Search Results - "Michel, Auguet"

Different antinociceptive effects of botulinum toxin type A in inflammatory and peripheral polyneuropathic rat models by Favre-Guilmard, Christine, Auguet, Michel, Chabrier, Pierre-Etienne

“…In addition to inhibition of acetylcholine release in the neuromuscular junction botulinum toxin type A (BoNT-A) also inhibits the release of mediators…”
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IRC-082451, a novel multitargeting molecule, reduces L-DOPA-induced dyskinesias in MPTP Parkinsonian primates by Aron Badin, Romina, Spinnewyn, Brigitte, Gaillard, Marie-Claude, Jan, Caroline, Malgorn, Carole, Van Camp, Nadja, Dollé, Frédéric, Guillermier, Martine, Boulet, Sabrina, Bertrand, Anne, Savasta, Marc, Auguet, Michel, Brouillet, Emmanuel, Chabrier, Pierre-Etienne, Hantraye, Philippe

“…The development of dyskinesias following chronic L-DOPA replacement therapy remains a major problem in the long-term treatment of Parkinson's disease. This…”
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BN 80933, a Dual Inhibitor of Neuronal Nitric Oxide Synthase and Lipid Peroxidation: A Promising Neuroprotective Strategy by Chabrier, Pierre-Etienne, Auguet, Michel, Spinnewyn, Brigitte, Auvin, Serge, Cornet, Sylvie, Demerle-Pallardy, Caroline, Guilmard-Favre, Christine, Marin, Jean-Gregoire, Pignol, Bernadette, Gillard-Roubert, Veronique, Roussillot-Charnet, Christelle, Schulz, Jocelyne, Viossat, Isabelle, Bigg, Dennis, Moncada, Salvador

“…Nitric oxide (NO) and reactive oxygen species (ROS) act independently as well as cooperatively to induce neuronal death in acute neurological disorders…”
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53. Pharmacodynamic comparison of 3 marketed botulinum neurotoxin type A products by Cornet, Sylvie, Perier, Cindy, Auguet, Michel

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79. Is the analgesic mechanism of action of botulinum neurotoxin type A in rats unequivocal? by Favre-Guilmard, Christine, Perier, Cindy, Cornet, Sylvie, Auguet, Michel

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Induction of nitric oxide synthase by lipoteichoic acid from Staphylococcus aureus in vascular smooth muscle cells by Auguet, Michel, Lonchampt, Marie-Odile, Delaflotte, Sylvie, Goulin-Schulz, Jocelyne, Chabrier, Pierre Etienne, Braquet, Pierre

“…Inducible vascular nitric oxide synthase accounts for the contractile impairment observed in ondotoxemia. We provide evidence that lipoteichoic acid (LTA) from…”
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11. Functional characterization of BoNT/A subtypes by Auguet, Michel, Johnstone, Stephen, Palan, Shilpa, Wilson, Annie, Hedley, Diana, Fonfria, Elena, Hackett, Gavin, Liu, Sai, Donald, Sarah, Hornby, Fraser, Anderson, Dina, Beard, Matthew

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Novel azoles as potent and selective cannabinoid CB2 receptor agonists by Harnett, Jeremiah J., Dolo, Christine, Viossat, Isabelle, Auger, Florence, Ferrandis, Eric, Bigg, Dennis, Auguet, Michel, Auvin, Serge, Chabrier, Pierre-E.

“…[Display omitted] Novel azole compounds were prepared which demonstrated potent hCB2 binding activities with antioxidant activity for a selected compound…”
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IRC-082451, a novel multitargeting molecule, reduces L-DOPA-induced dyskinesias in MPTP Parkinsonian primates: New Anti-Dyskinetic Treatment for PD by Aron Badin, Romina, Spinnewyn, Brigitte, Gaillard, Marie-Claude, Jan, Caroline, Malgorn, Carole, van Camp, Nadja, Dollé, Frédéric, Guillermier, Martine, Boulet, Sabrina, Bertrand, Anne, Savasta, Marc, Auguet, Michel, Brouillet, Emmanuel, Chabrier, Pierre-Etienne, Hantraye, Philippe

“…The development of dyskinesias following chronic L-DOPA replacement therapy remains a major problem in the long-term treatment of Parkinson's disease. This…”
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BN82451 attenuates l-dopa-induced dyskinesia in 6-OHDA-lesioned rat model of Parkinson’s disease by Spinnewyn, Brigitte, Mautino, Gisele, Marin, Jean-Gregoire, Rocher, Marie Noëlle, Grandoulier, Anne Sophie, Ferrandis, Eric, Auguet, Michel, Chabrier, Pierre-Etienne

“…The development of l-dopa-induced dyskinesia (LID) remains a major problem in the long-term treatment of Parkinson’s disease (PD). This study aimed to assess…”
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Analgesic effects of Botulinum toxin A in an inflammatory pain model in rats: Comparison of Dysport ® and Botox ®; synergistic interaction with morphine by Michel, Auguet, Christine, Favre-Guilmard, Pierre-Etienne, Chabrier

“…The analgesic effect of Botulinum toxin A has been already demonstrated in different experimental models of pain. The aim of the present study was to compare…”
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Analgesic properties of botulinum toxin type A (Dysport ®) in paclitaxel-induced peripheral neuropathy in rats by Christine, Favre-Guilmard, Michel, Auguet, Pierre-Etienne, Chabrier

“…Botulinum toxin type A has been shown to elicit direct analgesic effect independent of anti-spastic activity. We have assessed the analgesic effect of a single…”
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Correction: IRC-082451, a Novel Multitargeting Molecule, Reduces L-DOPA-Induced Dyskinesias in MPTP Parkinsonian Primates by Aron Badin, Romina, Spinnewyn, Brigitte, Gaillard, Marie-Claude, Jan, Caroline, Malgorn, Carole, Van Camp, Nadja, Dollé, Frédéric, Guillermier, Martine, Boulet, Sabrina, Bertrand, Anne, Savasta, Marc, Auguet, Michel, Brouillet, Emmanuel, Chabrier, Pierre-Etienne, Hantraye, Philippe

“…Novel of 2-(iminomethyl)amino-phenyl derivatives intermidiates; e.g. US6586454; 5-membered heterocycle derivatives: e.g. WO01/26656, WO2005/035510; Use of…”
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An improved model to investigate the efficacy of antidyskinetic agents in hemiparkinsonian rats by Spinnewyn, Brigitte, Charnet, Christelle, Cornet, Sylvie, Roubert, Véronique, Chabrier, Pierre-Etienne, Auguet, Michel

“…A number of experimental models of L‐DOPA‐induced dyskinesia have been proposed, but these models result in a low to medium rate of dyskinetic animals with…”
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Endothelium independent protective effect of NG-monomethyl-L-arginine on endotoxin-induced alterations of vascular reactivity by Auguet, M, Guillon, J M, Delaflotte, S, Etiemble, E, Chabrier, P E, Braquet, P

“…The effects of NG-monomethyl-L-arginine (NMMA), a specific inhibitor of nitric oxide (NO) synthesis was tested on the endotoxin-induced alterations of…”
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Selective Inhibition of Inducible Nitric Oxide Synthase by Agmatine by Auguet, Michel, Viossat, Isabelle, Marin, Jean-Gregoire, Chabrier, Pierre-Etienne

“…Agmatine was about as potent as aminoguanidine to inhibit the activity of the inducible form of nitric oxide synthase (iNOS) in isolated rat aorta. Like…”
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The novel inhibitor of the heterotrimeric G-protein complex, BIM-46187, elicits anti-hyperalgesic properties and synergizes with morphine by Favre-Guilmard, Christine, Zeroual-Hider, Hamida, Soulard, Chantal, Touvay, Caroline, Chabrier, Pierre-Etienne, Prevost, Grégoire, Auguet, Michel

“…BIM-46187 (7-[2-amino-1-oxo-3-thio-propyl]-8-cyclohexylmethyl-2-phenyl-5,6,7,8-tetrahydro-imidazo-[1,2a]-pyrazine dimer, hydrochloride) is an inhibitor of the…”
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Butyl 2-(4-[1.1′-biphenyl]-4-yl-1H-imidazol-2-yl)ethylcarbamate, a potent sodium channel blocker for the treatment of neuropathic pain by Liberatore, Anne-Marie, Schulz, Jocelyne, Favre-Guilmard, Christine, Pommier, Jacques, Lannoy, Jacques, Pawlowski, Emilia, Barthelemy, Marie-Anne, Huchet, Marion, Auguet, Michel, Chabrier, Pierre-Etienne, Bigg, Dennis

“…A series of 4-arylimidazole carbamates was synthesized and their binding affinities to the site-2 sodium (Na +) channel were determined. SAR studies led to the…”
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Lack of evidence of direct mitochondrial involvement in the neuroprotective effect of minocycline by Cornet, Sylvie, Spinnewyn, Brigitte, Delaflotte, Sylvie, Charnet, Christelle, Roubert, Véronique, Favre, Christine, Hider, Hamida, Chabrier, P. Etienne, Auguet, Michel

“…Minocycline has been reported to exert neuroprotection through inhibition of inflammatory processes and of mitochondrial cell death pathway. To further…”
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Novel lipoic acid analogues that inhibit nitric oxide synthase by Harnett, Jeremiah J, Auguet, Michel, Viossat, Isabelle, Dolo, Christine, Bigg, Dennis, Chabrier, Pierre-E

“…The synthesis and biological activity of novel lipoic acid analogues are reported. Lipoic acid and structural homologues coupled to arylthiophene amidine via…”
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