Search Results - "Michielsen, Adriana J"

Tumour tissue microenvironment can inhibit dendritic cell maturation in colorectal cancer by Michielsen, Adriana J, Hogan, Andrew E, Marry, Joseph, Tosetto, Miriam, Cox, Fionnuala, Hyland, John M, Sheahan, Kieran D, O'Donoghue, Diarmuid P, Mulcahy, Hugh E, Ryan, Elizabeth J, O'Sullivan, Jacintha N

“…Inflammatory mediators in the tumour microenvironment promote tumour growth, vascular development and enable evasion of anti-tumour immune responses, by…”
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pSTAT3 Levels Have Divergent Expression Patterns and Associations with Survival in Squamous Cell Carcinoma and Adenocarcinoma of the Oesophagus by O' Sullivan, Katie E, Michielsen, Adriana J, O' Regan, Esther, Cathcart, Mary C, Moore, Gillian, Breen, Eamon, Segurado, Ricardo, Reynolds, John V, Lysaght, Joanne, O' Sullivan, Jacintha

“…Signal transducers and activator of transcription (STAT)-3 is activated in cancers, where it promotes growth, inflammation, angiogenesis, and inhibits…”
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Tumor conditioned media from colorectal cancer patients inhibits dendritic cell maturation by Michielsen, Adriana J., O'Sullivan, Jacintha N., Ryan, Elizabeth J.

“…Tumors inhibit dendritic cell maturation and function in order to evade host immunity. We showed that conditioned media from tumor explant tissue, taken from…”
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Characterising the prognostic potential of HLA-DR during colorectal cancer development by Dunne, Margaret R., Phelan, James J., Michielsen, Adriana J., Maguire, Aoife A., Dunne, Cara, Martin, Petra, Noonan, Sinead, Tosetto, Miriam, Geraghty, Robert, Fennelly, David, Sheahan, Kieran, Ryan, Elizabeth J., O’Sullivan, Jacintha

“…HLA-DR, an MHC class II molecule that mediates antigen presentation, is a favourable prognostic indicator in colorectal cancer (CRC). However, the dynamics and…”
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Analysis of Polo-like kinase Cdc5 in the meiosis recombination checkpoint by Iacovella, Maria G., Daly, Catherine N., Kelly, Jamie-Sioux, Michielsen, Adriana J., Clyne, Rosemary K.

“…In meiosis, accumulation of recombination intermediates or defects in chromosome synapsis trigger checkpoint-mediated arrest in prophase I.  Such 'checkpoints'…”
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HLA-DR expression in tumor epithelium is an independent prognostic indicator in esophageal adenocarcinoma patients by Dunne, Margaret R., Michielsen, Adriana J., O’Sullivan, Katie E., Cathcart, Mary Clare, Feighery, Ronan, Doyle, Brendan, Watson, Jenny A., O’Farrell, Naoimh J., Ravi, Narayanasamy, Kay, Elaine, Reynolds, John V., Ryan, Elizabeth J., O’Sullivan, Jacintha

“…Esophageal adenocarcinoma (EAC) is an aggressive cancer with poor prognosis, and incidence is increasing rapidly in the Western world. Measurement of immune…”
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Inhibition of dendritic cell maturation by the tumor microenvironment correlates with the survival of colorectal cancer patients following bevacizumab treatment by Michielsen, Adriana J, Noonan, Sinead, Martin, Petra, Tosetto, Miriam, Marry, Joseph, Biniecka, Monika, Maguire, Aoife A, Hyland, John M, Sheahan, Kieran D, O'Donoghue, Diarmuid P, Mulcahy, Hugh E, Fennelly, David, Ryan, Elizabeth J, O'Sullivan, Jacintha N

“…Development of bevacizumab has improved survival in colorectal cancer, however, currently there are no biomarkers that predict response to bevacizumab and it…”
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Dendritic cell inhibition correlates with survival of colorectal cancer patients on bevacizumab treatment by Michielsen, Adriana J., Ryan, Elizabeth J., O'Sullivan, Jacintha N.

“…We demonstrated that dendritic cell (DC) inhibition by tumor-conditioned media in the presence or absence of bevacizumab correlates with colorectal cancer…”
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Dendritic cell inhibition correlates with survival of colorectal cancer patients on bevacizumab treatment by Adriana J. Michielsen, Jacintha N. O’Sullivan, Elizabeth J. Ryan

“…We demonstrated that dendritic cell (DC) inhibition by tumor-conditioned media in the presence or absence of bevacizumab correlates with colorectal cancer…”
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