Search Results - "Middei, S."
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AD-Related N-Terminal Truncated Tau Is Sufficient to Recapitulate In Vivo the Early Perturbations of Human Neuropathology: Implications for Immunotherapy
Published in Molecular neurobiology (01-10-2018)“…The NH 2 tau 26–44 aa (i.e., NH 2 htau) is the minimal biologically active moiety of longer 20–22-kDa NH 2 -truncated form of human tau—a neurotoxic fragment…”
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Free D-aspartate regulates neuronal dendritic morphology, synaptic plasticity, gray matter volume and brain activity in mammals
Published in Translational psychiatry (29-07-2014)“…D-aspartate (D-Asp) is an atypical amino acid, which is especially abundant in the developing mammalian brain, and can bind to and activate…”
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Progressive cognitive decline in a transgenic mouse model of Alzheimer's disease overexpressing mutant hAPPswe
Published in Genes, brain and behavior (01-04-2006)“…The possibility of detecting progressive changes in cognitive function reflecting the spatio‐temporal pattern of β‐amyloid peptide (Aβ) deposition was…”
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Region-specific changes in the microanatomy of single dendritic spines over time might account for selective memory alterations in ageing hAPPsweTg2576 mice, a mouse model for Alzheimer disease
Published in Neurobiology of learning and memory (01-09-2008)“…Tg2576 mice over-expressing human mutant APP ( hAPPswe) show progressive impairments in hippocampal plasticity and episodic memory while fronto-striatal…”
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Landmark-based but not vestibular-based orientation elicits mossy fiber synaptogenesis in the mouse hippocampus
Published in Neurobiology of learning and memory (01-02-2007)“…This study tries to shed light on the paradoxical finding that two inbred strains of mice C57BL/6 (C57) and DBA/2 (DBA), with differences in hippocampal…”
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Aspects of spatial memory and behavioral disinhibition in Tg2576 transgenic mice as a model of Alzheimer’s disease
Published in Behavioural brain research (30-01-2005)“…Transgenic mouse models of Alzheimer’s disease (AD) have been recently advanced. Tg2576 mice have been shown to develop progressive β-amyloid (Aβ) neuritic…”
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Preserved Fronto-Striatal Plasticity and Enhanced Procedural Learning in a Transgenic Mouse Model of Alzheimer's Disease Overexpressing Mutant "hAPPswe"
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-07-2004)“…Mutations in the amyloid precursor protein (APP) gene inducing abnormal processing and deposition of [beta]-amyloid protein in the brain have been implicated…”
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Genetic approach to variability of memory systems: Analysis of place vs. response learning and Fos-related expression in hippocampal and striatal areas of C57BL/6 and DBA/2 mice
Published in Hippocampus (2002)“…C57 and DBA mice were trained in a crossed maze to assess possible strain differences in place or response learning as a function of training duration ( 8 or…”
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Reversible inactivation of hippocampus and dorsolateral striatum in C57BL/6 and DBA/2 inbred mice failed to show interaction between memory systems in these genotypes
Published in Behavioural brain research (05-10-2004)“…C57BL/6 and DBA/2 mice with cannulae inserted bilaterally in the dorsal hippocampus or the dorsolateral striatum were released from the south arm of a cross…”
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Enhanced procedural learning following beta-amyloid protein (1-42) infusion in the rat
Published in Neuroreport (16-09-2002)“…Wistar rats receiving intracerebroventricular infusion of the β-amyloid protein (Aβ1-42) or of the inactive fragment (Aβ1-42) were subjected to the cross-maze…”
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P17 SPATIAL MEMORY DEFICIT AND MOTOR ACTIVITY INCREASE IN TG2576 TRANSGENIC MICE AS A MODEL OF ALZHEIMER??S DISEASE
Published in Behavioural pharmacology (01-09-2004)Get full text
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The strain-specific involvement of nucleus accumbens in latent inhibition might depend on differences in processing configural- and cue-based information between C57BL/6 and DBA mice
Published in Brain research bulletin (2002)“…Latent inhibition (LI) consists of decreased associative strength between an elemental stimulus (CS: tone) paired with an unconditioned stimulus (US:…”
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Effects of MK-801 and Ethanol Combinations on Memory Consolidation in CD1 Mice: Involvement of GABAergic Mechanisms
Published in Neurobiology of learning and memory (01-05-2002)“…In the present research the effect of the noncompetitive N-methyl-d-aspartate receptor antagonist MK-801 and ethanol combinations on memory consolidation and…”
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Potentiation of ischemia-related behavioral alterations by electro-acupuncture in gerbils
Published in Functional neurology (01-01-2004)“…Gerbils subjected to global ischemia or sham-ischemia received electro-acupuncture (EA) or sham EA at points 26 Du (Renzhong) and 8 Du (Junsuo). All animals…”
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