Search Results - "Michalski, Bernadeta"
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The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity
Published in Immunity (Cambridge, Mass.) (15-05-2018)“…The triggering receptor expressed on myeloid cells 2 (TREM2) is a microglial innate immune receptor associated with a lethal form of early, progressive…”
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A Single Bout of High-intensity Interval Exercise Increases Corticospinal Excitability, Brain-derived Neurotrophic Factor, and Uncarboxylated Osteolcalcin in Sedentary, Healthy Males
Published in Neuroscience (15-06-2020)“…[Display omitted] •High-intensity interval exercise increased corticospinal excitability, BDNF and unOCN, and decreased cOCN.•Increases in BDNF were associated…”
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Differential deregulation of NGF and BDNF neurotrophins in a transgenic rat model of Alzheimer's disease
Published in Neurobiology of disease (01-12-2017)“…Evidence from human neuropathological studies indicates that the levels of the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor…”
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BDNF, proBDNF and IGF-1 serum levels in naïve and medicated subjects with autism
Published in Scientific reports (12-08-2022)“…Brain-derived neurotrophic factor (BDNF) and insulin-like growth factor 1 (IGF-1) promote the development and maintenance of neural circuits. Alterations in…”
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Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid
Published in Acta neuropathologica communications (20-01-2015)“…The molecular mechanisms underlying autistic behaviors remain to be elucidated. Mutations in genes linked to autism adversely affect molecules regulating…”
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Object recognition memory and BDNF expression are reduced in young TgCRND8 mice
Published in Neurobiology of aging (01-03-2012)“…Abstract The TgCRND8 mouse model of Alzheimer's disease exhibits progressive cortical and hippocampal β-amyloid accumulation, resulting in plaque pathology and…”
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No changes in corticospinal excitability, biochemical markers, and working memory after six weeks of high‐intensity interval training in sedentary males
Published in Physiological reports (01-06-2019)“…A single bout of aerobic exercise modulates corticospinal excitability, intracortical circuits, and serum biochemical markers such as brain‐derived…”
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Cerebrospinal Fluid proNGF: A Putative Biomarker for Early Alzheimer's Disease
Published in Current Alzheimer research (01-07-2016)“…The discovery of biomarkers for the onset of Alzheimer's disease (AD) is essential for disease modification strategies. To date, AD biomarker studies have…”
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The Precursor Pro-Nerve Growth Factor Is the Predominant Form of Nerve Growth Factor in Brain and Is Increased in Alzheimer's Disease
Published in Molecular and cellular neuroscience (01-08-2001)“…Nerve growth factor (NGF) is important for regulation, differentiation, and survival of peripheral and central nervous system neurons, including basal…”
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Differential effects of chronic immunosuppression on behavioral, epigenetic, and Alzheimer's disease-associated markers in 3xTg-AD mice
Published in Alzheimer's research & therapy (20-01-2021)“…Circulating autoantibodies and sex-dependent discrepancy in prevalence are unexplained phenomena of Alzheimer's disease (AD). Using the 3xTg-AD mouse model, we…”
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The nerve growth factor precursor proNGF exhibits neurotrophic activity but is less active than mature nerve growth factor
Published in Journal of neurochemistry (01-05-2004)“…Nerve growth factor (NGF) promotes neuronal survival and differentiation and stimulates neurite outgrowth. NGF is synthesized as a precursor, proNGF, which…”
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Pro-brain-derived neurotrophic factor is decreased in parietal cortex in Alzheimer’s disease
Published in Brain research. Molecular brain research. (17-03-2003)“…Brain-derived neurotrophic factor (BDNF) promotes the function and survival of the major neuronal types affected in Alzheimer disease, such as hippocampal,…”
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Nerve growth factor promoter activity revealed in mice expressing enhanced green fluorescent protein
Published in Journal of comparative neurology (1911) (01-09-2011)“…Nerve growth factor (NGF) and its precursor proNGF are perhaps the best described growth factors of the mammalian nervous system. There remains, however, a…”
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Differential gene expression profiling of short and long term denervated muscle
Published in The FASEB journal (01-01-2006)Get full text
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15
Sex-Dependent Differences in Serum Autoantibody Levels in the 3×Tg-AD Model of Alzheimer’s Disease
Published in The Journal of immunology (1950) (01-05-2022)“…Abstract Sex-dependent discrepancies in disease prevalence and serum autoantibody levels are observed in patients and animal models of Alzheimer’s disease…”
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Insulin‐Like Growth Factor and Insulin‐Like Growth Factor Receptor Expression in Human Idiopathic Autism Fusiform Gyrus Tissue
Published in Autism research (01-06-2020)“…Autism spectrum disorder (ASD) is believed to stem from defects in the establishment and maintenance of functional neuronal networks due to synaptic/spine…”
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The Effects of Physical Exercise and Cognitive Training on Memory and Neurotrophic Factors
Published in Journal of cognitive neuroscience (01-11-2017)“…This study examined the combined effect of physical exercise and cognitive training on memory and neurotrophic factors in healthy, young adults. Ninety-five…”
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Electrical muscle stimulation elevates intramuscular BDNF and GDNF mRNA following peripheral nerve injury and repair in rats
Published in Neuroscience (15-10-2016)“…Highlights • Daily electrical muscle stimulation enhanced early reinnervation after nerve injury. • GDNF and BDNF mRNA are upregulated in muscle but not distal…”
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Gonadal Hormones Contribute to Sex Differences in Autoimmunity, Pathology and Behaviour in the 3×Tg‐AD Mouse Model of Alzheimer’s Disease
Published in Alzheimer's & dementia (01-12-2022)“…Background Sex‐dependent discrepancies in prevalence and autoimmune markers are characteristics of Alzheimer’s disease (AD). Using the 3xTg‐AD mouse model, we…”
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Increased pro–nerve growth factor and decreased brain-derived neurotrophic factor in non–Alzheimer's disease tauopathies
Published in Neurobiology of aging (01-04-2014)“…Abstract Alterations in the expression and signaling of brain-derived neurotrophic factor (BDNF) and the precursor to nerve growth factor (NGF), proNGF, play a…”
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