik H A

“…Gram-negative bacterial plant pathogens inject effectors into their hosts to hijack and manipulate metabolism, eluding surveillance at the battle frontier on…”
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Cephazolin and gentamicin are stable in lactate-buffered fresenius peritoneal dialysate for seven days at room temperature by Singh, Gillian K Balbir, Wolley, Martin J, Laycock, Valmai C, Voss, David M, Middleditch, Martin J, Marshall, Mark R

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Itaconate is a covalent inhibitor of the Mycobacterium tuberculosis isocitrate lyase by Kwai, Brooke X. C., Collins, Annabelle J., Middleditch, Martin J., Sperry, Jonathan, Bashiri, Ghader, Leung, Ivanhoe K. H.

“…Itaconate is a mammalian antimicrobial metabolite that inhibits the isocitrate lyases (ICLs) of Mycobacterium tuberculosis . Herein, we report that ICLs form a…”
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Domain structure and cross-linking in a giant adhesin from the Mobiluncus mulieris bacterium by Young, Paul G., Paynter, Jacob M., Wardega, Julia K., Middleditch, Martin J., Payne, Leo S., Baker, Edward N., Squire, Christopher J.

“…Cell-surface proteins known as adhesins enable bacteria to colonize particular environments, and in Gram-positive bacteria often contain autocatalytically…”
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