Search Results - "Michniak, Bozena B."

Polymeric nanoparticles-based topical delivery systems for the treatment of dermatological diseases by Zhang, Zheng, Tsai, Pei-Chin, Ramezanli, Tannaz, Michniak-Kohn, Bozena B.

“…Human skin not only functions as a permeation barrier (mainly because of the stratum corneum layer) but also provides a unique delivery pathway for therapeutic…”
Get full text

Deodorants and antiperspirants: identification of new strategies and perspectives to prevent and control malodor and sweat of the body by Oliveira, Erika C. V. de, Salvador, Danielle S., Holsback, Valéria, Shultz, Jemima D., Michniak‐Kohn, Bozena B., Leonardi, Gislaine R.

“…Excessive sweating and body odors in many cultures can cause negative perceptions of an individual and in many cases is related to poor hygiene. Personal…”
Get full text

The Contest of Nanoparticles: Searching for the Most Effective Topical Delivery of Corticosteroids by Kalvodová, Aneta, Dvořáková, Kristýna, Petrová, Eliška, Michniak-Kohn, Bozena B, Zbytovská, Jarmila

“…Owing to their complicated pathophysiology, the treatment of skin diseases necessitates a complex approach. Conventional treatment using topical…”
Get full text

Enhanced Transdermal Delivery of Concentrated Capsaicin from Chili Extract-Loaded Lipid Nanoparticles with Reduced Skin Irritation by Anantaworasakul, Phunsuk, Chaiyana, Wantida, Michniak-Kohn, Bozena B, Rungseevijitprapa, Wandee, Ampasavate, Chadarat

“…The aim of this study was to develop lipid-based nanoparticles that entrapped a high concentration of capsaicin (0.25%) from a capsicum oleoresin extract. The…”
Get full text

Tissue engineered human skin equivalents by Zhang, Zheng, Michniak-Kohn, Bozena B

“…Human skin not only serves as an important barrier against the penetration of exogenous substances into the body, but also provides a potential avenue for the…”
Get full text

Anti-Melanogenic Mechanism of Tetrahydrocurcumin and Enhancing Its Topical Delivery Efficacy Using a Lecithin-Based Nanoemulsion by Tang, Xudong, Dong, Qiaoru, Li, Jun, Li, Fang, Michniak-Kohn, Bozena B., Zhao, Denggao, Ho, Chi-Tang, Huang, Qingrong

“…Tetrahydrocurcumin (THC) has been well known for its superior antioxidant properties. Therefore, it is speculated that it might be effective to relieve…”
Get full text

Pediatric Tuberculosis Management: A Global Challenge or Breakthrough? by Maphalle, Lehlogonolo N. F, Michniak-Kohn, Bozena B, Ogunrombi, Modupe O, Adeleke, Oluwatoyin A

“…Managing pediatric tuberculosis (TB) remains a public health problem requiring urgent and long-lasting solutions as TB is one of the top ten causes of ill…”
Get full text

Expert Systems for Predicting the Bioavailability of Sun Filters in Cosmetic Products, Software vs. Expert Formulator: The Benzophenone-3 Case by Baldisserotto, Anna, Baldini, Erika, Ravarotto, Sara, Cesa, Elena, De Lucia, Daniela, Durini, Elisa, Vertuani, Silvia, Manfredini, Stefano, Michniak-Kohn, Bozena B

“…There are only a limited number of molecules in a cosmetic formulation, which can passively cross the stratum corneum and be absorbed into the skin layers…”
Get full text

Enhanced iontophoretic delivery of buspirone hydrochloride across human skin using chemical enhancers by Meidan, Victor M, Al-Khalili, Mohammad, Michniak, Bozena B

“…Buspirone hydrochloride (BH) is a structurally and pharmacologically unique anxiolytic that is used to treat a variety of different anxiety conditions. The…”
Get full text

Transdermal and Buccal Delivery of Methylxanthines Through Human Tissue In Vitro by Thakur, Rashmi A., Michniak, Bozena B., Meidan, Victor M.

“…ABSTRACT We examined the in vitro permeation of central nervous stimulants-caffeine, theophylline, and theobromine across human skin with the aid of six…”
Get full text

Investigation of microemulsion and microemulsion gel formulations for dermal delivery of clotrimazole by Zhang, Ji, Michniak-Kohn, Bozena B.

“…[Display omitted] Dermal delivery of hydrophobic drugs by microemulsion (ME) formulations and effect from ME microstructures were studied. Anti-fungal drug,…”
Get full text

Transfollicular drug delivery—Is it a reality? by Meidan, Victor M., Bonner, Michael C., Michniak, Bozena B.

“…Once regarded as merely evolutionary remnants, the hair follicles and sebaceous glands are increasingly recognised as potentially significant elements in the…”
Get full text

Polymeric nanospheres for topical delivery of vitamin D3 by Ramezanli, Tannaz, Kilfoyle, Brian E., Zhang, Zheng, Michniak-Kohn, Bozena B.

“…[Display omitted] This study investigates the potential application of polymeric nanospheres (known as TyroSpheres) as a formulation carrier for topical…”
Get full text

Development and Characterization of a Topical Gel Formulation of Adapalene-TyroSpheres and Assessment of Its Clinical Efficacy by Ramezanli, Tannaz, Michniak-Kohn, Bozena B

“…In this study we aimed to develop a semi-solid formulation of polymeric nanoparticles loaded with adapalene to enhance the efficacy and improve the skin…”
Get full text

Development and Characterization of Polymeric Nanoparticle-Based Formulation of Adapalene for Topical Acne Therapy by Ramezanli, Tannaz, Zhang, Zheng, Michniak-Kohn, Bozena B

“…Abstract The purpose of this study is to develop a new formulation of adapalene for the topical treatment of acne. We investigated applicability of polymeric…”
Get full text

Percutaneous penetration enhancers: local versus transdermal activity by Asbill, Charles S, Michniak, Bozena B

“…The stratum corneum, poses a formidable challenge to formulators of drug delivery systems. Several approaches have been utilized to facilitate entry of drugs…”
Get full text

Development of paclitaxel-TyroSpheres for topical skin treatment by Kilfoyle, Brian E., Sheihet, Larisa, Zhang, Zheng, Laohoo, Marissa, Kohn, Joachim, Michniak-Kohn, Bozena B.

“…A potential topical psoriasis therapy has been developed consisting of tyrosine-derived nanospheres (TyroSpheres) with encapsulated anti-proliferative…”
Get full text

Isoniazid-loaded orodispersible strips: Methodical design, optimization and in vitro-in silico characterization by Adeleke, Oluwatoyin A., Tsai, Pei-Chin, Karry, Krizia M., Monama, Nkwe O., Michniak-Kohn, Bozena B.

“…[Display omitted] Drug treatment remains the most effective global approach to managing and preventing tuberculosis. This work focuses on formulating and…”
Get full text

Infrared Kinetic/Structural Studies of Barrier Reformation in Intact Stratum Corneum following Thermal Perturbation by Pensack, Ryan D., Michniak, Bozena B., Moore, David J., Mendelsohn, Richard

“…Stratum corneum, the outermost layer of the epidermis, constitutes the main barrier to permeability in skin. As such, it has been the target of many approaches…”
Get full text

The effects of terpene enhancers on the percutaneous permeation of drugs with different lipophilicities by El-Kattan, Ayman F., Asbill, Charles S., Kim, Nanhye, Michniak, Bozena B.

“…Four model drugs were selected based on their lipophilicity denoted as log P (nicardipine hydrochloride log P −0.99±0.1, hydrocortisone log P 1.43±0.47,…”
Get full text