Search Results - "Michel, Sarah L. J."

Structural Metal Sites in Nonclassical Zinc Finger Proteins Involved in Transcriptional and Translational Regulation by Lee, Seung Jae, Michel, Sarah L. J

“…Conspectus Zinc finger (ZF) proteins are a large family of metalloproteins that utilize zinc for structural purposes. Zinc coordinates to a combination of…”
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Metal-induced oxidative stress and human plasma protein oxidation after SARS-CoV-2 infection by Aryal, Baikuntha, Tillotson, Joseph, Ok, Kiwon, Stoltzfus, Andrew T., Michel, Sarah L. J., Rao, V. Ashutosh

“…Pathogenesis of COVID-19 by SARS-CoV-2 resulted in a global pandemic and public health emergency in 2020. Viral infection can induce oxidative stress through…”
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Cu(I) Disrupts the Structure and Function of the Nonclassical Zinc Finger Protein Tristetraprolin (TTP) by Shimberg, Geoffrey D, Ok, Kiwon, Neu, Heather M, Splan, Kathryn E, Michel, Sarah L. J

“…Tristetraprolin (TTP) is a nonclassical zinc finger (ZF) protein that plays a key role in regulating inflammatory response. TTP regulates cytokines at the mRNA…”
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Cell-Based Therapy in TBI: Magnetic Retention of Neural Stem Cells In Vivo by Shen, Wei-Bin, Plachez, Céline, Tsymbalyuk, Orest, Tsymbalyuk, Natalya, Xu, Su, Smith, Aaron M, Michel, Sarah L J, Yarnell, Deborah, Mullins, Roger, Gullapalli, Rao P, Puche, Adam, Simard, J Marc, Fishman, Paul S, Yarowsky, Paul

“…Stem cell therapy is under active investigation for traumatic brain injury (TBI). Noninvasive stem cell delivery is the preferred method, but retention of stem…”
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Ni(II) coordination to mixed sites modulates DNA binding of HpNikR via a long-range effect by West, Abby L, Evans, Sarah E, González, Javier M, Carter, Lester G, Tsuruta, Hiro, Pozharski, Edwin, Michel, Sarah L. J

“…Helicobacter pylori NikR (HpNikR) is a nickel-dependent transcription factor that regulates multiple genes in the H. pylori pathogen. There are conflicting…”
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Cleavage and polyadenylation specificity factor 30: An RNA-binding zinc-finger protein with an unexpected 2Fe–2S cluster by Shimberg, Geoffrey D., Michalek, Jamie L., Oluyadi, Abdulafeez A., Rodrigues, Andria V., Zucconi, Beth E., Neu, Heather M., Ghosh, Shanchari, Sureschandra, Kanisha, Wilson, Gerald M., Stemmler, Timothy L., Michel, Sarah L. J.

“…Cleavage and polyadenylation specificity factor 30 (CPSF30) is a key protein involved in pre-mRNA processing. CPSF30 contains five Cys₃His domains (annotated…”
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Neural Zinc Finger Factor/Myelin Transcription Factor Proteins: Metal Binding, Fold, and Function by Besold, Angelique N, Michel, Sarah L. J

“…Zinc finger (ZF) proteins make up a large family of metalloproteins that contain discrete domains with amino acid ligands (cysteine and histidine) that serve…”
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Revisiting and re-engineering the classical zinc finger peptide: consensus peptide-1 (CP-1) by Besold, Angelique N, Widger, Leland R, Namuswe, Frances, Michalek, Jamie L, Michel, Sarah L J, Goldberg, David P

“…Zinc plays key structural and catalytic roles in biology. Structural zinc sites are often referred to as zinc finger (ZF) sites, and the classical ZF contains…”
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A single nucleotide change affects fur-dependent regulation of sodB in H. pylori by Carpenter, Beth M, Gancz, Hanan, Gonzalez-Nieves, Reyda P, West, Abby L, Whitmire, Jeannette M, Michel, Sarah L J, Merrell, D Scott

“…Helicobacter pylori is a significant human pathogen that has adapted to survive the many stresses found within the gastric environment. Superoxide Dismutase…”
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Regulation of Copper Toxicity by Candida albicans GPA2 by Schwartz, Jennifer A, Olarte, Karen T, Michalek, Jamie L, Jandu, Gurjinder S, Michel, Sarah L J, Bruno, Vincent M

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Mutagenesis of Conserved Amino Acids of Helicobacter pylori Fur Reveals Residues Important for Function by CARPENTER, Beth M, GANCZ, Hanan, BENOIT, Stéphane L, EVANS, Sarah, OLSEN, Cara H, MICHEL, Sarah L. J, MAIER, Robert J, MERRELL, D. Scott

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cadmium Exchange with Zinc in the Non-Classical Zinc Finger Protein Tristetraprolin by Brandis, Joel E. P, Zalesak, Stephanie M, Kane, Maureen A, Michel, Sarah L. J

“…Tristetraprolin (TTP) is a nonclassical CCCH zinc finger protein that regulates inflammation. TTP targets AU-rich RNA sequences of cytokine mRNAs forming a…”
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Unraveling the RNA Binding Properties of the Iron–Sulfur Zinc Finger Protein CPSF30 by Pritts, Jordan D, Hursey, Matthew S, Michalek, Jamie L, Batelu, Sharon, Stemmler, Timothy L, Michel, Sarah L. J

“…Cleavage and polyadenylation specificity factor 30 (CPSF30) is a “zinc finger” protein that plays a crucial role in the transition of pre-mRNA to RNA. CPSF30…”
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Pb(II) coordination to the nonclassical zinc finger tristetraprolin: retained function with an altered fold by Stoltzfus, Andrew T., Campbell, Courtney J., Worth, Madison M., Hom, Kellie, Stemmler, Timothy L., Michel, Sarah L. J.

“…Tristetraprolin (TTP) is a nonclassical CCCH zinc finger (ZF) that plays a crucial role in regulating inflammation. TTP regulates cytokine mRNAs by specific…”
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Functional characterization of iron-substituted neural zinc finger factor 1: metal and DNA binding by Besold, Angelique N, Lee, Seung Jae, Michel, Sarah L. J, Lue Sue, Niall, Cymet, Holly J

“…Neural zinc finger factor 1 (NZF-1) is a nonclassical zinc finger protein involved in neuronal development. NZF-1 contains multiple copies of a unique CCHHC…”
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Seeing the “Unseeable,” A Student-Led Activity to Identify Metals in Drinking Water by Neu, Heather M, Lee, Merton, Pritts, Jordan D, Sherman, Angela R, Michel, Sarah L. J

“…Municipal drinking water, regulated by the Environmental Protection Agency via the Safe Drinking Water act, has long been assumed to be contaminant-free…”
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Role of Gold in Inflammation and Tristetraprolin Activity by Ok, Kiwon, Li, Wenjing, Neu, Heather M., Batelu, Sharon, Stemmler, Timothy L., Kane, Maureen A., Michel, Sarah L. J.

“…The zinc finger protein tristetraprolin (TTP) regulates inflammation by downregulating cytokine mRNAs. Misregulation results in arthritis, sepsis and cancer,…”
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Functional Characterization of Iron-Substituted Tristetraprolin-2D (TTP-2D, NUP475-2D):  RNA Binding Affinity and Selectivity by diTargiani, Robert C, Lee, Seung Jae, Wassink, Sarah, Michel, Sarah L. J

“…The protein tristetraprolin (TTP, also known as NUP475 and TIS11) is a nonclassical zinc finger protein that is involved in regulating the inflammatory…”
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Understanding RNA Binding by the Nonclassical Zinc Finger Protein CPSF30, a Key Factor in Polyadenylation during Pre-mRNA Processing by Pritts, Jordan D, Oluyadi, Abdulafeez A, Huang, Weiliang, Shimberg, Geoffrey D, Kane, Maureen A, Wilks, Angela, Michel, Sarah L. J

“…Cleavage and polyadenylation specificity factor 30 (CPSF30) is a zinc finger protein that regulates pre-mRNA processing. CPSF30 contains five CCCH domains and…”
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Mining proteomes for zinc finger persulfidation by Li, Haoju, Stoltzfus, Andrew T, Michel, Sarah L. J

“…Hydrogen sulfide (H 2 S) is an endogenous gasotransmitter that signals via persulfidation. There is evidence that the cysteine residues of certain zinc finger…”
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