Search Results - "Michaud, Henri‐Alexandre"

Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies by Perrot, Ivan, Michaud, Henri-Alexandre, Giraudon-Paoli, Marc, Augier, Séverine, Docquier, Aurélie, Gros, Laurent, Courtois, Rachel, Déjou, Cécile, Jecko, Diana, Becquart, Ondine, Rispaud-Blanc, Hélène, Gauthier, Laurent, Rossi, Benjamin, Chanteux, Stéphanie, Gourdin, Nicolas, Amigues, Beatrice, Roussel, Alain, Bensussan, Armand, Eliaou, Jean-François, Bastid, Jérémy, Romagné, François, Morel, Yannis, Narni-Mancinelli, Emilie, Vivier, Eric, Paturel, Carine, Bonnefoy, Nathalie

“…Immune checkpoint inhibitors have revolutionized cancer treatment. However, many cancers are resistant to ICIs, and the targeting of additional inhibitory…”
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Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related ( ATR ) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer by Combès, Eve, Andrade, Augusto F, Tosi, Diego, Michaud, Henri-Alexandre, Coquel, Flavie, Garambois, Veronique, Desigaud, Delphine, Jarlier, Marta, Coquelle, Arnaud, Pasero, Philippe, Bonnefoy, Nathalie, Moreaux, Jerome, Martineau, Pierre, Del Rio, Maguy, Beijersbergen, Roderick L, Vezzio-Vie, Nadia, Gongora, Celine

“…Although many patients with colorectal cancer initially respond to the chemotherapeutic agent oxaliplatin, acquired resistance to this treatment remains a…”
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Identification of a regulatory Vδ1 gamma delta T cell subpopulation expressing CD73 in human breast cancer by Chabab, Ghita, Barjon, Clément, Abdellaoui, Naoill, Salvador‐Prince, Lucie, Dejou, Cécile, Michaud, Henri‐Alexandre, Boissière‐Michot, Florence, Lopez‐Crapez, Evelyne, Jacot, William, Pourquier, Didier, Bonnefoy, Nathalie, Lafont, Virginie

“…γδ T cells contribute to the immune response against many cancers, notably through their powerful effector functions that lead to the elimination of tumor…”
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A 31-plex panel for high-dimensional single-cell analysis of murine preclinical models of solid tumors by imaging mass cytometry by Glasson, Yaël, Chépeaux, Laure-Agnès, Dumé, Anne-Sophie, Jay, Philippe, Pirot, Nelly, Bonnefoy, Nathalie, Michaud, Henri-Alexandre

“…Currently, the study of resistance mechanisms and disease progression in cancer relies on the capacity to analyze tumors as a complex ecosystem of healthy and…”
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The IL-17B-IL-17 receptor B pathway promotes resistance to paclitaxel in breast tumors through activation of the ERK1/2 pathway by Laprevotte, Emilie, Cochaud, Stéphanie, du Manoir, Stanislas, Lapierre, Marion, Dejou, Cécile, Philippe, Marion, Giustiniani, Jérome, Frewer, Kathryn A, Sanders, Andrew J, Jiang, Wen G, Michaud, Henri-Alexandre, Colombo, Pierre-Emmanuel, Bensussan, Armand, Alberici, Gilles, Bastid, Jérémy, Eliaou, Jean-François, Bonnefoy, Nathalie

“…Interleukin 17B (IL-17B) is a pro-inflammatory cytokine that belongs to the IL-17 cytokines family and binds to IL-17 receptor B (IL-17RB). Here we found that…”
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IL-21 promotes the development of a CD73-positive Vγ9Vδ2 T cell regulatory population by Barjon, Clément, Michaud, Henri-Alexandre, Fages, Angeline, Dejou, Cécile, Zampieri, Alexandre, They, Laetitia, Gennetier, Aurélie, Sanchez, Françoise, Gros, Laurent, Eliaou, Jean-François, Bonnefoy, Nathalie, Lafont, Virginie

“…Vγ9Vδ2 T cells contribute to the immune response against many tumor types through their direct cytotoxic activity and capacity to regulate the biological…”
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An NF-κB–Dependent Role for JunB in the Induction of Proinflammatory Cytokines in LPS-Activated Bone Marrow–Derived Dendritic Cells by Gomard, Tiphanie, Michaud, Henri-Alexandre, Tempé, Denis, Thiolon, Kevin, Pelegrin, Mireia, Piechaczyk, Marc

“…Background Dendritic cells (DCs) play a key role in the induction of adaptive and memory immune responses. Upon encounter with pathogens, they undergo a…”
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A crucial role for infected-cell/antibody immune complexes in the enhancement of endogenous antiviral immunity by short passive immunotherapy by Michaud, Henri-Alexandre, Gomard, Tiphanie, Gros, Laurent, Thiolon, Kevin, Nasser, Roudaina, Jacquet, Chantal, Hernandez, Javier, Piechaczyk, Marc, Pelegrin, Mireia

“…Antiviral monoclonal antibodies (mAbs) represent promising therapeutics. However, most mAbs-based immunotherapies conducted so far have only considered the…”
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Long-Lasting Protective Antiviral Immunity Induced by Passive Immunotherapies Requires both Neutralizing and Effector Functions of the Administered Monoclonal Antibody by NASSER, Roudaina, PELEGRIN, Mireia, MICHAUD, Henri-Alexandre, PLAYS, Marc, PIECHACZYK, Marc, GROS, Laurent

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PD-1 blockade at the time of tumor escape potentiates the immune-mediated antitumor effects of a melanoma-targeting monoclonal antibody by They, Laetitia, Michaud, Henri-Alexandre, Becquart, Ondine, Lafont, Virginie, Guillot, Bernard, Boissière-Michot, Florence, Jarlier, Marta, Mollevi, Caroline, Eliaou, Jean-François, Bonnefoy, Nathalie, Gros, Laurent

“…Tumor antigen-targeting monoclonal antibodies (TA-targeting mAbs) are used as therapeutics in many malignancies and their capacity to mobilize the host…”
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First-line durvalumab and tremelimumab with chemotherapy in RAS-mutated metastatic colorectal cancer: a phase 1b/2 trial by Thibaudin, Marion, Fumet, Jean-David, Chibaudel, Benoist, Bennouna, Jaafar, Borg, Christophe, Martin-Babau, Jerome, Cohen, Romain, Fonck, Marianne, Taieb, Julien, Limagne, Emeric, Blanc, Julie, Ballot, Elise, Hampe, Léa, Bon, Marjorie, Daumoine, Susy, Peroz, Morgane, Mananet, Hugo, Derangère, Valentin, Boidot, Romain, Michaud, Henri-Alexandre, Laheurte, Caroline, Adotevi, Olivier, Bertaut, Aurélie, Truntzer, Caroline, Ghiringhelli, François

“…Although patients with microsatellite instable metastatic colorectal cancer (CRC) benefit from immune checkpoint blockade, chemotherapy with targeted therapies…”
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Functional specialization of short-lived and long-lived macrophage subsets in human tonsils by Alaoui, Lamine, Villar, Javiera, Leclere, Renaud, Le Gallou, Simon, Relouzat, Francis, Michaud, Henri-Alexandre, Tarte, Karin, Teissier, Natacha, Favier, Benoît, Roussel, Mikaël, Segura, Elodie

“…Macrophages play a central role in tissue homeostasis and host defense. However, the properties of human macrophages in non-diseased tissues remain poorly…”
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Endogenous Cytotoxic T-Cell Response Contributes to the Long-Term Antiretroviral Protection Induced by a Short Period of Antibody-Based Immunotherapy of Neonatally Infected Mice by GROS, Laurent, PELEGRIN, Mireia, MICHAUD, Henri-Alexandre, BIANCO, Stéphanie, HERNANDEZ, Javier, JACQUET, Chantal, PIECHACZYK, Marc

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Plasticity of γδ T Cells: Impact on the Anti-Tumor Response by Lafont, Virginie, Sanchez, Françoise, Laprevotte, Emilie, Michaud, Henri-Alexandre, Gros, Laurent, Eliaou, Jean-François, Bonnefoy, Nathalie

“…The tumor immune microenvironment contributes to tumor initiation, progression, and response to therapy. Among the immune cell subsets that play a role in the…”
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Single-cell high-dimensional imaging mass cytometry: one step beyond in oncology by Glasson, Yaël, Chépeaux, Laure-Agnès, Dumé, Anne-Sophie, Lafont, Virginie, Faget, Julien, Bonnefoy, Nathalie, Michaud, Henri-Alexandre

“…Solid tumors have a dynamic ecosystem in which malignant and non-malignant (endothelial, stromal, and immune) cell types constantly interact. Importantly, the…”
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Comprehensive analysis of cell lineages involved in giant cell arteritis pathogenesis using highly multiplexed imaging mass cytometry by Robert, Marie, Chépeaux, Laure-Agnès, Glasson, Yael, Dumé, Anne-Sophie, Sannier, Aurélie, Papo, Thomas, Bonnefoy, Nathalie, Michaud, Henri-Alexandre, Sacré, Karim

“…•High-plex imaging captures major information regarding GCA pathogenesis in a single tissue section.•High-plex imaging allows an unprecedented analysis of…”
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Higher Anti-Tumor Efficacy of the Dual HER3-EGFR Antibody MEHD7945a Combined with Ionizing Irradiation in Cervical Cancer Cells by Bourillon, Laura, Demontoy, Sylvain, Lenglet, Alexis, Zampieri, Alexandre, Fraisse, Julien, Jarlier, Marta, Boissière-Michot, Florence, Perrochia, Hélène, Rathat, Gauthier, Garambois, Véronique, Bonnefoy, Nathalie, Michaud, Henri-Alexandre, Chardès, Thierry, Tosi, Diego, Pèlegrin, André, Azria, David, Larbouret, Christel, Bourgier, Céline

“…The outcome of locally advanced cervical cancer (LACC) is dismal. Biomarkers are needed to individualize treatments and to improve patient outcomes. Here, we…”
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CD73: a new biomarker in triple-negative breast cancer by Lafont, Virginie, Michaud, Henri-Alexandre, Bonnefoy, Nathalie

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Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers by de Mulder, Miguel, SenGupta, Devi, Deeks, Steven G, Martin, Jeffrey N, Pilcher, Christopher D, Hecht, Frederick M, Sacha, Jonah B, Nixon, Douglas F, Michaud, Henri-Alexandre

“…Human endogenous retroviruses (HERVs) comprise approximately 8% of the human genome and while the majority are transcriptionally silent, the most recently…”
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Cutting edge: An antibody recognizing ancestral endogenous virus glycoproteins mediates antibody-dependent cellular cytotoxicity on HIV-1-infected cells by Michaud, Henri-Alexandre, SenGupta, Devi, de Mulder, Miguel, Deeks, Steven G, Martin, Jeffrey N, Kobie, James J, Sacha, Jonah B, Nixon, Douglas F

“…The failure of antiviral vaccines is often associated with rapid viral escape from specific immune responses. In the past, conserved epitope or algorithmic…”
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