Search Results - "Michelle S. Ginsberg"

Cabozantinib in patients with advanced RET -rearranged non-small-cell lung cancer: an open-label, single-centre, phase 2, single-arm trial by Drilon, Alexander, Dr, Rekhtman, Natasha, PhD, Arcila, Maria, MD, Wang, Lu, PhD, Ni, Andy, PhD, Albano, Melanie, Van Voorthuysen, Martine, Somwar, Romel, PhD, Smith, Roger S, Montecalvo, Joseph, MD, Plodkowski, Andrew, MD, Ginsberg, Michelle S, MD, Riely, Gregory J, PhD, Rudin, Charles M, Prof, Ladanyi, Marc, Prof, Kris, Mark G, Prof

“…Summary Background RET rearrangements are found in 1–2% of non-small-cell lung cancers. Cabozantinib is a multikinase inhibitor with activity against RET that…”
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Lesion-Level Response Dynamics to Programmed Cell Death Protein (PD-1) Blockade by Osorio, Juan C, Arbour, Kathryn C, Le, Dung T, Durham, Jennifer N, Plodkowski, Andrew J, Halpenny, Darragh F, Ginsberg, Michelle S, Sawan, Peter, Crompton, Joseph G, Yu, Helena A, Namakydoust, Azadeh, Nabet, Barzin Y, Chaft, Jamie E, Riely, Gregory J, Rizvi, Hira, Diaz, Jr, Luis A, Hellmann, Matthew D

“…Response to programmed cell death protein 1 (PD-1) blockade is often conceptualized as resulting from reinvigoration of tumor-infiltrating lymphocytes…”
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Intra- and interobserver variability in CT measurements in oncology by McErlean, Aoife, Panicek, David M, Zabor, Emily C, Moskowitz, Chaya S, Bitar, Richard, Motzer, Robert J, Hricak, Hedvig, Ginsberg, Michelle S

“…To assess variability of computed tomographic (CT) measurements of lesions of various sizes and margin sharpness in several organs taken by readers with…”
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Phase I Trial of Bevacizumab Plus Escalated Doses of Sunitinib in Patients With Metastatic Renal Cell Carcinoma by FELDMAN, Darren R, BAUM, Michael S, MOTZER, Robert J, GINSBERG, Michelle S, HASSOUN, Hani, FLOMBAUM, Carlos D, VELASCO, Susanne, FISCHER, Patricia, RONNEN, Ellen, ISHILL, Nicole, PATIL, Sujata

“…Both bevacizumab and sunitinib target the vascular endothelial growth factor pathway and demonstrate activity against advanced renal cell carcinoma (RCC). In…”
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Variability of Lung Tumor Measurements on Repeat Computed Tomography Scans Taken Within 15 Minutes by OXNARD, Geoffrey R, BINSHENG ZHAO, SIMA, Camelia S, GINSBERG, Michelle S, JAMES, Leonard P, LEFKOWITZ, Robert A, PINGZHEN GUO, KRIS, Mark G, SCHWARTZ, Lawrence H, RIELY, Gregory J

“…We use changes in tumor measurements to assess response and progression, both in routine care and as the primary objective of clinical trials. However, the…”
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EGFR Exon 19 Insertions: A New Family of Sensitizing EGFR Mutations in Lung Adenocarcinoma by MAI HE, CAPELLETTI, Marzia, JÄNNE, Pasi A, LADANYI, Marc, OXNARD, Geoffrey R, NAFA, Khedoudja, YUN, Cai-Hong, ARCILA, Maria E, MILLER, Vincent A, GINSBERG, Michelle S, BINSHENG ZHAO, KRIS, Mark G, ECK, Michael J

“…Epidermal growth factor receptor (EGFR) genotyping is now standard in the management of advanced lung adenocarcinoma, as this biomarker predicts marked benefit…”
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CT Findings of Chemotherapy-induced Toxicity: What Radiologists Need to Know about the Clinical and Radiologic Manifestations of Chemotherapy Toxicity by TORRISI, Jean M, SCHWARTZ, Lawrence H, GOLLUB, Marc J, GINSBERG, Michelle S, BOSL, George J, HRICAK, Hedvig

“…Cancer chemotherapy has evolved from cytotoxic agents and now includes several new agents that target specific molecules responsible for the regulation of cell…”
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Activity of SU11248, a Multitargeted Inhibitor of Vascular Endothelial Growth Factor Receptor and Platelet-Derived Growth Factor Receptor, in Patients With Metastatic Renal Cell Carcinoma by MOTZER, Robert J, MICHAELSON, M. Dror, LI, Jim Z, BELLO, Carlo L, THEUER, Charles P, GEORGE, Daniel J, RINI, Brian I, REDMAN, Bruce G, HUDES, Gary R, WILDING, George, FIGLIN, Robert A, GINSBERG, Michelle S, KIM, Sindy T, BAUM, Charles M, DEPRIMO, Samuel E

“…Renal cell carcinoma (RCC) is characterized by loss of von Hippel Lindau tumor suppressor gene activity, resulting in high expression of pro-angiogenic growth…”
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Risk stratification of cardiac metastases using late gadolinium enhancement cardiovascular magnetic resonance: prognostic impact of hypo-enhancement evidenced tumor avascularity by Chan, Angel T, Dinsfriend, William, Kim, Jiwon, Yum, Brian, Sultana, Razia, Klebanoff, Christopher A, Plodkowski, Andrew, Perez Johnston, Rocio, Ginsberg, Michelle S, Liu, Jennifer, Kim, Raymond J, Steingart, Richard, Weinsaft, Jonathan W

“…Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) is widely used to identify cardiac neoplasms, for which diagnosis is predicated on…”
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A phase II study of obatoclax mesylate, a Bcl-2 antagonist, plus topotecan in relapsed small cell lung cancer by Paik, Paul K, Rudin, Charles M, Pietanza, Maria C, Brown, Andrew, Rizvi, Naiyer A, Takebe, Naoko, Travis, William, James, Leonard, Ginsberg, Michelle S, Juergens, Rosalyn, Markus, Susan, Tyson, Leslie, Subzwari, Sara, Kris, Mark G, Krug, Lee M

“…Abstract Introduction We previously reported data on the safety, tolerability, and recommended phase II dose of obatoclax mesylate in conjunction with…”
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Lung cancer: computerized quantification of tumor response--initial results by Zhao, Binsheng, Schwartz, Lawrence H, Moskowitz, Chaya S, Ginsberg, Michelle S, Rizvi, Naiyer A, Kris, Mark G

“…To prospectively quantify tumor response or progression in patients with lung cancer by using thin-section computed tomography (CT) and a semiautomated…”
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Correlation between tumor measurement on Computed Tomography and resected specimen size in lung adenocarcinomas by Lampen-Sachar, Katharine, Zhao, Binsheng, Zheng, Junting, Moskowitz, Chaya S, Schwartz, Lawrence H, Zakowski, Maureen F, Rizvi, Naiyer A, Kris, Mark G, Ginsberg, Michelle S

“…Abstract Objective To compare preoperative size of stage I and stage II lung adenocarcinoma as measured by Computed Tomography (CT) and as assessed on gross…”
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Prognostic Implications of the Distribution of Lymph Node Metastases in Rectal Cancer After Neoadjuvant Chemoradiotherapy by LEIBOLD, Tobias, SHIA, Jinru, GUILLEM, José G, RUO, Leyo, MINSKY, Bruce D, AKHURST, Timothy, GOLLUB, Marc J, GINSBERG, Michelle S, LARSON, Steven, RIEDEL, Elyn, WONG, W. Douglas

“…After preoperative chemoradiotherapy of rectal cancer, the number of retrievable and metastatic lymph nodes is decreased. The current TNM classification is…”
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Harnessing Technology to Improve Clinical Trials: Study of Real-Time Informatics to Collect Data, Toxicities, Image Response Assessments, and Patient-Reported Outcomes in a Phase II Clinical Trial by PIETANZA, M. Catherine, BASCH, Ethan M, GABOW, Aaron, LATIF, Marcia, LIN, Kai-Hsiung, QINFEI WU, KASS, Samantha L, MILLER, Claire P, TYSON, Leslie, SUMNER, Dyana K, BERKOWITZ-HERGIANTO, Alison, SIMA, Camelia S, LASH, Alex, KRIS, Mark G, SCHWARTZ, Lawrence H, GINSBERG, Michelle S, BINSHENG ZHAO, SHOUERY, Marwan, SHAW, Mary, ROGAK, Lauren J, WILSON, Manda

“…In clinical trials, traditional monitoring methods, paper documentation, and outdated collection systems lead to inaccuracies of study information and…”
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Postoperative complications after thoracic surgery for lung cancer by Rotman, Jessica A, Plodkowski, Andrew J, Hayes, Sara A, de Groot, Patricia M, Shepard, Jo-Anne O, Munden, Reginald F, Ginsberg, Michelle S

“…Abstract Lung cancer is the leading cause of cancer-related deaths in the United States. Several surgical techniques are currently used as part of the standard…”
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phase I study of obatoclax mesylate, a Bcl-2 antagonist, plus topotecan in solid tumor malignancies by Paik, Paul K, Rudin, Charles M, Brown, Andrew, Rizvi, Naiyer A, Takebe, Naoko, Travis, William, James, Leonard, Ginsberg, Michelle S, Juergens, Rosalyn, Markus, Susan, Tyson, Leslie, Subzwari, Sara, Kris, Mark G, Krug, Lee M

“…Purpose To establish the safety, maximum tolerated dose (MTD), recommended phase II dose, and preliminary antitumor activity of obatoclax mesylate…”
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Phase 1 Clinical Trial of Trametinib and Ponatinib in Patients With NSCLC Harboring KRAS Mutations by Arbour, Kathryn C., Manchado, Eusebio, Bott, Matthew J., Ahn, Linda, Tobi, Yosef, Ni, Andy Ai, Yu, Helena A., Shannon, Alyssa, Ladanyi, Marc, Perron, Victoria, Ginsberg, Michelle S., Johnson, Amanda, Holodny, Andrei, Kris, Mark G., Rudin, Charles M., Lito, Piro, Rosen, Neal, Lowe, Scott, Riely, Gregory J.

“…Somatic KRAS mutations occur in 25% of patients with NSCLC. Treatment with MEK inhibitor monotherapy has not been successful in clinical trials to date…”
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Pulmonary toxicity associated with erlotinib by Liu, Vincent, White, Dorothy A, Zakowski, Maureen F, Travis, William, Kris, Mark G, Ginsberg, Michelle S, Miller, Vincent A, Azzoli, Christopher G

“…Interstitial lung disease (ILD) related to therapy with the drug gefitinib has been well reported. The adverse pulmonary effects of erlotinib are less well…”
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Natural History of Patients with Subcentimeter Pulmonary Nodules Undergoing Hepatic Resection for Metastatic Colorectal Cancer by Maithel, Shishir K., MD, Ginsberg, Michelle S., MD, D'Amico, Francesco, MD, DeMatteo, Ronald P., MD, FACS, Allen, Peter J., MD, FACS, Fong, Yuman, MD, FACS, Blumgart, Leslie H., MD, FACS, Jarnagin, William R., MD, FACS, D'Angelica, Michael I., MD

“…Background CT imaging frequently detects subcentimeter pulmonary nodules (SPN) in patients undergoing resection of colorectal cancer liver metastases. Their…”
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Epidemiology of Lung Cancer by McErlean, Aoife, MB, BCH, BAO, Ginsberg, Michelle S., MD

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