Search Results - "Middelkoop, Teije C"

Feedback Control of Gene Expression Variability in the Caenorhabditis elegans Wnt Pathway by Ji, Ni, Middelkoop, Teije C., Mentink, Remco A., Betist, Marco C., Tonegawa, Satto, Mooijman, Dylan, Korswagen, Hendrik C., van Oudenaarden, Alexander

“…Variability in gene expression contributes to phenotypic heterogeneity even in isogenic populations. Here, we used the stereotyped, Wnt signaling-dependent…”
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Cell lineage-dependent chiral actomyosin flows drive cellular rearrangements in early Caenorhabditis elegans development by Pimpale, Lokesh G, Middelkoop, Teije C, Mietke, Alexander, Grill, Stephan W

“…Proper positioning of cells is essential for many aspects of development. Daughter cell positions can be specified via orienting the cell division axis during…”
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Cell Intrinsic Modulation of Wnt Signaling Controls Neuroblast Migration in C. elegans by Mentink, Remco A., Middelkoop, Teije C., Rella, Lorenzo, Ji, Ni, Tang, Chung Yin, Betist, Marco C., van Oudenaarden, Alexander, Korswagen, Hendrik C.

“…Members of the Wnt family of secreted signaling proteins are key regulators of cell migration and axon guidance. In the nematode C. elegans, the migration of…”
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Governing principles of transcriptional logic out of equilibrium by Dixit, Smruti, Middelkoop, Teije C, Choubey, Sandeep

“…To survive, adapt, and develop, cells respond to external and internal stimuli by tightly regulating transcription. Transcriptional regulation involves the…”
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Molecular structure and dimeric organization of the Notch extracellular domain as revealed by electron microscopy by Kelly, Deborah F, Lake, Robert J, Middelkoop, Teije C, Fan, Hua-Ying, Artavanis-Tsakonas, Spyros, Walz, Thomas

“…The Notch receptor links cell fate decisions of one cell to that of the immediate cellular neighbor. In humans, malfunction of Notch signaling results in…”
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The thrombospondin repeat containing protein MIG-21 controls a left–right asymmetric Wnt signaling response in migrating C. elegans neuroblasts by Middelkoop, Teije C., Williams, Lisa, Yang, Pei-Tzu, Luchtenberg, Jeroen, Betist, Marco C., Ji, Ni, van Oudenaarden, Alexander, Kenyon, Cynthia, Korswagen, Hendrik C.

“…Wnt proteins are secreted signaling molecules that play a central role in development and adult tissue homeostasis. Although several Wnt signal transduction…”
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Caenorhabditis elegans cyclin D/CDK4 and cyclin E/CDK2 induce distinct cell cycle re-entry programs in differentiated muscle cells by Korzelius, Jerome, The, Inge, Ruijtenberg, Suzan, Prinsen, Martine B W, Portegijs, Vincent, Middelkoop, Teije C, Groot Koerkamp, Marian J, Holstege, Frank C P, Boxem, Mike, van den Heuvel, Sander

“…Cell proliferation and differentiation are regulated in a highly coordinated and inverse manner during development and tissue homeostasis. Terminal…”
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Actomyosin-driven left-right asymmetry: from molecular torques to chiral self organization by Naganathan, Sundar Ram, Middelkoop, Teije C, Fürthauer, Sebastian, Grill, Stephan W

“…Chirality or mirror asymmetry is a common theme in biology found in organismal body plans, tissue patterns and even in individual cells. In many cases the…”
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A cytokinetic ring-driven cell rotation achieves Hertwig's rule in early development by Middelkoop, Teije C, Neipel, Jonas, Cornell, Caitlin E, Naumann, Ronald, Pimpale, Lokesh G, Jülicher, Frank, Grill, Stephan W

“…Hertwig's rule states that cells divide along their longest axis, usually driven by forces acting on the mitotic spindle. Here, we show that in contrast to…”
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Partially overlapping guidance pathways focus the activity of UNC-40/DCC along the anteroposterior axis of polarizing neuroblasts by Ebbing, Annabel, Middelkoop, Teije C, Betist, Marco, Bodewes, Eduard, Korswagen, Hendrik C

“…Directional migration of neurons and neuronal precursor cells is a central process in nervous system development. In the nematode , the two Q neuroblasts…”
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CYK-1/Formin activation in cortical RhoA signaling centers promotes organismal left–right symmetry breaking by Middelkoop, Teije C., Garcia-Baucells, Júlia, Quintero-Cadena, Porfirio, Pimpale, Lokesh G., Yazdi, Shahrzad, Sternberg, Paul W., Gross, Peter, Grill, Stephan W.

“…Proper left–right symmetry breaking is essential for animal development, and in many cases, this process is actomyosin-dependent. In Caenorhabditis elegans…”
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A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion by Silhankova, Marie, Cullen, Peter J, Korswagen, Hendrik C, Harterink, Martin, Port, Fillip, Lorenowicz, Magdalena J, McGough, Ian J, Betist, Marco C, van Weering, Jan R. T, van Heesbeen, Roy G. H. P, Middelkoop, Teije C, Basler, Konrad

“…Wnt proteins are lipid-modified glycoproteins that play a central role in development, adult tissue homeostasis and disease. Secretion of Wnt proteins is…”
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Neuroblast migration along the anteroposterior axis of C. elegans is controlled by opposing gradients of Wnts and a secreted Frizzled-related protein by Harterink, Martin, Kim, Dong Hyun, Middelkoop, Teije C, Doan, Thang Dinh, van Oudenaarden, Alexander, Korswagen, Hendrik C

“…The migration of neuroblasts along the anteroposterior body axis of C. elegans is controlled by multiple Wnts that act partially redundantly to guide cells to…”
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Inhibition of late endosomal maturation restores Wnt secretion in Caenorhabditis elegans vps-29 retromer mutants by Lorenowicz, Magdalena J., Macurkova, Marie, Harterink, Martin, Middelkoop, Teije C., de Groot, Reinoud, Betist, Marco C., Korswagen, Hendrik C.

“…Secretion of Wnt proteins is mediated by the Wnt sorting receptor Wls, which transports Wnt from the Golgi to the cell surface for release. To maintain…”
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UNC-4 antagonizes Wnt signaling to regulate synaptic choice in the C. elegans motor circuit by Schneider, Judsen, Skelton, Rachel L, Von Stetina, Stephen E, Middelkoop, Teije C, van Oudenaarden, Alexander, Korswagen, Hendrik C, Miller, 3rd, David M

“…Coordinated movement depends on the creation of synapses between specific neurons in the motor circuit. In C. elegans, this important decision is regulated by…”
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Development and migration of the C. elegans Q neuroblasts and their descendants by Middelkoop, Teije C, Korswagen, Hendrik C

“…During the first stage of larval development, the Q neuroblasts and their descendants migrate to well-defined positions along the anteroposterior body axis,…”
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Caenorhabditis elegans Cyclin D/CDK4 and Cyclin E/CDK2 Induce Distinct Cell Cycle Re-Entry Programs in Differentiated Muscle Cells: e1002362 by Korzelius, Jerome, The, Inge, Ruijtenberg, Suzan, Prinsen, Martine BW, Portegijs, Vincent, Middelkoop, Teije C, Koerkamp, Marian JGroot, Holstege, Frank CP, Boxem, Mike, Heuvel, Sander vanden

“…Cell proliferation and differentiation are regulated in a highly coordinated and inverse manner during development and tissue homeostasis. Terminal…”
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