Search Results - "Michels, L."

Deep Aramaic: Towards a synthetic data paradigm enabling machine learning in epigraphy by Aioanei, Andrei C, Hunziker-Rodewald, Regine R, Klein, Konstantin M, Michels, Dominik L

“…Epigraphy is witnessing a growing integration of artificial intelligence, notably through its subfield of machine learning (ML), especially in tasks like…”
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Nasal Administration of Cationic Nanoemulsions as CD73-siRNA Delivery System for Glioblastoma Treatment: a New Therapeutical Approach by Azambuja, J. H., Schuh, R. S., Michels, L. R., Gelsleichter, N. E., Beckenkamp, L. R., Iser, I. C., Lenz, G. S., de Oliveira, F. H., Venturin, G., Greggio, S., daCosta, J. C., Wink, M. R., Sevigny, J., Stefani, M. A., Battastini, A. M. O., Teixeira, H. F., Braganhol, E.

“…Glioblastoma is the most devastating primary brain tumor. Effective therapies are not available, mainly due to high tumor heterogeneity, chemoresistance, and…”
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Intercalation and Retention of Carbon Dioxide in a Smectite Clay promoted by Interlayer Cations by Michels, L., Fossum, J. O., Rozynek, Z., Hemmen, H., Rustenberg, K., Sobas, P. A., Kalantzopoulos, G. N., Knudsen, K. D., Janek, M., Plivelic, T. S., da Silva, G. J.

“…A good material for CO 2 capture should possess some specific properties: (i) a large effective surface area with good adsorption capacity, (ii) selectivity…”
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Synthetic data at scale: a development model to efficiently leverage machine learning in agriculture by Klein, Jonathan, Waller, Rebekah, Pirk, Sören, Pałubicki, Wojtek, Tester, Mark, Michels, Dominik L

“…The rise of artificial intelligence (AI) and in particular modern machine learning (ML) algorithms during the last decade has been met with great interest in…”
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Voxel-Based Morphometry-from Hype to Hope. A Study on Hippocampal Atrophy in Mesial Temporal Lobe Epilepsy by Riederer, F, Seiger, R, Lanzenberger, R, Pataraia, E, Kasprian, G, Michels, L, Beiersdorf, J, Kollias, S, Czech, T, Hainfellner, J, Baumgartner, C

“…Automated volumetry of the hippocampus is considered useful to assist the diagnosis of hippocampal sclerosis in temporal lobe epilepsy. However, voxel-based…”
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Effect of the isotiazole adjuvants in combination with cisplatin in chemotherapy of neuroepithelial tumors: experimental results and modeling by Potkin, Vladimir, Pushkarchuk, Aliaxandr, Zamaro, Alexandra, Zhou, Hongwei, Kilin, Sergey, Petkevich, Sergey, Kolesnik, Irina, Michels, Dominik L., Lyakhov, Dmitry A., Kulchitsky, Vladimir A.

“…Chemotherapy is one of the main treatment options for cancer, but it is usually accompanied with negative side effects. The classical drugs combination with…”
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Impact of the CYP2D6 Genotype on the Clinical Effects of Metoprolol: A Prospective Longitudinal Study by Rau, T, Wuttke, H, Michels, LM, Werner, U, Bergmann, K, Kreft, M, Fromm, MF, Eschenhagen, T

“…After administration of metoprolol, plasma concentrations of the drug are markedly higher in CYP2D6 poor metabolizers (PMs) than in non‐PMs. In a prospective…”
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Blockade of CD73 delays glioblastoma growth by modulating the immune environment by Azambuja, J. H., Schuh, R. S., Michels, L. R., Iser, I. C., Beckenkamp, L. R., Roliano, G. G., Lenz, G. S., Scholl, J. N., Sévigny, J., Wink, M. R., Stefani, M. A., Battastini, A. M. O., Figueiró, F., Teixeira, H. F., Braganhol, E.

“…Immunotherapy as an approach for cancer treatment is clinically promising. CD73, which is the enzyme that produces extracellular adenosine, favors cancer…”
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Age dependent electroencephalographic changes in attention-deficit/hyperactivity disorder (ADHD) by Poil, S.-S, Bollmann, S, Ghisleni, C, O’Gorman, R.L, Klaver, P, Ball, J, Eich-Höchli, D, Brandeis, D, Michels, L

“…Highlights • ADHD effects on resting (eyes-closed) EEG strongly depend on age and frequency. • Support vector machine classification of ADHD adults versus…”
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Developmental changes in gamma-aminobutyric acid levels in attention-deficit/hyperactivity disorder by Bollmann, S, Ghisleni, C, Poil, S-S, Martin, E, Ball, J, Eich-Höchli, D, Edden, R A E, Klaver, P, Michels, L, Brandeis, D, O'Gorman, R L

“…While the neurobiological basis and developmental course of attention-deficit/hyperactivity disorder (ADHD) have not yet been fully established, an imbalance…”
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Alkaloid-Based Isoxazolylureas: Synthesis and Effect in Combination with Anticancer Drugs on C6 Rat Glioma Model Cells by Mukusheva, Gulim K, Jalmakhanbetova, Roza I, Shaibek, Altynay Zh, Nurmaganbetova, Manshuk S, Zhasymbekova, Aigerym R, Nurkenov, Oralgazy A, Akishina, Ekaterina A, Kolesnik, Irina A, Dikusar, Evgenij A, Terpinskaya, Tatiana I, Kulchitsky, Vladimir A, Potkin, Vladimir I, Pushkarchuk, Alexander L, Lyakhov, Dmitry A, Michels, Dominik L

“…Alkaloid-based urea derivatives were produced with high yield through the reaction of anabasine and cytisine with isoxazolylphenylcarbamates in boiling…”
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Helical surfaces with a constant ratio of principal curvatures by Liu, Yang, Pirahmad, Olimjoni, Wang, Hui, Michels, Dominik L., Pottmann, Helmut

“…We determine all helical surfaces in three-dimensional Euclidean space which possess a constant ratio a : = κ 1 / κ 2 of principal curvatures (CRPC surfaces),…”
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Management practices on organic and conventional dairy herds in Minnesota by Sorge, U S, Moon, R, Wolff, L J, Michels, L, Schroth, S, Kelton, D F, Heins, B

“…The objective of this study was to describe and compare husbandry practices on organic and conventional dairy farms of similar sizes in Minnesota. Organic…”
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The Role of Boron in Low Copper Spheroidal Graphite Irons by Bugten, A. V., Michels, L., Brurok, R. B., Hartung, C., Ott, E., Vines, L., Li, Y., Arnberg, L., Di Sabatino, M.

“…The effects of boron at concentrations ranging from 5 to 525 ppm in low copper spheroidal graphite iron (SGI) has been studied. At 130 to 140 ppm, no…”
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CD73 as a target to improve temozolomide chemotherapy effect in glioblastoma preclinical model by Azambuja, J. H., Schuh, R. S., Michels, L. R., Gelsleichter, N. E., Beckenkamp, L. R., Lenz, G. S., de Oliveira, F. H., Wink, M. R., Stefani, M. A., Battastini, A. M. O., Teixeira, H. F., Braganhol, E.

“…Glioblastoma is the most devastating primary brain tumor and effective therapies are not available. Treatment is based on surgery followed by radio and…”
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The Impact of Thermal History on Water Adsorption in a Synthetic Nanolayered Silicate with Intercalated Li+ or Na+ by Michels, L, da Fonseca, C. L. S, Méheust, Y, Altoé, M. A. S, dos Santos, E. C, Grassi, G, Droppa, R, Knudsen, K. D, Cavalcanti, L. P, Hunvik, K. W. B, Fossum, J. O, da Silva, G. J, Bordallo, H. N

“…For applications benefitting from the swelling properties of nanolayered silicates (clay minerals), it is of paramount importance to understand the hysteresis…”
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The pH influence on the intercalation of the bioactive agent ciprofloxacin in fluorohectorite by dos Santos, E.C., Gates, W.P., Michels, L., Juranyi, F., Mikkelsen, A., da Silva, G.J., Fossum, J.O., Bordallo, H.N.

“…Biocompatible encapsulated drug delivery materials are highly desired as they provide for controlled release of bioactive agents, thereby improving the…”
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Effect of Holding Time on Populations of Microparticles in Spheroidal Graphite Irons by Michels, L., Pires, A. J. F., Ribeiro, C. A. S., Kroka, B., Hoel, E. G., Ott, E., Hartung, C.

“…Non-metallic microparticles in spheroidal graphite irons are a product of the inoculation and the Mg-treatment of the liquid melt. Besides the influence on the…”
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Ciprofloxacin intercalated in fluorohectorite clay: identical pure drug activity and toxicity with higher adsorption and controlled release rate by dos Santos, E. C, Rozynek, Z, Hansen, E. L, Hartmann-Petersen, R, Klitgaard, R. N, Lbner-Olesen, A, Michels, L, Mikkelsen, A, Plivelic, T. S, Bordallo, H. N, Fossum, J. O

“…Different natural clay minerals, including halloysite, montmorillonite and kaolinite, have been proven to be efficient drug carriers providing for high and…”
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Montanide ISA 71 VG is Advantageous to Freund's Adjuvant in Immunization Against S. aureus Infection of Mice by Klimka, A., Michels, L., Glowalla, E., Tosetti, B., Krönke, M., Krut, O.

“…The enormous capacity of Staphylococcus aureus to acquire antibiotic resistance makes it a permanent task to search for and to develop new anti‐infectives. One…”
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