Search Results - "Michel, R"

Genes and molecular pathways underpinning ciliopathies by Reiter, Jeremy F., Leroux, Michel R.

“…Key Points There are two types of cilia, motile and non-motile primary, which have different roles in human physiology, cell signalling and development…”
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Diastereoselective Ni-Catalyzed Negishi Cross-Coupling Approach to Saturated, Fully Oxygenated C-Alkyl and C-Aryl Glycosides by Gong, Hegui, Gagné, Michel R

“…A Ni-catalyzed Negishi cross-coupling approach to C-glycosides is described with an emphasis on C-aryl glycosides. The combination of NiCl2/PyBox in…”
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Dinuclear Gold−Silver Resting States May Explain Silver Effects in Gold(I)-Catalysis by Weber, Dieter, Gagné, Michel R

“…The resting state of the gold(I)-catalyzed hydroarylation of 1 changes in the presence of Ag+, with silver free catalysts resting at the dinuclear gold…”
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A Photoflow Reactor for the Continuous Photoredox-Mediated Synthesis of C-Glycoamino Acids and C-Glycolipids by Andrews, R. Stephen, Becker, Jennifer J., Gagné, Michel R.

“…Go with the flow: A simple flow reactor has been developed to accommodate highly absorbing [RuL3]2+ photosensitizers for light‐starved photoredox reactions…”
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Mechanistic Analysis of Gold(I)-Catalyzed Intramolecular Allene Hydroalkoxylation Reveals an Off-Cycle Bis(gold) Vinyl Species and Reversible C–O Bond Formation by Brown, Timothy J, Weber, Dieter, Gagné, Michel R, Widenhoefer, Ross A

“…Mechanistic investigation of gold(I)-catalyzed intramolecular allene hydroalkoxylation established a mechanism involving rapid and reversible C–O bond…”
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The roles of evolutionarily conserved functional modules in cilia-related trafficking by Sung, Ching-Hwa, Leroux, Michel R.

“…Cilia are present across most eukaryotic phyla and have diverse sensory and motility functions. Sung and Leroux review the trafficking pathways that modulate…”
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Composition, organization and mechanisms of the transition zone, a gate for the cilium by Park, Kwangjin, Leroux, Michel R

“…The cilium evolved to provide the ancestral eukaryote with the ability to move and sense its environment. Acquiring these functions required the…”
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Shared and Distinct Mechanisms of Compartmentalized and Cytosolic Ciliogenesis by Avidor-Reiss, Tomer, Leroux, Michel R.

“…Most motile and all non-motile (also known as primary) eukaryotic cilia possess microtubule-based axonemes that are assembled at the cell surface to form…”
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Overview of Bacterial Protein Toxins from Pathogenic Bacteria: Mode of Action and Insights into Evolution by Popoff, Michel R

“…Bacterial protein toxins are secreted by certain bacteria and are responsible for mild to severe diseases in humans and animals. They are among the most potent…”
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Gold-Catalyzed Enantioselective Ring-Expanding Cycloisomerization of Cyclopropylidene Bearing 1,5-Enynes by Zheng, Hongchao, Felix, Ryan J, Gagné, Michel R

“…An enantioselective ring-expanding cycloisomerization of 1,5-enynes bearing a cyclopropylidene moiety has been developed. This methodology provides a new…”
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Mechanistic Surprises in the Gold(I)-Catalyzed Intramolecular Hydroarylation of Allenes by Weber, Dieter, Tarselli, Michael A, Gagné, Michel R

“…Two for the show: Mechanistic studies on the cyclization of allenic arenes indicated that the catalyst rests at a dinuclear bridging vinyl structure, which was…”
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Tetanus in animals by Popoff, Michel R.

“…Tetanus is a neurologic disease of humans and animals characterized by spastic paralysis. Tetanus is caused by tetanus toxin (TeNT) produced by Clostridium…”
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Epsilon toxin: a fascinating pore‐forming toxin by Popoff, Michel R.

“…Epsilon toxin (ETX) is produced by strains of Clostridium perfringens classified as type B or type D. ETX belongs to the heptameric β‐pore‐forming toxins…”
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Diastereoselective Pt Catalyzed Cycloisomerization of Polyenes to Polycycles by Geier, Michael J, Gagné, Michel R

“…Application of a tridentate NHC containing pincer ligand to Pt catalyzed cascade cyclization reactions has allowed for the catalytic, diastereoselective…”
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Intermolecular Addition of Glycosyl Halides to Alkenes Mediated by Visible Light by Andrews, R. Stephen, Becker, Jennifer J, Gagné, Michel R

“…Catching photons: Visible light, an amine reductant, and a [Ru(bpy)3]2+ photocatalyst can be used to mediate the addition of glycosyl halides into alkenes to…”
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Safely restarting renal transplant programs should be a priority by Fantus, Daniel, Pâquet, Michel R

“…Many transplant centers have temporarily shut down their living donor kidney transplant programs "to ease pressure on hospitals and protect donors and…”
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Probing the Source of Enhanced Activity in Multiborylated Silsesquioxane Catalysts for C–O Bond Reduction by Starr, Hannah E., Gagné, Michel R.

“…A family of variably borylated silsesquioxanes can be conveniently synthesized by the hydroboration of vinyl- and allyl-modified silsesquioxanes using Piers’…”
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Metal-Free Deoxygenation of Carbohydrates by Adduci, Laura L., McLaughlin, Matthew P., Bender, Trandon A., Becker, Jennifer J., Gagné, Michel R.

“…The conversion of readily available cellulosic biomass to valuable feedstocks and fuels is an attrative goal but a challenging transformation that requires the…”
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Homogeneous catalysis for the production of low-volume, high-value chemicals from biomass by Bender, Trandon A., Dabrowski, Jennifer A., Gagné, Michel R.

“…The transition from petroleum to biorenewable sources of carbon to meet our energy and chemical feedstock needs is difficult, in part because these sources are…”
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Borane- and Silylium-Catalyzed Difunctionalization of Carbohydrates: 3,6-Anhydrosugar Enabled 1,6-Site Selectivity by Clarke, Joshua J., Basemann, Kevin, Romano, Neyen, Lee, Stephen J., Gagné, Michel R.

“…A novel diastereoselective, Lewis acid catalyzed 1,6-difunctionalization of galactose and mannose derivatives has been developed in one pot, via sequential…”
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