Search Results - "Michele S. Swanson"

Inhibition of host vacuolar H+-ATPase activity by a Legionella pneumophila effector by Xu, Li, Shen, Xihui, Bryan, Andrew, Banga, Simran, Swanson, Michele S, Luo, Zhao-Qing

“…Legionella pneumophila is an intracellular pathogen responsible for Legionnaires' disease. This bacterium uses the Dot/Icm type IV secretion system to inject a…”
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ppGpp Conjures Bacterial Virulence by DALEBROUX, Zachary D, SVENSSON, Sarah L, GAYNOR, Erin C, SWANSON, Michele S

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Assessment of the Legionnaires’ disease outbreak in Flint, Michigan by Zahran, Sammy, McElmurry, Shawn P., Kilgore, Paul E., Mushinski, David, Press, Jack, Love, Nancy G., Sadler, Richard C., Swanson, Michele S.

“…The 2014–2015 Legionnaires’ disease (LD) outbreak in Genesee County, MI, and the outbreak resolution in 2016 coincided with changes in the source of drinking…”
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Symbiont-Mediated Defense against Legionella pneumophila in Amoebae by König, Lena, Wentrup, Cecilia, Schulz, Frederik, Wascher, Florian, Escola, Sarah, Swanson, Michele S, Buchrieser, Carmen, Horn, Matthias

“…is an important opportunistic pathogen for which environmental reservoirs are crucial for the infection of humans. In the environment, free-living amoebae…”
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Autophagy is an immediate macrophage response to Legionella pneumophila by Amer, Amal O., Swanson, Michele S.

“…Summary After ingestion by macrophages, Legionella pneumophila enter spacious vacuoles that are quickly enveloped by endoplasmic reticulum (ER), then slowly…”
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Inflammasome components coordinate autophagy and pyroptosis as macrophage responses to infection by Byrne, Brenda G, Dubuisson, Jean-Francois, Joshi, Amrita D, Persson, Jenny J, Swanson, Michele S

“…When microbes contaminate the macrophage cytoplasm, leukocytes undergo a proinflammatory death that is initiated by nucleotide-binding-domain-,…”
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SpoT governs Legionella pneumophila differentiation in host macrophages by Dalebroux, Zachary D, Edwards, Rachel L, Swanson, Michele S

“…During its life cycle, Legionella pneumophila alternates between a replicative and a transmissive state. To determine their contributions to L. pneumophila…”
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Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection by Molofsky, Ari B, Byrne, Brenda G, Whitfield, Natalie N, Madigan, Cressida A, Fuse, Etsu T, Tateda, Kazuhiro, Swanson, Michele S

“…To restrict infection by Legionella pneumophila, mouse macrophages require Naip5, a member of the nucleotide-binding oligomerization domain leucine-rich repeat…”
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Autophagy: Eating for Good Health by Swanson, Michele S

“…A renaissance in the autophagy field has illuminated many areas of biology, and infectious disease is no exception. By identifying key components of this…”
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Differentiate to thrive: lessons from the Legionella pneumophila life cycle by Molofsky, Ari B., Swanson, Michele S.

“…Summary When confronted by disparate environments, microbes routinely alter their physiology to tolerate or exploit local conditions. But some circumstances…”
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Listeriolysin O is necessary and sufficient to induce autophagy during Listeria monocytogenes infection by Meyer-Morse, Nicole, Robbins, Jennifer R, Rae, Chris S, Mochegova, Sofia N, Swanson, Michele S, Zhao, Zijiang, Virgin, Herbert W, Portnoy, Daniel

“…Recent studies have suggested that autophagy is utilized by cells as a protective mechanism against Listeria monocytogenes infection. However we find autophagy…”
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Distinct roles of ppGpp and DksA in Legionella pneumophila differentiation by Dalebroux, Zachary D, Yagi, Brian F, Sahr, Tobias, Buchrieser, Carmen, Swanson, Michele S

“…To transit between hosts, intracellular Legionella pneumophila transform into a motile, infectious, transmissive state. Here we exploit the pathogen's life…”
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Secrets of a successful pathogen: legionella resistance to progression along the autophagic pathway by Joshi, Amrita D, Swanson, Michele S

“…To proliferate within phagocytes, Legionella pneumophila relies on Type IV secretion to modulate host cellular pathways. Autophagy is an evolutionarily…”
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Legionella pneumophila couples fatty acid flux to microbial differentiation and virulence by Edwards, Rachel L, Dalebroux, Zachary D, Swanson, Michele S

“…During its life cycle, Legionella pneumophila alternates between at least two phenotypes: a resilient, infectious form equipped for transmission and a…”
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Membrane Vesicles Shed by Legionella pneumophila Inhibit Fusion of Phagosomes with Lysosomes by Fernandez-Moreira, Esteban, Helbig, Juergen H, Swanson, Michele S

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The phtC-phtD Locus Equips Legionella pneumophila for Thymidine Salvage and Replication in Macrophages by Fonseca, Maris V, Sauer, John-Demian, Crepin, Sebastien, Byrne, Brenda, Swanson, Michele S

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Efficient Generation of Unmarked Deletions in Legionella pneumophila by BRYAN, Andrew, HARADA, Kaoru, SWANSON, Michele S

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Legionella pneumophila CsrA is a pivotal repressor of transmission traits and activator of replication by Molofsky, Ari B., Swanson, Michele S.

“…Summary Legionella pneumophila can replicate inside amoebae and also alveolar macrophages to cause Legionnaires’ Disease in susceptible hosts. When nutrients…”
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ppGpp: magic beyond RNA polymerase by Dalebroux, Zachary D., Swanson, Michele S.

“…Key Points To tolerate stress, many bacteria rely on the signalling nucleotides guanosine tetraphosphate and guanosine pentaphosphate (collectively referred to…”
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Nicotinic Acid Modulates Legionella pneumophila Gene Expression and Induces Virulence Traits by Edwards, Rachel L, Bryan, Andrew, Jules, Matthieu, Harada, Kaoru, Buchrieser, Carmen, Swanson, Michele S

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