Search Results - "Michell, Belinda J."

AMPK-independent pathways regulate skeletal muscle fatty acid oxidation by Dzamko, Nicolas, Schertzer, Jonathan D., Ryall, James G., Steel, Rohan, Macaulay, S. Lance, Wee, Sheena, Chen, Zhi‐Ping, Michell, Belinda J., Oakhill, Jonathan S., Watt, Matthew J., Jørgensen, Sebastian Beck, Lynch, Gordon S., Kemp, Bruce E., Steinberg, Gregory R.

“…The activation of AMP-activated protein kinase (AMPK) and phosphorylation/inhibition of acetyl-CoA carboxylase 2 (ACC2) is believed to be the principal pathway…”
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Structure of the lysine specific protease Kgp from Porphyromonas gingivalis, a target for improved oral health by Gorman, Michael A., Seers, Christine A., Michell, Belinda J., Feil, Susanne C., Huq, N. Laila, Cross, Keith J., Reynolds, Eric C., Parker, Michael W.

“…The oral pathogen Porphyromonas gingivalis is a keystone pathogen in the development of chronic periodontitis. Gingipains, the principle virulence factors of…”
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Phosphorylation regulates copper-responsive trafficking of the Menkes copper transporting P-type ATPase by Veldhuis, Nicholas A., Valova, Valentina A., Gaeth, Ann P., Palstra, Nickless, Hannan, Katherine M., Michell, Belinda J., Kelly, Leonard E., Jennings, Ian, Kemp, Bruce E., Pearson, Richard B., Robinson, Phillip J., Camakaris, James

“…The Menkes copper-translocating P-type ATPase (ATP7A) is a critical copper transport protein functioning in systemic copper absorption and supply of copper to…”
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Identification of Regulatory Sites of Phosphorylation of the Bovine Endothelial Nitric-oxide Synthase at Serine 617 and Serine 635 by Michell, Belinda J, Harris, M Brennan, Chen, Zhi-Ping, Ju, Hong, Venema, Virginia J, Blackstone, Michele A, Huang, Wei, Venema, Richard C, Kemp, Bruce E

“…Endothelial nitric-oxide synthase (eNOS) is regulated by signaling pathways involving multiple sites of phosphorylation. The coordinated phosphorylation of…”
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Effect of exercise on protein kinase C activity and localization in human skeletal muscle by Rose, Adam J., Michell, Belinda J., Kemp, Bruce E., Hargreaves, Mark

“…To investigate the effect of exercise on protein kinase C (PKC) activity and localization in human skeletal muscle, eight healthy men performed cycle ergometer…”
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Crystal structure of human insulin‐regulated aminopeptidase with specificity for cyclic peptides by Hermans, Stefan J., Ascher, David B., Hancock, Nancy C., Holien, Jessica K., Michell, Belinda J., Chai, Siew Yeen, Morton, Craig J., Parker, Michael W.

“…Insulin‐regulated aminopeptidase (IRAP or oxytocinase) is a membrane‐bound zinc‐metallopeptidase that cleaves neuroactive peptides in the brain and produces…”
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Tumor necrosis factor α-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling by Steinberg, Gregory R., Michell, Belinda J., van Denderen, Bryce J.W., Watt, Matthew J., Carey, Andrew L., Fam, Barbara C., Andrikopoulos, Sofianos, Proietto, Joseph, Görgün, Cem Z., Carling, David, Hotamisligil, Gökhan S., Febbraio, Mark A., Kay, Thomas W., Kemp, Bruce E.

“…Elevated levels of tumor necrosis factor (TNFα) are implicated in the development of insulin resistance, but the mechanisms mediating these chronic effects are…”
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AMPK β Subunit Targets Metabolic Stress Sensing to Glycogen by Polekhina, Galina, Gupta, Abhilasha, Michell, Belinda J., van Denderen, Bryce, Murthy, Sid, Feil, Susanne C., Jennings, Ian G., Campbell, Duncan J., Witters, Lee A., Parker, Michael W., Kemp, Bruce E., Stapleton, David

“…AMP-activated protein kinase (AMPK) is a multisubstrate enzyme activated by increases in AMP during metabolic stress caused by exercise, hypoxia, lack of cell…”
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AMP-activated protein kinase isoenzyme family: subunit structure and chromosomal location by Stapleton, David, Woollatt, Erica, Mitchelhill, Ken I, Nicholl, Jillian K, Fernandez, C.Shamala, Michell, Belinda J, Witters, Lee A, Power, David A, Sutherland, Grant R, Kemp, Bruce E

“…The AMP-activated protein kinase (AMPK) consists of catalytic α and non-catalytic, β and γ (38 kDa) subunits and is responsible for acting as a metabolic…”
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Coordinated Control of Endothelial Nitric-oxide Synthase Phosphorylation by Protein Kinase C and the cAMP-dependent Protein Kinase by Michell, Belinda J., Chen, Zhi-ping, Tiganis, Tony, Stapleton, David, Katsis, Frosa, Power, David A., Sim, Alistair T., Kemp, Bruce E.

“…Endothelial nitric-oxide synthase (eNOS) is an important regulatory enzyme in the cardiovascular system catalyzing the production of NO from arginine. Multiple…”
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Shear stress stimulates phosphorylation of eNOS at Ser(635) by a protein kinase A-dependent mechanism by Boo, Yong Chool, Hwang, Jinah, Sykes, Michelle, Michell, Belinda J, Kemp, Bruce E, Lum, Hazel, Jo, Hanjoong

“…Shear stress stimulates nitric oxide (NO) production by phosphorylating endothelial NO synthase (eNOS) at Ser(1179) in a phosphoinositide-3-kinase (PI3K)- and…”
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AMP-activated Protein Kinase β Subunit Tethers α and γ Subunits via Its C-terminal Sequence (186–270) by Iseli, Tristan J., Walter, Mark, van Denderen, Bryce J.W., Katsis, Frosa, Witters, Lee A., Kemp, Bruce E., Michell, Belinda J., Stapleton, David

“…AMP-activated protein kinase (AMPK) is an important metabolic stress-sensing protein kinase responsible for regulating metabolism in response to changing…”
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Reciprocal Phosphorylation and Regulation of Endothelial Nitric-oxide Synthase in Response to Bradykinin Stimulation by Harris, M. Brennan, Ju, Hong, Venema, Virginia J., Liang, Haiying, Zou, Rong, Michell, Belinda J., Chen, Zhi-Ping, Kemp, Bruce E., Venema, Richard C.

“…Endothelial nitric-oxide synthase (eNOS) is phosphorylated at Ser-1179 (bovine sequence) by Akt after growth factor or shear stress stimulation of endothelial…”
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AMP-activated protein kinase phosphorylation of endothelial NO synthase by Chen, Zhi-Ping, Mitchelhill, Ken I, Michell, Belinda J, Stapleton, David, Rodriguez-Crespo, Ignacio, Witters, Lee A, Power, David A, Ortiz de Montellano, Paul R, Kemp, Bruce E

“…The AMP-activated protein kinase (AMPK) in rat skeletal and cardiac muscle is activated by vigorous exercise and ischaemic stress. Under these conditions AMPK…”
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Dealing with energy demand: the AMP-activated protein kinase by Kemp, Bruce E, Mitchelhill, Ken I, Stapleton, David, Michell, Belinda J, Chen, Zhi-Ping, Witters, Lee A

“…The AMP-activated protein kinase (AMPK) is a member of a metabolite-sensing protein kinase family that is found in all eukaryotes. AMPK activity is regulated…”
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AMPK signaling in contracting human skeletal muscle: acetyl-CoA carboxylase and NO synthase phosphorylation by Chen, Z P, McConell, G K, Michell, B J, Snow, R J, Canny, B J, Kemp, B E

“…AMP-activated protein kinase (AMPK) is a metabolic stress-sensing protein kinase responsible for coordinating metabolism and energy demand. In rodents,…”
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Mammalian AMP-activated Protein Kinase Subfamily (∗) by Stapleton, David, Mitchelhill, Ken I., Gao, Guang, Widmer, Jane, Michell, Belinda J., Teh, Trazel, House, Colin M., Fernandez, C. Shamala, Cox, Timothy, Witters, Lee A., Kemp, Bruce E.

“…The mammalian 5′-AMP-activated protein kinase (AMPK) is related to a growing family of protein kinases in yeast and plants that are regulated by nutritional…”
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AMP-activated Protein Kinase Subunit Interactions: β1:γ1 ASSOCIATION REQUIRES β1 Thr-263 AND Tyr-267 by Iseli, Tristan J, Oakhill, Jonathan S, Bailey, Michael F, Wee, Sheena, Walter, Mark, van Denderen, Bryce J, Castelli, Laura A, Katsis, Frosa, Witters, Lee A, Stapleton, David, Macaulay, S. Lance, Michell, Belinda J, Kemp, Bruce E

“…AMP-activated protein kinase (AMPK) plays multiple roles in the body's overall metabolic balance and response to exercise, nutritional stress, hormonal…”
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Differential calcineurin signalling activity and regeneration efficacy in diaphragm and limb muscles of dystrophic mdx mice by Stupka, Nicole, Michell, Belinda J., Kemp, Bruce E., Lynch, Gordon S.

“…Calcineurin activity is essential for successful skeletal muscle regeneration in young mdx mice and in wild type mice following myotoxic injury and cryodamage…”
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Expression of the AMP-activated protein kinase β1 and β2 subunits in skeletal muscle by Chen, Zhi-ping, Heierhorst, Jörg, Mann, Richard J., Mitchelhill, Ken I., Michell, Belinda J., Witters, Lee A., Lynch, Gordon S., Kemp, Bruce E., Stapleton, David

“…A heterotrimeric member of the AMP-activated protein kinase (AMPK) isoenzyme family was purified from rat skeletal muscle by immunoaffinity chromatography,…”
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