Search Results - "Middel, Volker"

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  1. 1

    Mandipropamid as a chemical inducer of proximity for in vivo applications by Ziegler, Michael J., Yserentant, Klaus, Dunsing, Valentin, Middel, Volker, Gralak, Antoni J., Pakari, Kaisa, Bargstedt, Jörn, Kern, Christoph, Petrich, Annett, Chiantia, Salvatore, Strähle, Uwe, Herten, Dirk-Peter, Wombacher, Richard

    Published in Nature chemical biology (01-01-2022)
    “…Direct control of protein interactions by chemically induced protein proximity holds great potential for both cell and synthetic biology as well as therapeutic…”
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  2. 2

    Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair by Middel, Volker, Zhou, Lu, Takamiya, Masanari, Beil, Tanja, Shahid, Maryam, Roostalu, Urmas, Grabher, Clemens, Rastegar, Sepand, Reischl, Markus, Nienhaus, Gerd Ulrich, Strähle, Uwe

    Published in Nature communications (19-09-2016)
    “…Failure to repair the sarcolemma leads to muscle cell death, depletion of stem cells and myopathy. Hence, membrane lesions are instantly sealed by a repair…”
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  3. 3

    Light-controllable dithienylethene-modified cyclic peptides: photoswitching the in vivo toxicity in zebrafish embryos by Afonin, Sergii, Babii, Oleg, Reuter, Aline, Middel, Volker, Takamiya, Masanari, Strähle, Uwe, Komarov, Igor V, Ulrich, Anne S

    Published in Beilstein journal of organic chemistry (07-01-2020)
    “…This study evaluates the embryotoxicity of dithienylethene-modified peptides upon photoswitching, using 19 analogues based on the β-hairpin scaffold of the…”
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  4. 4

    Distinct amino acid motifs carrying multiple positive charges regulate membrane targeting of dysferlin and MG53 by Zhou, Lu, Middel, Volker, Reischl, Markus, Strähle, Uwe, Nienhaus, G Ulrich

    Published in PloS one (09-08-2018)
    “…Dysferlin (Dysf) and mitsugumin53 (MG53) are two key proteins involved in membrane repair of muscle cells which are efficiently recruited to the sarcolemma…”
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  5. 5

    Caveolae disassemble upon membrane lesioning and foster cell survival by Štefl, Martin, Takamiya, Masanari, Middel, Volker, Tekpınar, Miyase, Nienhaus, Karin, Beil, Tanja, Rastegar, Sepand, Strähle, Uwe, Nienhaus, Gerd Ulrich

    Published in iScience (16-02-2024)
    “…Repair of lesions in the plasma membrane is key to sustaining cellular homeostasis. Cells maintain cytoplasmic as well as membrane-bound stores of repair…”
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  6. 6

    Inhibition of Pseudomonas aeruginosa biofilm formation and expression of virulence genes by selective epimerization in the peptide Esculentin‐1a(1‐21)NH2 by Casciaro, Bruno, Lin, Qiao, Afonin, Sergii, Loffredo, Maria Rosa, Turris, Valeria, Middel, Volker, Ulrich, Anne S., Di, YuanPu Peter, Mangoni, Maria Luisa

    Published in The FEBS journal (01-10-2019)
    “…Pseudomonas aeruginosa is a pathogenic bacterium known to cause serious human infections, especially in immune‐compromised patients. This is due to its unique…”
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    Supreme activity of gramicidin S against resistant, persistent and biofilm cells of staphylococci and enterococci by Berditsch, Marina, Afonin, Sergii, Reuster, Jennifer, Lux, Hannah, Schkolin, Kristina, Babii, Oleg, Radchenko, Dmytro S., Abdullah, Issah, William, Nicola, Middel, Volker, Strähle, Uwe, Nelson, Andrew, Valko, Klara, Ulrich, Anne S.

    Published in Scientific reports (29-11-2019)
    “…Three promising antibacterial peptides were studied with regard to their ability to inhibit the growth and kill the cells of clinical strains of Staphylococcus…”
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  11. 11

    Inhibition of Pseudomonas aeruginosa biofilm formation and expression of virulence genes by selective epimerization in the peptide Esculentin-1a(1-21)NH 2 by Casciaro, Bruno, Lin, Qiao, Afonin, Sergii, Loffredo, Maria Rosa, de Turris, Valeria, Middel, Volker, Ulrich, Anne S, Di, YuanPu Peter, Mangoni, Maria Luisa

    Published in The FEBS journal (01-10-2019)
    “…Pseudomonas aeruginosa is a pathogenic bacterium known to cause serious human infections, especially in immune-compromised patients. This is due to its unique…”
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    Journal Article
  12. 12

    Zebrafish biosensor for toxicant induced muscle hyperactivity by Shahid, Maryam, Takamiya, Masanari, Stegmaier, Johannes, Middel, Volker, Gradl, Marion, Klüver, Nils, Mikut, Ralf, Dickmeis, Thomas, Scholz, Stefan, Rastegar, Sepand, Yang, Lixin, Strähle, Uwe

    Published in Scientific reports (31-03-2016)
    “…Robust and sensitive detection systems are a crucial asset for risk management of chemicals, which are produced in increasing number and diversity. To…”
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  13. 13

    Microtome-integrated microscope system for high sensitivity tracking of in-resin fluorescence in blocks and ultrathin sections for correlative microscopy by Lemercier, Nicolas, Middel, Volker, Hentsch, Didier, Taubert, Serge, Takamiya, Masanari, Beil, Tanja, Vonesch, Jean-Luc, Baumbach, Tilo, Schultz, Patrick, Antony, Claude, Strähle, Uwe

    Published in Scientific reports (19-10-2017)
    “…Many areas of biological research demand the combined use of different imaging modalities to cover a wide range of magnifications and measurements or to place…”
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