Search Results - "Michalek, Carmela"
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Linker Hydrophilicity Modulates the Anticancer Activity of RGD–Cryptophycin Conjugates
Published in Chemistry : a European journal (13-01-2021)“…Most anticancer agents are hydrophobic and can easily penetrate the tumor cell membrane by passive diffusion. This may impede the development of highly…”
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Structure–Activity Relationship of Propargylamine‐Based HDAC Inhibitors
Published in ChemMedChem (19-12-2017)“…As histone deacetylases (HDACs) play an important role in the treatment of cancer, their selective inhibition has been the subject of various studies. These…”
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Purpureone, an antileishmanial ergochrome from the endophytic fungus Purpureocillium lilacinum
Published in Zeitschrift für Naturforschung. B, A journal of chemical sciences (01-11-2016)“…The ethyl acetate extracts prepared from the mycelia of three endophytic fungi and isolated from the roots of (Apocynaceae) were screened for their…”
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An RGD helper sequence in CagL of Helicobacter pylori assists in interactions with integrins and injection of CagA
Published in Frontiers in cellular and infection microbiology (2012)“…Helicobacter pylori is a specific gastric pathogen that colonizes the stomach in more than 50% of the world's human population. Infection with this bacterium…”
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A new xanthone derivative from twigs of Garcinia nobilis
Published in Natural product research (01-01-2014)“…Phytochemical investigation of the twigs of Garcinia nobilis led to the isolation of a new xanthone, named l-hydroxy-2,5-dimethoxyxanthone (1), together with…”
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Long-chain alkyl-substituted gentisic acid and benzoquinone derivatives from the root of Micronychia tsiramiramy (Anacardiaceae)
Published in Zeitschrift für Naturforschung. B, A journal of chemical sciences (01-04-2016)“…A new gentisic acid derivative named micronyc acid ( ) and a new 1,4-benzoquinone derivative named micronone ( ) have been isolated from the root of together…”
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