Search Results - "Michell, A. W."

Biomarkers and Parkinson's disease by Michell, A. W., Lewis, S. J. G., Foltynie, T., Barker, R. A.

“…Biomarkers are characteristics that can be measured as an indicator of a normal biological process, and they have special relevance in Parkinson's disease…”
Get full text

Saccadic latency distributions in Parkinson's disease and the effects of L-dopa by MICHELL, A. W, XU, Z, FRITZ, D, LEWIS, S. J. G, FOLTYNIE, T, WILLIAMS-GRAY, C. H, ROBBINS, T. W, CARPENTER, R. H. S, BARKER, R. A

“…Parkinson's disease (PD) is associated with a loss of central dopaminergic pathways in the brain leading to an abnormality of movement, including saccades. In…”
Get full text

Transient haemodynamic events in neurologically compromised infants: A simultaneous EEG and diffuse optical imaging study by Cooper, R.J., Hebden, Jeremy C., O'Reilly, H., Mitra, S., Michell, A.W., Everdell, N.L., Gibson, A.P., Austin, T.

“…We describe a series of novel simultaneous EEG and diffuse optical imaging studies of newborn infants. These experiments provide evidence of large, transient…”
Get full text

The use of quantitative oculometry in the assessment of Huntington's disease by ALI, F. R, MICHELL, A. W, BARKER, R. A, CARPENTER, R. H. S

“…Huntington's disease (HD) is a neurodegenerative disorder characterised by progressive motor, cognitive and psychiatric symptoms. Objective measurement of…”
Get full text

The effect of truncated human alpha-synuclein (1-120) on dopaminergic cells in a transgenic mouse model of Parkinson's disease by Michell, A W, Tofaris, G K, Gossage, H, Tyers, P, Spillantini, M G, Barker, R A

“…Alpha-Synuclein is thought to play an important role in the pathology of Parkinson's disease (PD). Truncated forms of this protein can be found in PD brain…”
Get full text

GJB1 gene mutations in suspected inflammatory demyelinating neuropathies not responding to treatment by Michell, A W, Laura, M, Blake, J, Lunn, M P, Cox, A, Gibbons, V S, Davis, M B, Wood, N W, Manji, H, Houlden, H, Murray, N M F, Reilly, M M

“…Other groups have reported isolated cases with GJB1 mutations in whom NCS have shown heterogeneous motor conduction velocities in a single nerve as well as…”
Get full text

Hand tapping: A simple, reproducible, objective marker of motor dysfunction in Huntington’s disease by Michell, A. W., Goodman, A. O. G., Silva, A. H. D., Lazic, S. E., Morton, A. J., Barker, R. A.

“…Huntington’s disease (HD) is a severe neurodegenerative condition in which the impairment in voluntary movement is related to functional disability. Clinical…”
Get full text

Central pontine myelinolysis temporally related to hypophosphataemia by Michell, A W, Burn, D J, Reading, P J

Get full text

Can endogenous stem cells be stimulated to repair the degenerating brain? by Michell, A. W., Phillips, W., Barker, R. A.

Get full text

Isolated motor conduction block associated with infliximab by Michell, A. W., Gaitatzis, A., Burge, J., Reilly, M. M., Kapoor, R., Koltzenburg, M.

Get full text

Isolated cerebellar syndrome following head injury with short posttraumatic amnesia by MICHELL, A. W, BURN, D. J

“…We present the case of a man developing a profound cerebellar syndrome within 24 h of a minor head injury. His neuroimaging was normal and no other cause was…”
Get full text

PATU1 Characteristic faciobrachial dystonic seizures as an immunotherapy-responsive prodrome to voltage-gated potassium channel antibody-associated limbic encephalitis by Irani, S, Michell, A W, Lang, B, Vincent, A, Sommerville, E R, Johnson, M R, Smith, S M J

“…LE defines the subacute onset of amnesia and seizures. However, there are few reliable clinical features distinguishing VGKC-antibody associated LE from the…”
Get full text

A case of late onset sporadic Parkinson’s disease with an A53T mutation in α-synuclein by Michell, A W, Barker, R A, Raha-Chowdhury, R, Raha, S K

Get full text

Ski Boot Neuropathy by Michell, A. W., Hampton, J. L., Turner, N. C.

“…This year’s skiing trip had an unusually neurological flavour, reminding us of what we once knew – the neuroanatomy of the foot. And what we should have known…”
Get full text

Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles by Underwood, Benjamin R., Broadhurst, David, Dunn, Warwick B., Ellis, David I., Michell, Andrew W., Vacher, Coralie, Mosedale, David E., Kell, Douglas B., Barker, Roger A., Grainger, David J., Rubinsztein, David C.

“…There has been considerable progress recently towards developing therapeutic strategies for Huntington's disease (HD), with several compounds showing…”
Get full text

A case of late onset sporadic Parkinson's disease with an A53T mutation in  -synuclein by Michell, A W

“…Genetic analysis PCR primers were designed from 5[variant prime] untranslated region (UTR) and 3[variant prime]UTR spanning each exon of [alpha]-synuclein…”
Get full text

Skin and platelet α-synuclein as peripheral biomarkers of Parkinson's disease by Michell, Andrew W., Luheshi, Leila M., Barker, Roger A.

“…Parkinson's disease (PD) is a heterogeneous disease that can be difficult to diagnose, and for which we have no simple effective biomarker. In this study we…”
Get full text

Lewy bodies in Parkinson's disease: Protectors or perpetrators? by Harrower, Timothy P., Michell, Andrew W., Barker, Roger A.

Get full text

Central pontine myelinolysis temporally related to hypophosphataemia by Michell, A W, Burn, D J, Reading, P J

Get full text

A case of late onset sporadic Parkinson's disease with an A53T mutation in alpha-synuclein by Michell, A W, Barker, R A, Raha, S K, Raha-Chowdhury, R

Get full text