Search Results - "Miclea, D."

Role of Glycosylation in Conformational Stability, Activity, Macromolecular Interaction and Immunogenicity of Recombinant Human Factor VIII by Kosloski, Matthew P., Miclea, Razvan D., Balu-Iyer, Sathy V.

“…Factor VIII (FVIII) is a multi-domain glycoprotein that is an essential cofactor in the blood coagulation cascade. Its deficiency or dysfunction causes…”
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Lipid binding region (2303-2332) is involved in aggregation of recombinant human FVIII (rFVIII) by Ramani, Karthik, Purohit, Vivek S, Miclea, Razvan D, Middaugh, C Russell, Balasubramanian, Sathyamangalam V

“…Factor VIII (FVIII) is a multi-domain protein that is important in the clotting cascade. Its deficiency causes Hemophilia A, a bleeding disorder. The unfolding…”
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Phosphatidylserine containing liposomes reduce immunogenicity of recombinant human factor VIII (rFVIII) in a murine model of hemophilia A by Ramani, Karthik, Miclea, Razvan D, Purohit, Vivek S, Mager, Donald E, Straubinger, Robert M, Balu-Iyer, Sathy V

“…Factor VIII (FVIII) is a multidomain protein that is deficient in hemophilia A, a clinically important bleeding disorder. Replacement therapy using recombinant…”
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Effect of route of administration of human recombinant factor VIII on its immunogenicity in Hemophilia A mice by Peng, Aaron, Gaitonde, Puneet, Kosloski, Matthew P, Miclea, Razvan D, Varma, Prashant, Balu-Iyer, Sathy V

“…Factor VIII is a multi-domain glycoprotein and is an essential cofactor in the blood coagulation cascade. Its deficiency or dysfunction causes Hemophilia A, a…”
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Development and characterization of lipidic cochleate containing recombinant factor VIII by Miclea, Razvan D., Varma, Prashant R., Peng, Aaron, Balu-Iyer, Sathy V.

“…Hemophilia A, a life-threatening bleeding disorder, is caused by deficiency of factor VIII (FVIII). Replacement therapy using rFVIII is the first line therapy…”
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Diagnosis and Management of Genetic Causes of Middle Aortic Syndrome in Children: A Comprehensive Literature Review by Lazea, Cecilia, Al-Khzouz, Camelia, Sufana, Crina, Miclea, Diana, Asavoaie, Carmen, Filimon, Ioana, Fufezan, Otilia

“…Middle aortic syndrome (MAS) is a rare vascular disease representing an important cause of severe hypertension in children. MAS is characterized by segmental…”
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O-phospho-L-serine, multi-functional excipient for B domain deleted recombinant factor VIII by Miclea, Razvan D, Purohit, Vivek S, Balu-Iyer, Sathy V

“…Factor VIII (FVIII) is an important cofactor in the blood coagulation cascade. A deficiency or dysfunction of FVIII causes hemophilia A, a life-threatening…”
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Immunogenicity and pharmacokinetic studies of recombinant factor VIII containing lipid cochleates by Kosloski, Matthew P, Peng, Aaron, Varma, Prashant R, Fathallah, Anas M, Miclea, Razvan D, Mager, Donald E, Balu-iyer, Sathy V

“…Replacement therapy using recombinant factor VIII (rFVIII) is currently the most common therapy for hemophilia A, a bleeding disorder caused by the deficiency…”
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Comparison of the haemodynamic actions of desflurane/N2O and isoflurane/N2O anaesthesia in vascular surgical patients by Zubicki, A., Gostin, X., Miclea, D., Rrou, B., Buy, E., Richer, C., Coriat, P.

“…Background: The purpose of this study was to compare heart rate and arterial blood pressure response to desflurane/N2O vs isoflurane/N2O anaesthesia in a…”
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Clinical and genetic characteristics in a group of 45 patients with Turner syndrome (monocentric study) by Bucerzan, Simona, Miclea, Diana, Popp, Radu, Alkhzouz, Camelia, Lazea, Cecilia, Pop, Ioan Victor, Grigorescu-Sido, Paula

“…Recent years have seen a shift in perspective on Turner syndrome, as it is no longer considered a significant disability due to therapeutic advances. The delay…”
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Skeletal Abnormalities and VDR1 Gene Polymorphisms in Mucopolysaccharidosis Patients by Alkhzouz, Camelia, Cabau, Georgiana, Lazea, Cecilia, Asavoaie, Carmen, Bucerzan, Simona, Mirea, Andreea Manuela, Farcas, Marius, Miclaus Jnr, Maria, Popp, Radu, Miclea, Diana

“…Articular and bone damage, which is so disabling in Mucopolysaccharidosis (MPS), requires attention as to the explanatory bias of the pathogenetic mechanisms…”
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Diagnostic Usefulness of MLPA Techniques for Recurrent Copy Number Variants Detection in Global Developmental Delay/Intellectual Disability by Miclea, Diana, Szucs, Adriana, Mirea, Andreea, Stefan, Delia-Maria, Nazarie, Florina, Bucerzan, Simona, Lazea, Cecilia, Grama, Alina, Pop, Tudor Lucian, Farcas, Marius, Zaharie, Gabriela, Matyas, Melinda, Mager, Monica, Vintan, Mihaela, Popp, Radu, Alkhzouz, Camelia

“…Genetic testing has become a standardized practice in the diagnosis of patients with global developmental delay/intellectual disability (GDD/ID). The aim of…”
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Is it important to assess patients satisfaction in ICU?: A-654 by Ionescu, D., Vele, L., Miclea, D., Ariesan, D.

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Is it important to assess patients satisfaction in ICU?: A-654 by Ionescu, D, Vele, L, Miclea, D, Ariesan, D

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Comparison of the haemodynamic actions of desflurane/N 2 O and isoflurane/N 2 O anaesthesia in vascular surgical patients by Zubicki, A., Gostin, X., Miclea, D., Rrou, B., Buy, E., Richer, C., Coriat, P.

“…Background: The purpose of this study was to compare heart rate and arterial blood pressure response to desflurane/N 2 O vs isoflurane/N 2 O anaesthesia in a…”
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Phosphatidylserine mediated enhancement of the therapeutic efficacy of B domain deleted recombinant factor VIII by Miclea, Razvan D

“…Factor VIII (FVIII) is an important cofactor in the blood coagulation cascade. Deficiency or dysfunction of FVIII causes hemophilia A, a life threatening…”
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