Search Results - "Michel, M R"

Clinical Pharmacokinetics and Pharmacodynamics of Propofol by Sahinovic, Marko M., Struys, Michel M. R. F., Absalom, Anthony R.

“…Propofol is an intravenous hypnotic drug that is used for induction and maintenance of sedation and general anaesthesia. It exerts its effects through…”
Get full text

Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine by Weerink, Maud A. S., Struys, Michel M. R. F., Hannivoort, Laura N., Barends, Clemens R. M., Absalom, Anthony R., Colin, Pieter

“…Dexmedetomidine is an α 2 -adrenoceptor agonist with sedative, anxiolytic, sympatholytic, and analgesic-sparing effects, and minimal depression of respiratory…”
Get full text

Correction: Brain changes due to hypoxia during light anaesthesia can be prevented by deepening anaesthesia; a study in rats by Tasbihgou, Setayesh R, Netkova, Mina, Kalmar, Alain F, Doorduin, Janine, Struys, Michel M R F, Schoemaker, Regien G, Absalom, Anthony R

“…[This corrects the article DOI: 10.1371/journal.pone.0193062.]…”
Get full text

Efficiency of CONTRAfluran™ in reducing sevoflurane pollution from maintenance anaesthesia in minimal flow end-tidal control mode for laparoscopic surgery by Mulier, Harold, Struys, Michel M R F, Vereecke, Hugo, Rex, Steffen, Teunkens, An, Kalmar, Alain F

“…Recommendations exist that aim to mitigate the substantial ecological impact of anaesthesia. One option is to use anaesthetic gas capturing technology at…”
Get full text

Ischemia and Reperfusion Injury in Kidney Transplantation: Relevant Mechanisms in Injury and Repair by Nieuwenhuijs-Moeke, Gertrude J, Pischke, Søren E, Berger, Stefan P, Sanders, Jan Stephan F, Pol, Robert A, Struys, Michel M R F, Ploeg, Rutger J, Leuvenink, Henri G D

“…Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms…”
Get full text

Oxygen Reserve Index: Validation of a New Variable by Vos, Jaap Jan, Willems, Cornelis H., van Amsterdam, Kai, van den Berg, Johannes P., Spanjersberg, Rob, Struys, Michel M. R. F., Scheeren, Thomas W. L.

“…BACKGROUND:Pulse oximetry–derived oxygen saturation is typically >97% in normoxia and hyperoxia, limiting its clinical use. The new Oxygen Reserve Index (ORi),…”
Get full text

Validity and Reliability of Wearable Sensors for Continuous Postoperative Vital Signs Monitoring in Patients Recovering from Trauma Surgery by van Melzen, Rianne, Haveman, Marjolein E, Schuurmann, Richte C L, van Amsterdam, Kai, El Moumni, Mostafa, Tabak, Monique, Struys, Michel M R F, de Vries, Jean-Paul P M

“…(1) Background: Wearable sensors support healthcare professionals in clinical decision-making by measuring vital parameters such as heart rate (HR),…”
Get full text

Electroencephalography and Brain Oxygenation Monitoring in the Perioperative Period by Scheeren, Thomas W. L., Kuizenga, Merel H., Maurer, Holger, Struys, Michel M. R. F., Heringlake, Matthias

“…Maintaining brain function and integrity is a pivotal part of anesthesiological practice. The present overview aims to describe the current role of the 2 most…”
Get full text

Target-Controlled Infusion: A Mature Technology by Absalom, Anthony R., Glen, John (Iain) B., Zwart, Gerrit J. C., Schnider, Thomas W., Struys, Michel M. R. F.

“…Target-controlled infusions (TCIs) have been used in research and clinical practice for >2 decades. Nonapproved TCI software systems have been used during the…”
Get full text

Do all sedatives promote biological sleep electroencephalogram patterns? A machine learning framework to identify biological sleep promoting sedatives using electroencephalogram by Ramaswamy, Sowmya M, Kuizenga, Merel H, Weerink, Maud A S, Vereecke, Hugo E M, Nagaraj, Sunil B, Struys, Michel M R F

“…Sedatives are commonly used to promote sleep in intensive care unit patients. However, it is not clear whether sedation-induced states are similar to the…”
Get full text

Transmission and clearance of human papillomavirus infection in the oral cavity and its role in oropharyngeal carcinoma – A review by Wierzbicka, Małgorzata, San Giorgi, Michel R. M., Dikkers, Frederik G.

“…The majority of sexually active individuals becomes infected with human papillomavirus (HPV) at least once in their lifetime. Pathways for HPV transmission…”
Get full text

The History of Target-Controlled Infusion by Struys, Michel M. R. F., De Smet, Tom, Glen, John (Iain) B., Vereecke, Hugo E. M., Absalom, Anthony R., Schnider, Thomas W.

“…Target-controlled infusion (TCI) is a technique of infusing IV drugs to achieve a user-defined predicted (“target”) drug concentration in a specific body…”
Get full text

Implementing Wearable Sensors for Clinical Application at a Surgical Ward: Points to Consider before Starting by van Melzen, Rianne, Haveman, Marjolein E, Schuurmann, Richte C L, Struys, Michel M R F, de Vries, Jean-Paul P M

“…Incorporating technology into healthcare processes is necessary to ensure the availability of high-quality care in the future. Wearable sensors are an example…”
Get full text

The Impact of Different Anesthetics on the Distribution and Cytotoxic Function of NK Cell Subpopulations: An In Vitro Study by Vulcano, Tristan J, Abdulahad, Wayel H, van Meurs, Matijs, Jongman, Rianne M, Struys, Michel M R F, Bosch, Dirk J

“…Only some subpopulations of natural killer (NK) cells have cytotoxic functionality, and the effects of anesthetics on these subpopulations are unknown. This…”
Get full text

A General Purpose Pharmacokinetic Model for Propofol by Eleveld, Douglas J., Proost, Johannes H., Cortínez, Luis I., Absalom, Anthony R., Struys, Michel M. R. F.

“…BACKGROUND:Pharmacokinetic (PK) models are used to predict drug concentrations for infusion regimens for intraoperative displays and to calculate infusion…”
Get full text

Moderate-to-Deep Sedation Using Target-Controlled Infusions of Propofol and Remifentanil: Adverse Events and Risk Factors: A Retrospective Cohort Study of 2937 Procedures by Barends, Clemens R. M., Driesens, Mendy K., van Amsterdam, Kai, Struys, Michel M. R. F., Absalom, Anthony R.

“…BACKGROUND:In the University Medical Center Groningen in Groningen, the Netherlands, moderate-to-deep sedation is provided by nursing staff trained and…”
Get full text

System leaks and the loss of sevoflurane by Kalmar, Alain F., Teunkens, An, Rex, Steffen, Vereecke, Hugo, Mulier, Harold, Struys, Michel M. R. F.

Get full text

Urinary Biomarkers in a Living Donor Kidney Transplantation Cohort-Predictive Value on Graft Function by Huisman, G J Julia, Spraakman, Nora A, Koomen, Jeroen V, Talsma, A Marrit, Pol, Robert A, Berger, Stefan P, Leuvenink, Henri G D, Struys, Michel M R F, Nieuwenhuijs-Moeke, Gertrude J

“…Early non-invasive detection and prediction of graft function after kidney transplantation is essential since interventions might prevent further…”
Get full text

Ex Vivo Optimization of Donor Lungs with Inhaled Sevoflurane during Normothermic Ex Vivo Lung Perfusion (VITALISE): A Pilot and Feasibility Study in Sheep by Steinkühler, Timo, Yang, Shuqi, Hu, Michiel A, Jainandunsing, Jayant S, Jager, Neeltina M, Erasmus, Michiel E, Struys, Michel M R F, Bosch, Dirk J, van Meurs, Matijs, Jabaudon, Matthieu, Richard, Damien, Timens, Wim, Leuvenink, Henri G D, Nieuwenhuijs-Moeke, Gertrude J

“…Volatile anesthetics have been shown in different studies to reduce ischemia reperfusion injury (IRI). Ex vivo lung perfusion (EVLP) facilitates graft…”
Get full text

The Safety of Target-Controlled Infusions by Schnider, Thomas W., Minto, Charles F., Struys, Michel M. R. F., Absalom, Anthony R.

“…Target-controlled infusion (TCI) technology has been available in most countries worldwide for clinical use in anesthesia for approximately 2 decades. This…”
Get full text