Search Results - "Michnoff, Carolyn"
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genome-wide RNAi screen for Wnt/β-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer
Published in Proceedings of the National Academy of Sciences - PNAS (15-07-2008)“…The Wnt family of secreted proteins coordinate cell fate decision-making in a broad range of developmental and homeostatic contexts. Corruption of Wnt signal…”
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Synthetic lethal screen identification of chemosensitizer loci in cancer cells
Published in Nature (12-04-2007)“…Abundant evidence suggests that a unifying principle governing the molecular pathology of cancer is the co-dependent aberrant regulation of core machinery…”
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High-throughput Screening for Potent and Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase
Published in The Journal of biological chemistry (10-06-2005)“…Plasmodium falciparum is the causative agent of the most serious and fatal malarial infections, and it has developed resistance to commonly employed…”
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Impaired Cued and Contextual Memory in NPAS2-Deficient Mice
Published in Science (American Association for the Advancement of Science) (23-06-2000)“…Neuronal PAS domain protein 2 (NPAS2) is a basic helix-loop-helix (bHLH) PAS domain transcription factor expressed in multiple regions of the vertebrate brain…”
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PAS Kinase: An Evolutionarily Conserved PAS Domain-Regulated Serine/Threonine Kinase
Published in Proceedings of the National Academy of Sciences - PNAS (31-07-2001)“…PAS domains regulate the function of many intracellular signaling pathways in response to both extrinsic and intrinsic stimuli. PAS domain-regulated histidine…”
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A genome-wide RNAi screen for Wnt/[beta]-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer
Published in Proceedings of the National Academy of Sciences - PNAS (15-07-2008)“…The Wnt family of secreted proteins coordinate cell fate decision-making in a broad range of developmental and homeostatic contexts. Corruption of Wnt signal…”
Get full text
Journal Article -
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A genome-wide RNAi screen for Wnt/b-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer
Published in Proceedings of the National Academy of Sciences - PNAS (01-07-2008)“…The Wnt family of secreted proteins coordinate cell fate decision-making in a broad range of developmental and homeostatic contexts. Corruption of Wnt signal…”
Get full text
Journal Article -
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High-throughput screen for small molecule inhibitors of Mint1-PDZ domains
Published in Assay and drug development technologies (01-12-2007)“…Several hundred PDZ (postsynaptic density-95, Drosophila disks-large, ZO-1) domain-containing proteins have been identified in the human genome. PDZ domains…”
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Kinetics of adenosine 3':5'-monophosphate-dependent protein kinase activation and inhibition of thymidine incorporation into DNA in P1798 lymphosarcoma cells
Published in Cancer research (Chicago, Ill.) (01-08-1983)“…The kinetics for activation of the cyclic adenosine 3':5'-monophosphate (cyclic AMP)-dependent protein kinase (PKA) and thymidine incorporation into DNA was…”
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Mutations within the NH2-terminal transmembrane domain of membrane immunoglobulin (Ig) M alters Ig alpha and Ig beta association and signal transduction
Published in The Journal of biological chemistry (30-09-1994)“…Potentiation of initial signal transduction events through the cross-linking of the B cell antigen receptor complex appears to be dependent upon the…”
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Multiple B29 containing complexes on murine B lymphocytes. Common and stage-restricted Ig-associated polypeptide chains
Published in The Journal of immunology (1950) (15-03-1993)“…The B29 gene is specifically expressed in all cells of the B lymphocyte lineage, and the B29 protein is disulfide-linked to the protein product of at least one…”
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The Cell-Specific Elastase I Enhancer Comprises Two Domains
Published in Molecular and cellular biology (01-02-1988)“…Two separate domains within the 134-base-pair rat elastase I enhancer and a third domain at the enhancer-promoter boundary are required for selective…”
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Calcium-dependent muscle contraction in obliquely striated Ascaris suum muscle
Published in Comparative biochemistry and physiology. B, Comparative biochemistry (1985)“…The regulatory proteins of Ascaris suum striated skeletal muscle were partially purified and characterized. A tropomyosin isoform (Mr 41K) and three troponin…”
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Activation of cyclic AMP-dependent protein kinase by epinephrine in proliferating lymphoid cells
Published in Archives of biochemistry and biophysics (01-04-1982)Get more information
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