Search Results - "Miclea, Razvan D"

Role of Glycosylation in Conformational Stability, Activity, Macromolecular Interaction and Immunogenicity of Recombinant Human Factor VIII by Kosloski, Matthew P., Miclea, Razvan D., Balu-Iyer, Sathy V.

“…Factor VIII (FVIII) is a multi-domain glycoprotein that is an essential cofactor in the blood coagulation cascade. Its deficiency or dysfunction causes…”
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Phosphatidylserine containing liposomes reduce immunogenicity of recombinant human factor VIII (rFVIII) in a murine model of hemophilia A by Ramani, Karthik, Miclea, Razvan D, Purohit, Vivek S, Mager, Donald E, Straubinger, Robert M, Balu-Iyer, Sathy V

“…Factor VIII (FVIII) is a multidomain protein that is deficient in hemophilia A, a clinically important bleeding disorder. Replacement therapy using recombinant…”
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Effect of route of administration of human recombinant factor VIII on its immunogenicity in Hemophilia A mice by Peng, Aaron, Gaitonde, Puneet, Kosloski, Matthew P, Miclea, Razvan D, Varma, Prashant, Balu-Iyer, Sathy V

“…Factor VIII is a multi-domain glycoprotein and is an essential cofactor in the blood coagulation cascade. Its deficiency or dysfunction causes Hemophilia A, a…”
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Development and characterization of lipidic cochleate containing recombinant factor VIII by Miclea, Razvan D., Varma, Prashant R., Peng, Aaron, Balu-Iyer, Sathy V.

“…Hemophilia A, a life-threatening bleeding disorder, is caused by deficiency of factor VIII (FVIII). Replacement therapy using rFVIII is the first line therapy…”
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O-phospho-L-serine, multi-functional excipient for B domain deleted recombinant factor VIII by Miclea, Razvan D, Purohit, Vivek S, Balu-Iyer, Sathy V

“…Factor VIII (FVIII) is an important cofactor in the blood coagulation cascade. A deficiency or dysfunction of FVIII causes hemophilia A, a life-threatening…”
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Immunogenicity and pharmacokinetic studies of recombinant factor VIII containing lipid cochleates by Kosloski, Matthew P, Peng, Aaron, Varma, Prashant R, Fathallah, Anas M, Miclea, Razvan D, Mager, Donald E, Balu-iyer, Sathy V

“…Replacement therapy using recombinant factor VIII (rFVIII) is currently the most common therapy for hemophilia A, a bleeding disorder caused by the deficiency…”
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Lipid binding region (2303-2332) is involved in aggregation of recombinant human FVIII (rFVIII) by Ramani, Karthik, Purohit, Vivek S, Miclea, Razvan D, Middaugh, C Russell, Balasubramanian, Sathyamangalam V

“…Factor VIII (FVIII) is a multi-domain protein that is important in the clotting cascade. Its deficiency causes Hemophilia A, a bleeding disorder. The unfolding…”
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Phosphatidylserine mediated enhancement of the therapeutic efficacy of B domain deleted recombinant factor VIII by Miclea, Razvan D

“…Factor VIII (FVIII) is an important cofactor in the blood coagulation cascade. Deficiency or dysfunction of FVIII causes hemophilia A, a life threatening…”
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