Search Results - "Micksche, M"

Vaults and the major vault protein: Novel roles in signal pathway regulation and immunity by Berger, W, Steiner, E, Grusch, M, Elbling, L, Micksche, M

“…The unique and evolutionary highly conserved major vault protein (MVP) is the main component of ubiquitous, large cellular ribonucleoparticles termed vaults…”
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FGF5 as an oncogenic factor in human glioblastoma multiforme: autocrine and paracrine activities by Allerstorfer, S, Sonvilla, G, Fischer, H, Spiegl-Kreinecker, S, Gauglhofer, C, Setinek, U, Czech, T, Marosi, C, Buchroithner, J, Pichler, J, Silye, R, Mohr, T, Holzmann, K, Grasl-Kraupp, B, Marian, B, Grusch, M, Fischer, J, Micksche, M, Berger, W

“…Fibroblast growth factor 5 (FGF5) is widely expressed in embryonic but scarcely in adult tissues. Here we report simultaneous overexpression of FGF5 and its…”
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Cellular functions of vaults and their involvement in multidrug resistance by Steiner, E, Holzmann, K, Elbling, L, Micksche, M, Berger, W

“…Vaults are evolutionary highly conserved ribonucleoprotein (RNP) particles with a hollow barrel-like structure. They are 41 x 73 nm in size and are composed of…”
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Anticancer effects of zoledronic acid against human osteosarcoma cells by Kubista, B., Trieb, K., Sevelda, F., Toma, C., Arrich, F., Heffeter, P., Elbling, L., Sutterlüty, H., Scotlandi, K., Kotz, R., Micksche, M., Berger, W.

“…Based on neoadjuvant chemotherapy, the prognosis of osteosarcoma patients has improved dramatically. However, due to therapy resistance in patient subgroups,…”
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Probiotic, as well as conventional yogurt, can enhance the stimulated production of proinflammatory cytokines by Meyer, A.L, Elmadfa, I, Herbacek, I, Micksche, M

“…Lactic acid bacteria have been shown to stimulate the secretion of cytokines by lymphocytes and monocytes in a strain-dependent manner. Therefore, in this…”
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Multidrug-resistant cancer cells are preferential targets of the new antineoplastic lanthanum compound KP772 (FFC24) by Heffeter, P., Jakupec, M.A., Körner, W., Chiba, P., Pirker, C., Dornetshuber, R., Elbling, L., Sutterlüty, H., Micksche, M., Keppler, B.K., Berger, W.

“…Recently, we have introduced [tris(1,10-phenanthroline)lanthanum(III)] trithiocyanate (KP772, FFC24) as a new lanthanum compound which has promising anticancer…”
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Intrinsic and acquired forms of resistance against the anticancer ruthenium compound KP1019 [indazolium trans-[tetrachlorobis(1H-indazole)ruthenate (III)] (FFC14A) by Heffeter, P, Pongratz, M, Steiner, E, Chiba, P, Jakupec, M A, Elbling, L, Marian, B, Körner, W, Sevelda, F, Micksche, M, Keppler, B K, Berger, W

“…KP1019 [indazolium trans-[tetrachlorobis(1H-indazole)ruthenate (III)] (FFC14A) is a metal complex with promising anticancer activity. Since chemoresistance is…”
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Association of microsomal epoxide hydrolase polymorphisms and lung cancer risk by GSUR, A, ZIDEK, T, TRIEB, K, VUTUC, C, MICKSCHE, M, SCHNATTINGER, K, FEIK, E, HAIDINGER, G, HOLLAUS, P, MOHN-STAUDNER, A, ARMBRUSTER, C, MADERSBACHERS, S, SCHATZL, G

“…Microsomal epoxide hydrolase (mEH) plays a dual role in the detoxification and activation of tobacco procarcinogens. Two polymorphisms affecting enzyme…”
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New cellular tools reveal complex epithelial-mesenchymal interactions in hepatocarcinogenesis by Sagmeister, S, Eisenbauer, M, Pirker, C, Mohr, T, Holzmann, K, Zwickl, H, Bichler, C, Kandioler, D, Wrba, F, Mikulits, W, Gerner, C, Shehata, M, Majdic, O, Streubel, B, Berger, W, Micksche, M, Zatloukal, K, Schulte-Hermann, R, Grasl-Kraupp, B

“…To enable detailed analyses of cell interactions in tumour development, new epithelial and mesenchymal cell lines were established from human hepatocellular…”
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Dynamics of chemosensitivity and chromosomal instability in recurrent glioblastoma by SPIEGL -KREINECKER, S, PIRKER, C, MAROSI, C, BUCHROITHNER, J, PICHLER, J, SILYE, R, FISCHER, J, MICKSCHE, M, BERGER, W

“…Glioblastoma multiforme is characterised by invasive growth and frequent recurrence. Here, we have analysed chromosomal changes in comparison to tumour cell…”
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Ribonucleotide reductase as one important target of [Tris(1,10-phenanthroline)lanthanum(III)] trithiocyanate (KP772) by Heffeter, P, Popovic-Bijelic, A, Saiko, P, Dornetshuber, R, Jungwirth, U, Voevodskaya, N, Biglino, D, Jakupec, M A, Elbling, L, Micksche, M, Szekeres, T, Keppler, B K, Gräslund, A, Berger, W

“…KP772 is a new lanthanum complex containing three 1,10-phenathroline molecules. Recently, we have demonstrated that the promising in vitro and in vivo…”
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Daily intake of probiotic as well as conventional yogurt has a stimulating effect on cellular immunity in young healthy women by Meyer, Alexa L, Micksche, Michael, Herbacek, Irene, Elmadfa, Ibrahim

“…The aim of this work was to study the effects of daily yogurt consumption on the cellular immunity of young healthy women and to compare a conventional with a…”
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O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients by Spiegl-Kreinecker, Sabine, Pirker, Christine, Filipits, Martin, Lötsch, Daniela, Buchroithner, Johanna, Pichler, Josef, Silye, Rene, Weis, Serge, Micksche, Michael, Fischer, Johannes, Berger, Walter

“…O(6)-Methylguanine DNA methyltransferase (MGMT) is implicated as a major predictive factor for treatment response to alkylating agents including temozolomide…”
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Hyperthermia increases the susceptibility of chondro- and osteosarcoma cells to natural killer cell-mediated lysis by Kubista, B, Trieb, K, Blahovec, H, Kotz, R, Micksche, M

“…As an adjuvant to chemotherapy hyperthermia has proven to be successful as a treatment for osteo- and chondrosarcoma patients. The aim of this study was to…”
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Effect of granulocyte-macrophage colony-stimulating factor on natural-killer cell mediated cytotoxicity by Kubista, B, Trieb, K, Herbacek, I, Micksche, M

“…Previous studies demonstrated an enhancing effect of granulocyte-macrophage colony-stimulating-factor (GM-CSF) on natural cytotoxicity. It was the aim of this…”
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150 Induction of endoplasmic reticulum stress by the novel anti-cancer compound KP46 and synergism with proteasome inhibition by Gojo, J, Jungwirth, U, Heffeter, P, Atil, B, Micksche, M, Keppler, B.K

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Prostate cancer in Austria: impact of prostate-specific antigen test on incidence and mortality by Vutuc, C, Waldhoer, T, Madersbacher, S, Micksche, M, Haidinger, G

“…The aim of the study was to assess the impact of prostate-specific antigen (PSA) testing on prostate cancer mortality in Austria. A join-point regression model…”
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Response to Comments on: Recommendations on colorectal cancer (CRC) screening in the European Union. Advisory Committee on Cancer Prevention. Eur J Cancer 2000, 36, 1473–1478 by Lynge, E., Micksche, M.

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Expression of the small heat shock protein HSP 27 in developing human skin by JANTSCHITSCH, C, KINDAS-MÜGGE, I, METZE, D, AMANN, G, MICKSCHE, M, TRAUTINGER, F

“…The 27 kDa heat shock protein (HSP 27) is expressed in keratinocytes of the upper epidermal layers, and recent evidence suggests that this protein is involved…”
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Randomised study using IFN-alpha versus IFN-alpha plus coumarin and cimetidine for treatment of advanced renal cell cancer by Sagaster, P, Micksche, M, Flamm, J, Ludwig, H

“…Treatment results in patients with metastatic renal cell cancer (RCC) are still extremely unsatisfactory. Rates of response to IFN-alpha monotherapy and/or…”
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