Search Results - "Michaelson, Samantha"

Non-classical actions of cholinesterases: Role in cellular differentiation, tumorigenesis and Alzheimer's disease by Small, David H., Michaelson, Samantha, Sberna, Gian

“…The cholinesterases are members of the serine hydrolase family, which utilizes a serine residue at the active site. Acetylcholinesterase (AChE) is…”
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DNA fragmentation pattern induced in thymocytes by sulphur mustard by Michaelson, Samantha

“…Sulphur mustard (HD) is a blister agent for which no specific therapy exists. The mechanism of cell injury caused by HD is not well understood. This study…”
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A protease activity associated with acetylcholinesterase releases the membrane-bound form of the amyloid protein precursor of Alzheimer's disease by Small, David H, Moir, Robert D, Fuller, Stephanie J, Michaelson, Samantha, Bush, Ashley I, Li, Qiao Xin, Milward, Elizabeth, Hilbich, Caroline, Weidemann, Andreas

“…Amyloid deposits in the brains of patients with Alzheimer's disease (AD) contain a protein (beta A4) which is abnormally cleaved from a larger transmembrane…”
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A protease is recovered with a dimeric form of acetylcholinesterase in fetal bovine serum by Michaelson, S, Small, D H

“…A protease activity which co-purified with affinity-purified fetal bovine serum acetylcholinesterase (AChE) has been shown to release the amyloid protein…”
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Expression of dimeric and tetrameric acetylcholinesterase isoforms on the surface of cultured bovine adrenal chromaffin cells by Michaelson, S, Small, D H, Livett, B G

“…Acetylcholinesterase is a highly polymorphic enzyme, which can be anchored to the cell surface through several different mechanisms. Dimeric (G2)…”
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A second site of action of soman on acetylcholinesterase by Michaelson, S, Gray, P J

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Regulation of acetylcholinesterase secretion from perfused bovine adrenal gland and isolated bovine chromaffin cells by Small, D H, Michaelson, S, Marley, P D, Friedhuber, A, Hocking, A, Livett, B G

“…The secretion of acetylcholinesterase (AChE) was studied in an isolated perfused bovine adrenal gland preparation and in cultured bovine adrenal medullary…”
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