Search Results - "Michel, A.D."

The pharmacological properties of the peptide, endothelin by Eglen, R.M., Michel, A.D., Sharif, N.A., Swank, S.R., Whiting, R.L.

“…1 The effect of endothelin (ET‐1) has been studied on isolated vascular and non‐vascular preparations, using both functional and competition radioligand…”
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Characteristics of 5‐HT3 binding sites in NG108‐15, NCB‐20 neuroblastoma cells and rat cerebral cortex using [3H]‐quipazine and [3H]‐GR65630 binding by Sharif, N.A., Wong, E.H.F., Loury, D.N., Stefanich, E., Michel, A.D., Eglen, R.M., Whiting, R.L.

“…1 The biochemical and pharmacological properties of 5‐HT3 receptors in homogenates of NG108‐15 and NCB‐20 neuroblastoma cells and rat cerebral cortex have been…”
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Characterization of the muscarinic receptor subtype mediating contractions of the guinea‐pig uterus by Eglen, R.M., Michel, A.D., Whiting, R.L.

“…The muscarinic receptor present on the guinea‐pig uterus has been characterized by use of both functional and radioligand binding studies. The contractile…”
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Determination of the volume-specific surface area by using transmission electron tomography for characterization and definition of nanomaterials by Van Doren, Elke A F, De Temmerman, Pieter-Jan R H, Francisco, Michel Abi Daoud, Mast, Jan

“…Transmission electron microscopy (TEM) remains an important technique to investigate the size, shape and surface characteristics of particles at the nanometer…”
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Blockade of Human P2X7 Receptor Function With a Monoclonal Antibody by Buell, G., Chessell, I.P., Michel, A.D., Collo, G., Salazzo, M., Herren, S., Gretener, D., Grahames, C., Kaur, R., Kosco-Vilbois, M.H., Humphrey, P.P.A.

“…A monoclonal antibody (MoAb) specific for the human P2X7receptor was generated in mice. As assessed by flow cytometry, the MoAb labeled human blood-derived…”
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Pharmacological characterization of angiotensin‐induced depolarizations of rat superior cervical ganglion in vitro by Hawcock, A.B., Barnes, J.C., Michel, A.D.

“…1 The depolarizing responses to angiotensin II and angiotensin III of the rat superior cervical ganglion have been characterized in vitro, by the use of…”
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Cloning and functional characterisation of the mouse P2X7 receptor by Chessell, I.P, Simon, J, Hibell, A.D, Michel, A.D, Barnard, E.A, Humphrey, P.P.A

“…We have isolated a 1785‐bp complementary DNA (cDNA) encoding the murine P2X7 receptor subunit from NTW8 mouse microglial cells. The encoded protein has 80% and…”
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Differential affinities of TRH analogs at the mammalian spinal cord TRH receptor: implications for therapy in spinal injuries by Sharif, N A, To, Z, Michel, A D, Whiting, R L

“…The equilibrium receptor binding properties and the pharmacological specificity of the spinal receptors for thyrotropin-releasing hormone (TRH) were…”
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Characterization and channel coupling of the P2Y12 nucleotide receptor of brain capillary endothelial cells by Simon, J., Filippov, A.K., Goransson, S., Wong, Y.H., Frelin, C., Michel, A.D., Brown, D.A., Barnard, E.A.

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Effects of metal cations on [3H]?,?-methylene ATP binding in rat vas deferens by Michel, A.D., Humphrey, P.P.A.

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Dynamics of P2X 7 receptor pore dilation: Pharmacological and functional consequences by Chessell, I.P., Grahames, C.B.A., Michel, A.D., Humphrey, P.P.A.

“…Abstract The biophysical and functional properties of the human P2X 7 receptor, expressed recombinantly in HEK‐293 cells or natively in THP‐1 pro‐monocytic…”
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Cibacron blue allosterically modulates the rat P2X4 receptor by MILLER, K. J, MICHEL, A. D, CHESSELL, I. P, HUMPHREY, P. P. A

“…We have used whole-cell patch clamp electrophysiology to characterise the actions of the P2 antagonist, cibacron blue, on the rat recombinant P2X4 receptor,…”
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Cibacron blue allosterically modulates the rat P2X 4 receptor by Miller, K.J, Michel, A.D, Chessell, I.P, Humphrey, P.P.A

“…We have used whole-cell patch clamp electrophysiology to characterise the actions of the P2 antagonist, cibacron blue, on the rat recombinant P2X 4 receptor,…”
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Cloning and functional characterisation of the mouse P2X 7 receptor by Chessell, I.P, Simon, J, Hibell, A.D, Michel, A.D, Barnard, E.A, Humphrey, P.P.A

“…We have isolated a 1785-bp complementary DNA (cDNA) encoding the murine P2X 7 receptor subunit from NTW8 mouse microglial cells. The encoded protein has 80%…”
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Dynamics of P2X7 receptor pore dilation: Pharmacological and functional consequences by Chessell, I.P., Grahames, C.B.A., Michel, A.D., Humphrey, P.P.A.

“…The biophysical and functional properties of the human P2X7 receptor, expressed recombinantly in HEK‐293 cells or natively in THP‐1 pro‐monocytic cells, were…”
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Functional evidence for multiple purinoceptor subtypes in the rat medial vestibular nucleus by Chessell, I.P, Michel, A.D, Humphrey, P.P.A

“…Extracellular recording techniques were used in brain slices to characterize excitatory responses produced by purine nucleotides in the rat medial vestibular…”
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The interaction of parafluorohexahydrosiladiphenidol at muscarinic receptors in vitro by Eglen, R.M., Michel, A.D., Montgomery, W.W., Kunysz, E.A., Machado, C.A., Whiting, R.L.

“…1 The antagonistic actions of parafluorohexahydrosiladiphenidol (pFHHSiD) at muscarinic receptors has been studied in cardiac muscle, smooth muscle and cell…”
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Blockade of human P2X7 receptor function with a monoclonal antibody by BUELL, G, CHESSELL, I. P, HUMPHREY, P. P. A, MICHEL, A. D, COLLO, G, SALAZZO, M, HERREN, S, GRETENER, D, GRAHAMES, C, KAUR, R, KOSCO-VILBOIS, M. H

“…A monoclonal antibody (MoAb) specific for the human P2X7 receptor was generated in mice. As assessed by flow cytometry, the MoAb labeled human blood-derived…”
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The selective P2X purinoceptor agonist, ?,?-methylene-L-adenosine 5?-triphosphate, discriminates between smooth muscle and neuronal P2X purinoceptors by Trezise, D.J., Michel, A.D., Grahames, C.B.A., Khakh, B.S., Surprenant, A., Humphrey, P.P.A.

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Evidence that [3H]‐α,β‐methylene ATP may label an endothelial‐derived cell line 5′‐nucleotidase with high affinity by Michel, A.D., Chau, N.‐M., Fan, T.‐P.D., Frost, E.E., Humphrey, P.P.A.

“…1 In membranes prepared from a permanent cell line of endothelial origin (WEC cells), [3H]‐α,β‐methylene ATP ([3H]‐α,β‐meATP) labelled high (pKd = 9.5; Bmax =…”
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