Search Results - "Michejda, C.J"
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VIP-ellipticine derivatives inhibit the growth of breast cancer cells
Published in Life sciences (1973) (19-07-2002)“…The effects of vasoactive intestinal peptide (VIP)-ellipticine (E) derivatives were investigated on breast cancer cells. VIP-ALALA-E and VIP-LALA-E inhibited…”
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288 POSTER Selective targeting of critical components of DNA replication by HKH40A (RTA 502)
Published in European journal of cancer supplements (01-11-2006)Get full text
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549 HKH40A, potent agent agaist GI cancers, targets p53 or when that is mutated, Akt
Published in European journal of cancer supplements (01-09-2004)Get full text
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Evidence for an unstable DNA adduct from N-nitroso-N-methylaniline
Published in Chemical research in toxicology (01-01-1990)“…N-Nitroso-N-methylaniline (NMA) is an esophageal carcinogen in F344 rats. Attempts to detect binding of NMA to DNA or RNA have not been successful. NMA is not…”
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Tumors in F344 rats by oral administration of 1,3-diethyltriazene
Published in Cancer letters (01-05-1987)“…A group of 20 male F344 rats was given by gavage a solution of 2.5 mg of 1,3-diethyltriazene in 0.2 ml corn oil twice a week for 20 weeks. Diethyltriazene is…”
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The effect of substituents in the aromatic ring on carcinogenicity of N-nitrosomethylaniline in F344 rats
Published in Carcinogenesis (New York) (1983)“…N-Nitroso-N-methylaniline (NMA) and N-nitroso-N-methyl-4-fluoroaniline (p-F-NMA), both non-mutagenic in Salmonella typhimurium and…”
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Derivatives of side-chain hydroxylated nitrosamines direct acting mutagens in Salmonella typhimurium
Published in Mutation research (01-08-1979)“…Methyl-(beta-tosyloxyethyl)nitrosamine and 3-methyl-4,5-dihydro-1,2,3-oxadiazolium tosylate are potent direct acting mutagens in the Ames assay, as is…”
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Mutagenicity of trialkyltriazenes: mutagenic potency of alkyldiazonium ions, the putative ultimate carcinogens from dialkylnitrosamines
Published in Mutation research (01-12-1980)“…Although aryldialkyltriazenes have been known for many years and their mutagenic, carcinogenic and carcinostatic properties have been investigated, almost…”
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Mutagenicity and rat-liver S9 demethylation kinetics of N-nitrosomethylaniline and its ring-substituted derivatives
Published in Mutation research (01-01-1981)“…N-nitrosomethylaniline, an esophageal carcinogen in the rat, was inactive in the Ames mutagenicity assay under all conditions examined. However, various…”
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