Search Results - "Michki, Nigel"

Dynamic Hippo pathway activity underlies mesenchymal differentiation during lung alveolar morphogenesis by Chaudhry, Fatima N, Michki, Nigel S, Shirmer, Dain L, Mcgrath-Morrow, Sharon, Young, Lisa R, Frank, David B, Zepp, Jarod A

“…Alveologenesis, the final stage in lung development, substantially remodels the distal lung, expanding the alveolar surface area for efficient gas exchange…”
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DNA methyltransferase inhibition induces dynamic gene expression changes in lung CD4+ T cells of neonatal mice with E. coli pneumonia by Michki, Nigel S., Ndeh, Roland, Helmin, Kathryn A., Singer, Benjamin D., McGrath-Morrow, Sharon A.

“…Bacterial pulmonary infections are a major cause of morbidity and mortality in neonates, with less severity in older children. Previous studies demonstrated…”
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Cellular and molecular dynamics in the lungs of neonatal and juvenile mice in response to E. coli by McGrath-Morrow, Sharon A, Venezia, Jarrett, Ndeh, Roland, Michki, Nigel, Perez, Javier, Singer, Benjamin David, Cimbro, Raffaello, Soloski, Mark, Scott, Alan L

“…Bacterial pneumonia in neonates can cause significant morbidity and mortality when compared to other childhood age groups. To understand the immune mechanisms…”
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The molecular landscape of neural differentiation in the developing Drosophila brain revealed by targeted scRNA-seq and multi-informatic analysis by Michki, Nigel S., Li, Ye, Sanjasaz, Kayvon, Zhao, Yimeng, Shen, Fred Y., Walker, Logan A., Cao, Wenjia, Lee, Cheng-Yu, Cai, Dawen

“…The Drosophila type II neuroblast lineages present an attractive model to investigate the neurogenesis and differentiation process as they adapt to a process…”
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Transcriptional profiling of peripheral blood mononuclear cells identifies inflammatory phenotypes in Ataxia Telangiectasia by Michki, Nigel S, Singer, Benjamin D, Perez, Javier V, Thomas, Aaron J, Natale, Valerie, Helmin, Kathryn A, Wright, Jennifer, Cheng, Leon, Young, Lisa R, Lederman, Howard M, McGrath-Morrow, Sharon A

“…Ataxia telangiectasia (A-T) is an autosomal recessive neurodegenerative disease with widespread systemic manifestations and marked variability in clinical…”
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CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth by Chandrasekaran, Prashant, Negretti, Nicholas M, Sivakumar, Aravind, Liberti, Derek C, Wen, Hongbo, Peers de Nieuwburgh, Maureen, Wang, Joanna Y, Michki, Nigel S, Chaudhry, Fatima N, Kaur, Sukhmani, Lu, MinQi, Jin, Annabelle, Zepp, Jarod A, Young, Lisa R, Sucre, Jennifer M S, Frank, David B

“…There is a growing amount of data uncovering the cellular diversity of the pulmonary circulation and mechanisms governing vascular repair after injury…”
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nGauge: Integrated and Extensible Neuron Morphology Analysis in Python by Walker, Logan A., Williams, Jennifer S., Li, Ye, Roossien, Douglas H., Lee, Wei Jie, Michki, Nigel S., Cai, Dawen

“…The study of neuron morphology requires robust and comprehensive methods to quantify the differences between neurons of different subtypes and animal species…”
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Bitbow Enables Highly Efficient Neuronal Lineage Tracing and Morphology Reconstruction in Single Drosophila Brains by Li, Ye, Walker, Logan A, Zhao, Yimeng, Edwards, Erica M, Michki, Nigel S, Cheng, Hon Pong Jimmy, Ghazzi, Marya, Chen, Tiffany Y, Chen, Maggie, Roossien, Douglas H, Cai, Dawen

“…Identifying the cellular origins and mapping the dendritic and axonal arbors of neurons have been century old quests to understand the heterogeneity among…”
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Identification of Neuronal Lineages in the Drosophila Peripheral Nervous System with a “Digital” Multi-spectral Lineage Tracing System by Veling, Macy W., Li, Ye, Veling, Mike T., Litts, Christopher, Michki, Nigel, Liu, Hao, Ye, Bing, Cai, Dawen

“…Elucidating cell lineages provides crucial understanding of development. Recently developed sequencing-based techniques enhance the scale of lineage tracing…”
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Escaping the Water Cage: Protein Intramolecular Vibrations and the Dynamical Transition by Xu, Mengyang, Niessen, Katherine A., Deng, Yanting, Michki, Nigel S., Markelz, Andrea G.

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The Developmental Landscape of Neurogenesis in Drosophila melanogaster Revealed Using Targeted Single-Cell RNA-Sequencing and a Multi-Informatic Analysis Paradigm by Michki, Nigel S

“…The Drosophila type-II neuroblast lineages present an attractive model to investigate the neurogenesis and differentiation process as they adapt to a process…”
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The Effect of the Protein Dynamical Transition on Intramolecular Vibrations by Xu, Mengyang, Niessen, Katherine A., Deng, Yanting, Michki, Nigel S., Snell, Edward H., Markelz, Andrea G.

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Anisotropic absorption measurements reveal protein dynamical transition in intramolecular vibrations by Mengyang Xu, Niessen, Katherine, Michki, Nigel, Yanting Deng, Snell, Edward, Markelz, A. G.

“…Modeling has predicted that intramolecular structural vibrations enables proteins to access functionally important structural change. We show that the…”
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