Search Results - "Michaluk, Jerzy"
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Repeated Transcranial Direct Current Stimulation Induces Behavioral, Metabolic and Neurochemical Effects in Rats on High-Calorie Diet
Published in Frontiers in behavioral neuroscience (15-01-2018)“…Due to its high prevalence, obesity is considered an epidemic, which stimulated research on non-invasive methods to reduce excess body fat. Transcranial direct…”
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Changes in Monoaminergic Neurotransmission in an Animal Model of Osteoarthritis: The Role of Endocannabinoid Signaling
Published in Frontiers in molecular neuroscience (20-12-2018)“…Chronic pain is a main symptom of osteoarthritis (OA). Moreover, a high percentage of OA patients suffer from mental health problems. The endocannabinoid (EC)…”
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3
Protective effect of 1-methyl-1,2,3,4-tetrahydroisoquinoline against dopaminergic neurodegeneration in the extrapyramidal structures produced by intracerebral injection of rotenone
Published in The international journal of neuropsychopharmacology (01-06-2004)“…The aim of this paper was to investigate whether rotenone, a pesticide causing experimental parkinsonism, causes direct damage to dopaminergic structure when…”
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4
Effects of various Ca2+ channel antagonists on morphine analgesia, tolerance and dependence, and on blood pressure in the rat
Published in European journal of pharmacology (10-07-1998)“…Following the finding that nifedipine enhances morphine analgesia and prevents the development of dependence, we have now compared the effect of nifedipine…”
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Antidepressant-like Effect of Tetrahydroisoquinoline Amines in the Animal Model of Depressive Disorder Induced by Repeated Administration of a Low Dose of Reserpine: Behavioral and Neurochemical Studies in the Rat
Published in Neurotoxicity research (01-07-2014)“…Animal models are widely used to study antidepressant-like effect in rodents. However, it should be mentioned that pharmacological models do not always take…”
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1-Methyl-1,2,3,4-Tetrahydroisoquinoline, an Endogenous Amine with Unexpected Mechanism of Action: New Vistas of Therapeutic Application
Published in Neurotoxicity research (01-01-2014)“…This review outlines the effects of 1,2,3,4-tetrahydroisoquinoline (TIQ) and its derivative, 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ), endogenous…”
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Novel antagonists of 5-HT 6 and/or 5-HT 7 receptors affect the brain monoamines metabolism and enhance the anti-immobility activity of different antidepressants in rats
Published in Behavioural brain research (01-02-2019)“…The aim of the present study was to investigate and compare the ability of three novel 5-HT and/or 5-HT receptor antagonists as follows: PZ-668-a preferential…”
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8
Reduction of morphine dependence and potentiation of analgesia by chronic co-administration of nifedipine
Published in Psychopharmacologia (01-07-1993)“…Nifedipine, 5 mg/kg IP, potentiated the morphine-induced analgesia measured in the hot-plate, but not in the tail-flick test. Further experiments were carried…”
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Antidepressant-Like Effect of the Endogenous Neuroprotective Amine, 1MeTIQ in Clonidine-Induced Depression: Behavioral and Neurochemical Studies in Rats
Published in Neurotoxicity research (01-07-2017)“…Biogenic amines such as norepinephrine, dopamine, and serotonin play a well-described role in the treatment of mood disorders especially depression. Animal…”
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10
Novel antagonists of 5-HT6 and/or 5-HT7 receptors affect the brain monoamines metabolism and enhance the anti-immobility activity of different antidepressants in rats
Published in Behavioural brain research (01-02-2019)“…•PZ-668, PZ-1433, and ADN-1184 showed anti-immobility action in MED = 0.1 mg/kg.•5-HT6 and/or 5-HT7 antagonists affected brain monoamine metabolism in…”
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11
The impact of 1MeTIQ on the dopaminergic system function in the 6-OHDA model of Parkinson's disease
Published in Pharmacological reports (01-12-2016)“…Parkinson's disease (PD) is a progressive neurodegenerative disorder which is caused by degeneration of dopaminergic neurons of the nigrostriatal pathway. As a…”
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Acute treatment with doxorubicin induced neurochemical impairment of the function of dopamine system in rat brain structures
Published in Pharmacological reports (01-06-2016)“…The clinical studies have shown that chemotherapy may impair cognitive functions especially in the patients treated for breast cancer. It should be mention…”
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Study of a mechanism responsible for potential antidepressant activity of EMD 386088, a 5-HT6 partial agonist in rats
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-08-2016)“…It was shown that 5-HT 6 receptor agonists can exert pharmacological activity due to various modifications in monoamines’ level and metabolism activity in…”
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14
Antidepressant-like effect of 1,2,3,4-tetrahydroisoquinoline and its methyl derivative in animal models of depression
Published in Pharmacological reports (01-06-2017)“…Most of the currently used antidepressant drugs are monoamine-based compounds, acting by the inhibition of re-uptake or metabolism of noradrenaline (NA) and/or…”
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Neuroprotective Effect of the Endogenous Amine 1MeTIQ in an Animal Model of Parkinson’s Disease
Published in Neurotoxicity research (01-04-2016)“…Parkinson’s disease (PD) is a neurodegenerative disorder that is hallmarked by pathological changes associated with the death of dopaminergic neurons,…”
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16
Withdrawal from repeated administration of a low dose of reserpine induced opposing adaptive changes in the noradrenaline and serotonin system function: A behavioral and neurochemical ex vivo and in vivo studies in the rat
Published in Progress in neuro-psychopharmacology & biological psychiatry (03-03-2015)“…Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2) and monoamine releaser, so it can be used as a pharmacological model of depression…”
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Antidepressant-like activity of the endogenous amine, 1-methyl-1,2,3,4-tetrahydroisoquinoline in the behavioral despair test in the rat, and its neurochemical correlates: A comparison with the classical antidepressant, imipramine
Published in European journal of pharmacology (30-01-2013)“…Disturbances in noradrenergic and serotonergic transmissions have been postulated to form neurochemical background of depression…”
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Erratum to: Neuroprotective Effect of the Endogenous Amine 1MeTIQ in an Animal Model of Parkinson’s Disease
Published in Neurotoxicity research (01-08-2016)Get full text
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Study of a mechanism responsible for potential antidepressant activity of EMD 386088, a 5-HT sub(6) partial agonist in rats
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-08-2016)“…It was shown that 5-HT sub(6) receptor agonists can exert pharmacological activity due to various modifications in monoamines' level and metabolism activity in…”
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20
Study of a mechanism responsible for potential antidepressant activity of EMD 386088, a 5-HT^sub 6^ partial agonist in rats
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-08-2016)“…It was shown that 5-HT6 receptor agonists can exert pharmacological activity due to various modifications in monoamines' level and metabolism activity in rats'…”
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