Search Results - "Michelon, Elisabete"

The Association Between Obesity and the Frailty Syndrome in Older Women: The Women's Health and Aging Studies by Blaum, Caroline S., Xue, Qian Li, Michelon, Elisabete, Semba, Richard D., Fried, Linda P.

“…Objectives: To determine whether obesity is associated with the frailty phenotype and, if so, whether comorbid conditions or inflammatory markers explain this…”
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Pharmacokinetics, safety, and efficacy of an alternative dosing regimen of sasanlimab in participants with advanced NSCLC and other malignancies by Penkov, Konstantin, Bondarenko, Igor, Saenko, Daria Viktorovna, Kulyaba, Yaroslav, Guo, Jun, Gong, Yi, Yamamoto, Noboru, Hotko, Yevhen Stepanovych, Boyko, Vasyl, Fadeeva, Natalya Vladimirovna, Ursol, Grygorii Mykolaiovych, Ahn, Hee Kyung, Kislov, Nikolay Viktorovich, Shen, Chia-I, Davis, Craig, Kowalski, Karey, Michelon, Elisabete, Pavlov, Dmitri, Hirohashi, Tomoko, Cho, Byoung Chul

“…Sasanlimab (PF-06801591), a humanized immunoglobulin G4 monoclonal antibody, binds to programmed cell death protein-1 (PD-1), preventing ligand (PD-L1)…”
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Long-term safety of avelumab first-line (1L) maintenance for advanced urothelial carcinoma (aUC) in the JAVELIN Bladder 100 trial by Bellmunt, Joaquim, Aragon-Ching, Jeanny B., Climent, Miguel Ángel, Sridhar, Srikala S., Powles, Thomas, Cislo, Paul, Michelon, Elisabete, Di Pietro, Alessandra, Grivas, Petros

“…4516 Background: In the phase 3 JAVELIN Bladder 100 trial (NCT02603432), patients (pts) with aUC without progression after 1L platinum-based chemotherapy had…”
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Left Ventricular Ejection Fraction in Patients With Ovarian Cancer Treated With Avelumab, Pegylated Liposomal Doxorubicin, or Both by Bonaca, Marc P, Moslehi, Javid J, Ledermann, Jonathan A, Michelon, Elisabete, Wei, Caimiao, Moran, Michael, Monk, Bradley J, Pujade-Lauraine, Eric

“…Abstract In the phase III JAVELIN Ovarian 200 trial, 566 patients with platinum-resistant/refractory ovarian cancer were randomized 1:1:1 to receive avelumab…”
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Myocarditis Associated with Immune Checkpoint Inhibitors: An Expert Consensus on Data Gaps and a Call to Action by Neilan, Tomas G., Rothenberg, Mace L., Amiri‐Kordestani, Laleh, Sullivan, Ryan J., Steingart, Richard M., Gregory, William, Hariharan, Subramanian, Hammad, Tarek A., Lindenfeld, JoAnn, Murphy, Martin J., Moslehi, Javid J., Abdullah, Hesham, Amiri‐Kordestani, Laleh, Bakker, Cecilia, Boshoff, Chris, Bringhurst, Charlie, Bucktrout, Samantha, Carlin, Kathleen, Caubel, Patrick, Chen, Roland, Chin, Kevin, Chudnovsky, Aleksander, Davis, John, Deutsch, Jonathan, Dixit, Rakesh, Gottfridsson, Christer, Gregory, William, Hammad, Tarek A., Handelsman, Dave, Hariharan, Subramanian, Holmes, William, Honig, Peter, Hugh‐Jones, Charles, Kaufman, Howard, Khan, Nasir, Kozono, David, Kwan, Antonia, Lewis‐Hall, Freda C., Ley‐Acosta, Sergio, Lindenfeld, JoAnn, Michelon, Elisabete, Moslehi, Javid J., Murphy, Martin J., Neilan, Tomas G., Patel, Mayur, Pavlovic, Dejan, Pignatti, Francesco, Potter, Jonathan, Reese, David, Rothenberg, Mace L., Safferman, Allan, Silvester, Eliza, Steingart, Richard M., Sullivan, Ryan J., Zhou, Ming

“…Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape for cancer. Due to the mechanism of action of ICIs, inflammatory reactions against…”
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Avelumab Plus Talazoparib in Patients With Advanced Solid Tumors: The JAVELIN PARP Medley Nonrandomized Controlled Trial by Yap, Timothy A, Bardia, Aditya, Dvorkin, Michael, Galsky, Matthew D, Beck, J Thaddeus, Wise, David R, Karyakin, Oleg, Rubovszky, Gábor, Kislov, Nikolay, Rohrberg, Kristoffer, Joy, Anil Abraham, Telli, Melinda L, Schram, Alison M, Conte, Umberto, Chappey, Colombe, Stewart, Ross, Stypinski, Daria, Michelon, Elisabete, Cesari, Rossano, Konstantinopoulos, Panagiotis A

“…Preclinical data suggest that poly(ADP-ribose) polymerase (PARP) inhibitors have synergistic activity when combined with immune checkpoint inhibitors (ICIs);…”
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Avelumab Plus Axitinib as First-Line Therapy for Advanced Renal Cell Carcinoma: Long-Term Results from the JAVELIN Renal 100 Phase Ib Trial by Larkin, James, Oya, Mototsugu, Martignoni, Marcella, Thistlethwaite, Fiona, Nathan, Paul, Ornstein, Moshe C, Powles, Thomas, Beckermann, Kathryn E, Balar, Arjun V, McDermott, David, Gupta, Sumati, Philips, George K, Gordon, Michael S, Uemura, Hirotsugu, Tomita, Yoshihiko, Wang, Jing, Michelon, Elisabete, di Pietro, Alessandra, Choueiri, Toni K

“…Abstract Background Progression-free survival was significantly longer in patients who received avelumab plus axitinib versus sunitinib as first-line treatment…”
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Incidence of safety events after immune checkpoint inhibitor initiation for advanced-stage non-small-cell lung cancer: a real-world study by Beachler, Daniel C, Lamy, Francois Xavier, Kolitsopoulos, Francesca, Dinh, Jade, Papazian, Anahit, Jamal-Allial, Aziza, Mahmoudpour, Seyed Hamidreza, Michelon, Elisabete, Verpillat, Patrice

“…To describe the incidence of safety events after immune checkpoint inhibitor (ICI) initiation for advanced-stage non-small-cell lung cancer. Retrospective…”
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First-line avelumab plus chemotherapy in patients with advanced solid tumors: results from the phase 1b/2 JAVELIN Chemotherapy Medley study by Wheatley, Duncan A, Berardi, Rossana, Climent Duran, Miguel A, Tomiak, Anna, Greystoke, Alastair P, Joshua, Anthony M, Arkenau, Hendrik-Tobias, Géczi, Lajos, Garcia-Corbacho, Javier, Paz-Ares, Luis G, Hussain, Syed A, Petruželka, Lubos, Delmonte, Angelo, Chappey, Colombe, Masters, Joanna C, Michelon, Elisabete, Murphy, Danielle A, Mwewa, Sandrine, Cesari, Rossano, Doger de Speville, Bernard

“…Chemotherapy can potentially enhance the activity of immune checkpoint inhibitors by promoting immune priming. The phase 1b/2 JAVELIN Chemotherapy Medley trial…”
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Vitamin and Carotenoid Status in Older Women: Associations With the Frailty Syndrome by Michelon, Elisabete, Blaum, Caroline, Semba, Richard D., Xue, Qian-Li, Ricks, Michelle O., Fried, Linda P.

“…Objective. We investigated the relationship of micronutrient deficiencies with the frailty syndrome in older women living in the community. Methods. Frailty…”
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First-line Avelumab plus Chemotherapy in Patients with Advanced Solid Tumors: Results from the Phase Ib/II JAVELIN Chemotherapy Medley Study by Wheatley, Duncan A., Berardi, Rossana, Climent Duran, Miguel A., Tomiak, Anna, Greystoke, Alastair P., Joshua, Anthony M., Arkenau, Hendrik-Tobias, Géczi, Lajos, Corbacho, Javier Garciá, Paz-Ares, Luis G., Hussain, Syed A., Petruželka, Lubos, Delmonte, Angelo, Chappey, Colombe, Masters, Joanna C., Michelon, Elisabete, Murphy, Danielle A., Mwewa, Sandrine, Cesari, Rossano, Doger de Spéville, Bernard

“…Abstract Purpose: Chemotherapy can potentially enhance the activity of immune checkpoint inhibitors by promoting immune priming. The phase Ib/II JAVELIN…”
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