Search Results - "Michel Mualém de Moraes Alves"

Assessment of In Vitro Anti-melanoma Potential of Ephedranthus pisocarpus R.E.Fr by SANTOS, LUBNA KARINE BESERRA, VERAS, MÁRCIA DENISE ALVES, MARQUES, KARINNE KELLY GADELHA, DE MORAES ALVES, MICHEL MUALÉM, MENDES, ANDERSON NOGUEIRA, DE AMORIM CARVALHO, FERNANDO AÉCIO, SOBRAL, MARIANNA VIEIRA, CHAVES, MARIANA HELENA, GONÇALVES, JUAN CARLOS RAMOS

“…Background/Aim: Despite being a rare disease, melanoma is considered the most dangerous skin cancer due to its highly invasive and aggressive nature, and still…”
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Biflavones from Platonia insignis Mart. Flowers Promote In Vitro Antileishmanial and Immunomodulatory Effects against Internalized Amastigote Forms of Leishmania amazonensis by Bezerra, Érika Alves, Alves, Michel Mualém de Moraes, Lima, Simone Kelly Rodrigues, Pinheiro, Emanuelly Elanny Andrade, Amorim, Layane Valéria, Lima Neto, José de Sousa, Carvalho, Fernando Aécio de Amorim, Citó, Antônia Maria das Graças Lopes, Arcanjo, Daniel Dias Rufino

“…Leishmaniasis is an infectious disease that affects millions of people worldwide, making the search essential for more accessible treatments. The species Mart…”
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Platonia insignis Mart., a Brazilian Amazonian Plant: The Stem Barks Extract and Its Main Constituent Lupeol Exert Antileishmanial Effects Involving Macrophages Activation by Arcanjo, Daniel Dias Rufino, Carvalho, Fernando Aécio de Amorim, Chaves, Mariana H., Freitas, Sâmya Danielle Lima, Costa, Isabella Cristhina Gonçalves, Sobrinho-Júnior, Enoque Pereira Costa, Oliveira, Luciano Gomes De Castro, Brito, Lucas Moreira, Alves, Michel Muálem de Moraes, Souza, Adriana Cunha, Rodrigues, Klinger Antonio da Franca

“…Platonia insignis Mart., popularly known as “bacurizeiro,” is used in traditional medical practices based on its diverse biological properties. This study was…”
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Gallic and Ellagic Acids Are Promising Adjuvants to Conventional Amphotericin B for the Treatment of Cutaneous Leishmaniasis by Alves, Michel Muálem de Moraes, Arcanjo, Daniel Dias Rufino, Figueiredo, Kayo Alves, Oliveira, Jéssica Sara de Sousa Macêdo, Viana, Felipe José Costa, Coelho, Elvilene de Sousa, Lopes, Glaucia Lais Nunes, Gonçalves, Juan Carlos Ramos, Carvalho, André Luís Menezes, Rizzo, Márcia Dos Santos, Chaves, Mariana Helena, Mendonça, Ivete Lopes de, Carvalho, Fernando Aécio de Amorim

“…In this study, we demonstrated the potential associative effect of combining conventional amphotericin B (Amph B) with gallic acid (GA) and with ellagic acid…”
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Gallic and ellagic acids: two natural immunomodulator compounds solve infection of macrophages by Leishmania major by Alves, Michel Muálem de Moraes, Brito, Lucas Moreira, Souza, Adriana Cunha, Queiroz, Bárbara Cristina Silva Holanda, de Carvalho, Thaynara Parente, Batista, Joilson Ferreira, Oliveira, Jéssica Sara de Sousa Macêdo, de Mendonça, Ivete Lopes, Lira, Silvéria Regina de Sousa, Chaves, Mariana Helena, Gonçalves, Juan Carlos Ramos, Carneiro, Sabrina Maria Portela, Arcanjo, Daniel Dias Rufino, Carvalho, Fernando Aécio de Amorim

“…Leishmaniasis is a complex of parasitic protozoan diseases caused by more than 20 different species of parasites from Leishmania genus. Conventional treatments…”
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In vitro bioactivity and cytotoxicity of films based on mesocarp of Orbignya sp. and carboxymethylcellulose as a tannic acid release matrix by de Sousa Leal, Antonia, de Araújo, Ricardo, Rocha Souza, Grasielly, Nunes Lopes, Gláucia Laís, Telles Pereira, Sean, Muálem de Moraes Alves, Michel, Medeiros Barreto, Humberto, Menezes Carvalho, André Luís, Pinheiro Ferreira, Paulo Michel, Silva, Davi, de Amorim Carvalho, Fernando Aécio, Dantas Lopes, José Arimateia, Cunha Nunes, Lívio César

“…•Films based on mesocarp of Orbignya sp. (MB) and carboxymethylcellulose (CMC).•Bioactive films incorporating tannic acid (TA) into the polymer matrix.•The…”
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Novel Scaffold Based on Chitosan Hydrogels/Phthalated Cashew Gum for Supporting Human Dental Pulp Stem Cells by Leite, Yulla Klinger de Carvalho, Oliveira, Antônia Carla de Jesus, Quelemes, Patrick Veras, Neto, Napoleão Martins Argolo, Carvalho, Camila Ernanda Sousa de, Soares Rodrigues, Huanna Waleska, Alves, Michel Muálem de Moraes, Carvalho, Fernando Aécio de Amorim, Arcanjo, Daniel Dias Rufino, Silva-Filho, Edson Cavalcanti da, Durazzo, Alessandra, Lucarini, Massimo, Carvalho, Maria Acelina Martins de, Silva, Durcilene Alves da, Leite, José Roberto de Souza de Almeida

“…Hydrogels are structures that have value for application in the area of tissue engineering because they mimic the extracellular matrix. Naturally obtained…”
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Effect of fortification of extender with α‐terpineol and rosemary essential oil on post‐thaw ovine semsen quality by Bezerra, Ingrid de Morais Araujo, Souza, José Adalmir Torres, Sousa Júnior, Antonio de, Alves, Michel Muálem de Moraes, Nascimento, Isolda Márcia Rocha do, Lustosa, Anselmo Alves, Castelo Branco, Yndyra Nayan Teixeira Carvalho, Sousa, Leonardo da Rocha, Arcanjo, Daniel Dias Rufino, Costa, Amilton Paulo Raposo

“…The goal of the present study was to assess the viability of the cryopreserved ovine (Ovis aries) semen, upon supplementation with α‐terpineol and rosemary…”
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Microgramma vacciniifolia Frond Lectin: In Vitro Anti-leishmanial Activity and Immunomodulatory Effects Against Internalized Amastigote Forms of Leishmania amazonensis by de Souza Aguiar, Lethícia Maria, de Moraes Alves, Michel Muálem, Sobrinho Júnior, Enoque Pereira Costa, Paiva, Patrícia Maria Guedes, de Amorim Carvalho, Fernando Aécio, de Albuquerque, Lidiane Pereira, de Siqueira Patriota, Leydianne Leite, Napoleão, Thiago Henrique

“…Purpose The treatment of leishmaniasis, an anthropozoonosis caused by Leishmania protozoa, is limited by factors, such as adverse effects, toxicity, and…”
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Clinical, hematological, biochemical, and histopathological evaluations in domestic cats (Felis catus) infected by Leishmania infantum by Batista, Joilson Ferreira, Magalhães Neto, Francisco das Chagas Ribeiro, Lopes, Kayo Sandro Pimentel do Prado, Sousa, Carla Menezes Guimarães, Alcântara, Diana Sousa, Baêta, Sílvia de Araújo França, Alves, Michel Muálem de Moraes, Mendonça, Ivete Lopes de

“…A high frequency of feline leishmaniasis has been reported in several countries. However, much information about disease progression in cats still needs to be…”
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Isopropyl Gallate, a Gallic Acid Derivative: In Silico and In Vitro Investigation of Its Effects on Leishmania major by Melo, Danielly Silva de, Nery Neto, José Arimatéa de Oliveira, Santos, Maisa de Sousa Dos, Pimentel, Vinícius Duarte, Carvalho, Rita de Cássia Viana, Sousa, Valéria Carlos de, Sousa, Ruy Gabriel Costa, Nascimento, Lázaro Gomes do, Alves, Michel Muálem de Moraes, Arcanjo, Daniel Dias Rufino, Sousa, Damião Pergentino de, Carvalho, Fernando Aécio de Amorim

“…Isopropyl gallate (IPG) is a polyphenol obtained from alterations in the gallic acid molecule via acid catalysis with previously reported leishmanicidal and…”
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Influence of Plant Age on Chemical Composition, Antimicrobial Activity and Cytotoxicity of Varronia curassavica Jacq. Essential Oil Produced on an Industrial Scale by Farias, Jéssica Pires, Barros, Ana Luisa Alves Nogueira, de Araújo-Nobre, Alyne Rodrigues, Sobrinho-Júnior, Enoque Pereira Costa, Alves, Michel Muálem de Moraes, Carvalho, Fernando Aécio de Amorim, da Franca Rodrigues, Klinger Antonio, de Andrade, Ivanilza Moreira, Silva-Filho, Francisco Artur e, Moreira, Daniel Carneiro, Lima, David Fernandes, Lucarini, Massimo, Durazzo, Alessandra, Arcanjo, Daniel Dias Rufino, de Souza de Almeida Leite, José Roberto

“…Considering the therapeutic potential of Varronia curassavica Jacq. essential oil and the great value in the pharmaceutical market, this study aims to evaluate…”
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Behavior and biocompatibility of rabbit bone marrow mesenchymal stem cells with bacterial cellulose membrane by Silva, Marcello de Alencar, Leite, Yulla Klinger de Carvalho, de Carvalho, Camila Ernanda Sousa, Feitosa, Matheus Levi Tajra, Alves, Michel Muálem de Moraes, Carvalho, Fernando Aécio de Amorim, Neto, Bartolomeu Cruz Viana, Miglino, Maria Angélica, Jozala, Angela Faustino, de Carvalho, Maria Acelina Martins

“…Tissue engineering has been shown to exhibit great potential for the creation of biomaterials capable of developing into functional tissues. Cellular expansion…”
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Methods of macrophages activation and their modulation for the prospection of new antileishmania drugs: a review by Muálem de Moraes Alves, Michel, Arcanjo, Daniel Dias Rufino, Carvalho, Rita Cássia Viana de, Amorim, Layane Valéria, Santos, Ingredy Lopes dos, Santos, Rodolfo Ritchelle Lopes, Figueiredo, Kayo Alves, Figueiredo, Jessica Freire Silva, Sobrinho-Júnior, Enoque Pereira Costa, Cruz, Lucas Pereira Lima da, Sousa, Valeria Carlos, Dos Santos, Laiz Pinheiro, Gonçalves, Juan Carlos Ramos, Carneiro, Sabrina Maria Portela, Ivete Lopes de Mendonça, Fernando Aécio de Amorim Carvalho

“…Leishmaniasis are a group of parasitic zoonoses provoked by protozoa from Leishmania genus and belonging to the group of neglected tropical diseases. The…”
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Evaluation of the serum biochemistry and histopathology of kidney and bladder of dogs with Leishmania sp. in their urine by Batista, Joilson Ferreira, Verçosa, Barbara Laurice Araújo, Alves, Michel Muálem de Moraes, Rocha, Fernanda Samara Barbosa, Carvalho, Rayssa Maria de Araújo, Prianti, Maria das Graças, Queiroz, Bárbara Cristina Silva Holanda, Costa, Carlos Henrique Nery, Mendonça, Ivete Lopes de

“…The visceral establishment of Leishmania infantum in dogs may result in kidney and bladder tissue injury, with L. infantum ending up in urine. This study…”
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Dioclea violacea lectin has potent in vitro leishmanicidal activity against Leishmania infantum via carbohydrate recognition domain by Barbosa, Flávia Eduarda Vidal, de Lima, Dimas Batista, dos Santos, Ana Lúcia Estevam, de Sousa, Valéria Carlos, de Cássia Viana Carvalho, Rita, de Moraes Alves, Michel Mualém, de Lima, Marcos Antônio Pereira, da Silva Souza, Racquel Oliveira, da Silva, Cláudio Gleidiston Lima, Teixeira, Claudener Souza

“…Despite promising advancements in leishmaniasis treatment, existing therapies often face limitations and significant side effects, stimulating the search for…”
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Antileishmanial activity of 2-amino-thiophene derivative SB-200 by Sousa, João Paulo Araujo de, Sousa, Julyanne Maria Saraiva de, Rodrigues, Raiza Raianne Luz, Nunes, Thais Amanda de Lima, Machado, Yasmim Alves Aires, Araujo, Alexandre Carvalho de, da Silva, Ingrid Gracielle Martins, Barros-Cordeiro, Karine Brenda, Báo, Sônia Nair, Alves, Michel Muálem de Moraes, Mendonça-Junior, Francisco Jaime Bezerra, Rodrigues, Klinger Antonio da Franca

“…Leishmaniasis, presenting the highest number of cases worldwide is one of the most serious Neglected Tropical Diseases (NTDs). Clinical manifestations are…”
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In vitro antileishmanial and immunomodulatory activities of the synthetic analogue riparin E by Costa, Luciana Muratori, Muálem de Moraes Alves, Michel, Brito, Lucas Moreira, de Araujo Abi-chacra, Erika, Barbosa-Filho, José Maria, Chavez Gutierrez, Stanley Juan, Barreto, Humberto Medeiros, Aécio de Amorim Carvalho, Fernando

“…Leishmaniases are infectious diseases caused by protozoa of the genus Leishmania, that may have different clinical manifestations. First line drugs used in the…”
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Antileishmanial activity of Riparin structural analogs of Aniba riparia: Biological evaluation, in silico Adme-Tox, and molecular docking by Figueiredo, Kayo Alves, Magalhães Costa, Rayla Kelly, Rocha, Jefferson Almeida, Chavez Gutierrez, Stanley Juan, Ramos, Ricardo Martins, Muálem de Moraes Alves, Michel, Aécio de Amorim Carvalho, Fernando, Menezes Carvalho, André Luis, Lima, Francisco das Chagas Alves

“…We performed a biological evaluation of antileishmanial activity, in silico ADME-Tox profile, and molecular docking of riparins A-F. The antileishmanial…”
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Synthetic hydrazones: In silico studies and in vitro evaluation of the antileishmania potential by de Sousa, Valéria Carlos, de Cássia Viana Carvalho, Rita, dos Reis Barcelar, Karla Germana, de Melo, Danielly Silva, Nunes, Jamylle Melo, de Araújo Sousa, Paulo Sérgio, Rocha, Jefferson Almeida, Lima, Cristiane Costa, de Assis Gonsalves, Arlan, Araújo, Cleônia Roberta Melo, da Costa, Marcília Pinheiro, da Franca Rodrigues, Klinger Antônio, de Moraes Alves, Michel Muálem, de Amorim Carvalho, Fernando Aécio

“…Bioprospecting and synthesis of strategically designed molecules have been used in the search for drugs that can be in leishmaniasis. Hydrazones (HDZ) are…”
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