Search Results - "Michel, Lea Vacca"

Dual orientation of the outer membrane lipoprotein Pal in Escherichia coli by Michel, Lea Vacca, Shaw, Juliana, MacPherson, Victoria, Barnard, David, Bettinger, John, D'Arcy, Brooke, Surendran, Naveen, Hellman, Judith, Pichichero, Michael E

“…Peptidoglycan associated lipoprotein (Pal) of Escherichia coli (E. coli) is a characteristic bacterial lipoprotein, with an N-terminal lipid moiety anchoring…”
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Dual Orientation of the Outer Membrane Lipoprotein P6 of Nontypeable Haemophilus influenzae by Michel, Lea Vacca, Snyder, Joy, Schmidt, Rachel, Milillo, Jennifer, Grimaldi, Kyle, Kalmeta, Breanna, Khan, M. Nadeem, Sharma, Sharad, Wright, Leslie Kate, Pichichero, Michael E

“…The majority of outer membrane (OM) lipoproteins in Gram-negative bacteria are tethered to the membrane via an attached lipid moiety and oriented facing in…”
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Vaccine candidate P6 of nontypable Haemophilus influenzae is not a transmembrane protein based on protein structural analysis by Michel, Lea Vacca, Kalmeta, Breanna, McCreary, Mark, Snyder, Joy, Craig, Paul, Pichichero, Michael E

“…Abstract P6 has been a vaccine candidate for nontypable Haemophilus influenzae (NTHi) based on its location on the outer membrane and immunogenicity. Because…”
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Covalent bonding of heme to protein prevents heme capture by nontypeable Haemophilus influenzae by Sgheiza, Valerie, Novick, Bethany, Stanton, Sarah, Pierce, Jeanetta, Kalmeta, Breanne, Holmquist, Melody Frink, Grimaldi, Kyle, Bren, Kara L., Michel, Lea Vacca

“…Nontypeable Haemophilus influenzae (NTHi) are Gram‐negative pathogens that contribute to a variety of diseases, including acute otitis media and chronic…”
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Outer membrane vesicles as molecular biomarkers for Gram-negative sepsis: Taking advantage of nature’s perfect packages by Michel, Lea Vacca, Gaborski, Thomas

“…Sepsis is an often life-threatening response to infection, occurring when host proinflammatory immune responses become abnormally elevated and dysregulated. To…”
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Haemophilus influenzae vaccine candidate outer membrane protein P6 is not conserved in all strains by Chang, Arthur, Kaur, Ravinder, Michel, Lea Vacca, Casey, Janet R., Pichichero, Michael E

“…An outer membrane protein of nontypeable Haemophilus influenzae (NTHi), P6, is a vaccine candidate because it has been characterized as conserved among all H…”
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Characterizing of the Effects of Pal‐Peptidoglycan Interaction by Liu, Xinbei, Lewis, Sean, Ward, Zack, Michel, Lea Vacca

“…Abstract only Peptidoglycan‐associated lipoprotein, Pal, is found in the outer membrane of Escherichia coli (E. coli) and other Gram‐negative bacteria…”
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Determining the role of Pal in Escherichia coli sepsis by Gallardo, Leslie, Bauer, Morgan, Pannullo, Nicole, Michel, Lea Vacca

“…Sepsis, a life‐threatening clinical condition affecting more than 1.5 million Americans per year, is defined as an over‐exuberant immune response to infection…”
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The effect of clinically relevant antibiotics on bacterial extracellular vesicle release from E. coli by Torabian, Panteha, Singh, Navraj, Crawford, James, Gonzalez, Gabriela, Burgado, Nicholas, Videva, Martina, Miller, Aidan, Perdue, Janai, Dinu, Milena, Pietropaoli, Anthony, Gaborski, Thomas, Michel, Lea Vacca

“…Sepsis, a leading cause of death in hospitals, can be defined as a dysregulated host inflammatory response to infection, which can lead to tissue damage, organ…”
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Looking at your lab through a new lens by Goudreau Collison, Christina, Michel, Lea Vacca

“…Restructuring the way you run and manage your lab can be a daunting task, but doing so is imperative for creating a research environment in which d/Deaf…”
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Elucidating the Protein‐Protein Interactions between Nontypeable Haemophilus Influenzae Outer Membrane Proteins Omp26 and Protein D by Farquharson, Kara Louise, Jackson, Niaya, Cheng, Susan Shi, Kaur, Ravinder, Michel, Lea Vacca

“…Abstract only Two leading protein vaccine candidates from Nontypeable Haemophilus Influenzae (NTHi) are outer membrane proteins Omp26 and Protein D. When…”
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Sputtering of Nanometric Films As a Tool to Enhance Antimicrobial Properties by Beckford, Daihlia, Ward, Zack, Phillips, Jacey, Repa, Kristen Stojak, Miller, Casey, Michel, Lea Vacca

“…Sputtering is a high vacuum physical vapor deposition technique during which atoms are excited from the surface of a target by a plasma. The energized atoms…”
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Probing the Pal‐peptidoglycan interaction by Ward, Zachary, Liu, Xinbei, Lewis, Sean D, LaClair, Ciara, Michel, Lea Vacca

“…Sepsis can be caused by a bacterial infection in the human bloodstream, upon which the immune system is over‐activated causing hyper‐inflammation throughout…”
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Elucidating the Intermolecular Interactions of a Cataract‐Causing Protein: γB Crystallin by Faraone, Julia, Bushunow, Symeon, Fadden, Aaron, Mills, Jeffrey L, Thurston, George, Michel, Lea Vacca

“…Gamma crystallin proteins can be found in the eye lens, helping to maintain transparency through their intermolecular interactions. Because crystallins remain…”
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Developing an Inclusive Workshop Series for Faculty Mentoring Diverse Research Students by Michel, Lea Vacca, Newman, Dina, Magalhaes, Rita Margarida Almeida, Wyatt, Brittney N

“…Undergraduate research can be an incredibly rewarding experience for both students and mentors. Many students who participate in undergraduate research find…”
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Probing the Effect of the Pal‐Peptidoglycan Interaction on Pal Release from Escherichia coli by Liu, Xinbei, Lewis, Sean D, Ward, Zachary, LaClair, Ciara, Michel, Lea Vacca

“…Peptidoglycan‐associated lipoprotein, Pal, is inserted into the outer membrane of Escherichia coli (E. coli) and other Gram‐negative bacteria. Under certain…”
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Investigating Pal's Interaction with Peptidoglycan by Lewis, Sean D, Liu, Xinbei, Ward, Zack, LaClair, Ciara, Michel, Lea Vacca

“…Peptidoglycan associated lipoprotein (Pal) has been shown to exhibit a unique dual orientation in Escherichia coli (E. coli). That is, Pal has two…”
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Understanding the Interactions Between γ‐B Crystallins by Melake, Abigail, Fraser, Olivia, Fadden, Aaron, Faraone, Julia, Williams, Zach, Mills, Jeffrey, Thurston, George, Michel, Lea Vacca

“…Abstract only The eye lens functions to focus light on the retina and is mostly composed of α, β, and γ‐crystallins, which are water‐soluble proteins…”
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Detecting Released Peptidoglycan Associated Lipoprotein (Pal) from Escherichia coli by Snyder, Emma, Zavorin, Mark, Farquaharson, Kara, Panullo, Nicole, Pichichero, Michael, Hellman, Judith, Michel, Lea Vacca

“…Gram‐negative sepsis can result from a bacterial infection, such as Escherichia coli (E. coli), which leads to an over‐exuberant inflammatory response in…”
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Ampicillin triggers the release of Pal in toxic vesicles from Escherichia coli by Michel, Lea Vacca, Gallardo, Leslie, Konovalova, Anna, Bauer, Morgan, Jackson, Niaya, Zavorin, Mark, McNamara, Carlie, Pierce, Jeanetta, Cheng, Susan, Snyder, Emma, Hellman, Judith, Pichichero, Michael E.

“…•The bacterial lipoprotein, Pal, is released from Escherichia coli under certain conditions and has been shown to contribute to sepsis-related…”
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