Search Results - "Michaud, D P"
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Synthesis of a fluorescent derivatizing reagent, 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate, and its application for the analysis of hydrolysate amino acids via high-performance liquid chromatography
Published in Analytical biochemistry (01-06-1993)“…A highly reactive amine derivatizing reagent, 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate, has been synthesized. In a rapid, one-step procedure, the…”
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Synthesis of oligodeoxynucleoside methylphosphonates utilizing the tert-butylphenoxyacetyl group for exocyclic amine protection
Published in Nucleic acids research (11-08-1994)“…Oligodeoxynucleoside methylphosphonates were synthesized using methylphosphonamidite monomers incorporating the base labile tert-butylphenoxyacetyl (t-BPA)…”
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Effects of pH and salt concentration on the hydrolysis of a benzo[alpha]pyrene 7,8-diol-9,10-epoxide catalyzed by DNA and polyadenylic acid
Published in Chemico-biological interactions (01-01-1983)“…The time-dependent absorbance change that occurs when benzo[alpha]pyrene 7,8-diol-9,10-epoxide is added to solutions of calf thymus DNA has been shown, by an…”
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Mechanism of the Inhibition of Mutagenicity of a Benzo[a]pyrene 7,8-diol 9,10-epoxide by Riboflavin 5′-phosphate
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1982)“…Riboflavin 5′-phosphate (flavin mononucleotide; FMN) inhibits the mutagenicity of (± )-7β ,8α -dihydroxy-9α ,10α -epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene…”
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7-Dehydrocholesterol 5,6 beta-oxide as a mechanism-based inhibitor of microsomal cholesterol oxide hydrolase
Published in The Journal of biological chemistry (25-02-1986)“…7-Dehydrocholesterol 5,6 beta-oxide covalently modifies and inactivates the rat liver microsomal enzyme cholesterol oxide hydrolase. The covalent modification…”
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Distinct rat hepatic microsomal epoxide hydrolases catalyze the hydration of cholesterol 5,6 alpha-oxide and certain xenobiotic alkene and arene oxides
Published in Archives of biochemistry and biophysics (01-02-1983)“…Metabolism of cholesterol 5,6 alpha-oxide to the 5,6-glycol is catalyzed by a rat liver microsomal epoxide hydrolase that is distinct from the microsomal…”
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Properties of liver microsomal cholesterol 5,6-oxide hydrolase
Published in Archives of biochemistry and biophysics (15-08-1985)“…Cholestane 3 beta,5 alpha, 6 beta-triol has been identified as the exclusive product formed on hydration of cholesterol 5,6 alpha- and 5,6 beta-oxide catalyzed…”
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Recent developments in research on metabolites from Caribbean marine invertebrates
Published in Pure and applied chemistry (01-01-1981)“…Abstract…”
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Stereoselective synthesis and solvolytic behavior of the isomeric 7-dehydrocholesterol 5,6-oxides
Published in Journal of organic chemistry (01-05-1985)Get full text
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Recent developments in the chemistry, analysis and control for the manufacture of therapeutic-grade synthetic oligonucleotides
Published in Current opinion in drug discovery & development (01-11-2007)“…Significant developments in oligonucleotide chemistry, which occurred between 1980 and 2000, led to several oligonucleotide-based therapeutics entering…”
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Examination of ligand-ligand interactions by fast atom bombardment mass spectrometry
Published in Analytical chemistry (Washington) (15-05-1990)Get full text
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Steric controls in the preparation of 1-benzyl-1,4-dihydro-3-(2H)isoquinolones and 1-benzyl-1,2,4,5-tetrahydro(3H)-2-benzazepin-3-ones via Beckmann rearrangement
Published in Journal of heterocyclic chemistry (01-03-1978)“…The effect of substituents in the 1‐position of 2‐indanones and 2‐tetralones on the course of Beckmann rearrangement reactions was studied. Nmr spectral…”
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Marine natural products: dihydroxydeodactol monoacetate, a halogenated sesquiterpene ether from the sea hare aplysia dactylomela
Published in Journal of organic chemistry (01-04-1980)Get full text
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