Search Results - "Michael O’Connor, J."
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PARP14 regulates cyclin D1 expression to promote cell-cycle progression
Published in Oncogene (29-07-2021)“…Cyclin D1 is an essential regulator of the G1–S cell-cycle transition and is overexpressed in many cancers. Expression of cyclin D1 is under tight cellular…”
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2
Gold nanoparticle imaging and radiotherapy of brain tumors in mice
Published in Nanomedicine (London, England) (01-10-2013)“…To test intravenously injected gold nanoparticles for x-ray imaging and radiotherapy enhancement of large, imminently lethal, intracerebral malignant gliomas…”
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3
NFκB regulates p21 expression and controls DNA damage-induced leukemic differentiation
Published in Oncogene (05-07-2018)“…DNA damage exposure is a major modifier of cell fate in both normal and cancer tissues. In response to DNA damage, myeloid leukemia cells activate a poorly…”
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4
PARI (PARPBP) suppresses replication stress-induced myeloid differentiation in leukemia cells
Published in Oncogene (01-07-2019)“…Hyperproliferative cancer cells face increased replication stress, which can result in accumulation of DNA damage. As DNA damage can arrest proliferation, and,…”
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Infrared-transparent gold nanoparticles converted by tumors to infrared absorbers cure tumors in mice by photothermal therapy
Published in PloS one (10-02-2014)“…Gold nanoparticles (AuNPs) absorb light and can be used to heat and ablate tumors. The "tissue window" at ∼ 800 nm (near infrared, NIR) is optimal for best…”
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Characterization of scatter in cone-beam CT breast imaging: Comparison of experimental measurements and Monte Carlo simulation
Published in Medical physics (Lancaster) (01-03-2009)“…It is commonly understood that scattered radiation in x-ray computed tomography (CT) degrades the reconstructed image. As a precursor to developing scatter…”
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7
Penalized Maximum Likelihood Reconstruction for Improved Microcalcification Detection in Breast Tomosynthesis
Published in IEEE transactions on medical imaging (01-04-2011)“…We examined the application of an iterative penalized maximum likelihood (PML) reconstruction method for improved detectability of microcalcifications (MCs) in…”
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8
Evaluation of a variable dose acquisition technique for microcalcification and mass detection in digital breast tomosynthesis
Published in Medical physics (Lancaster) (01-06-2009)“…In this article the authors evaluate a recently proposed variable dose (VD)-digital breast tomosynthesis (DBT) acquisition technique in terms of the detection…”
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Effect of Blood Culture Contamination on Antibiotic Use in an Institution With Rapid Laboratory Methods and Phone-Based Clinical Follow-up of Blood Culture Results
Published in Open forum infectious diseases (01-10-2022)“…In a multivariate analysis of 30 574 blood culture (BC) results, BC contamination was associated with only a small increase in antibiotic length of therapy…”
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10
A method to synchronize signals from multiple patient monitoring devices through a single input channel for inclusion in list-mode acquisitions
Published in Medical physics (Lancaster) (01-12-2013)“…Purpose: This technical note documents a method that the authors developed for combining a signal to synchronize a patient-monitoring device with a second…”
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11
Mortality after Epilepsy Surgery
Published in Epilepsia (Copenhagen) (01-12-2005)“…Mortality rates are higher in people with refractory epilepsy than in the general population. We assessed mortality rates in a prospectively followed cohort…”
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12
Distinguishing regulatory DNA from neutral sites
Published in Genome research (01-01-2003)“…We explore several computational approaches to analyzing interspecies genomic sequence alignments, aiming to distinguish regulatory regions from neutrally…”
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13
Microglia Express CCR5, CXCR4, and CCR3, but of These, CCR5 Is the Principal Coreceptor for Human Immunodeficiency Virus Type 1 Dementia Isolates
Published in Journal of Virology (01-01-1999)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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14
Generation of voxelized breast phantoms from surgical mastectomy specimens
Published in Medical physics (Lancaster) (01-04-2013)“…Purpose: In the research and development of dedicated tomographic breast imaging systems, digital breast object models, also known as digital phantoms, are…”
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15
Value of non-invasive testing when there are independent bitemporal seizures in the scalp EEG
Published in Epilepsy research (01-02-2006)“…We investigated the value of non-invasive data for predicting the outcome of intracranial EEG and anterior temporal lobectomy (ATL) (follow-up > 1 year) in…”
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Lack of Association Between an Interleukin 1 Beta (IL‐1β) Gene Variation and Refractory Temporal Lobe Epilepsy
Published in Epilepsia (Copenhagen) (01-06-2001)“…Purpose: We attempted to confirm recent findings of Kanemoto et al. that demonstrated a positive association (p < 0.017) between a polymorphism in the promoter…”
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Lack of association between variations in the brain-derived neurotrophic factor (BDNF) gene and temporal lobe epilepsy
Published in Epilepsy research (01-08-2005)“…Recently, an association between the C240T polymorphism in the brain-derived neurotrophic factor (BDNF) gene and partial epilepsy was demonstrated in a…”
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18
Language before and after temporal lobectomy: specificity of acute changes and relation to early risk factors
Published in Epilepsia (Copenhagen) (01-11-1995)“…We evaluated language functions in 154 patients with left hemisphere speech dominance undergoing anterior temporal lobectomy (ATL). Measures of phonemic and…”
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The effect of human herpesvirus-6 (HHV-6) on cultured human neural cells: oligodendrocytes and microglia
Published in Journal of neurovirology (01-10-1998)“…Human herpesvirus-6 (HHV-6) is a betaherpesvirus that has been frequently associated with pediatric encephalitis. In 1995 Challoner et al reported that HHV-6…”
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Evaluation of antigen-capture ELISA and immunohistochemical methods for avian surveillance of West Nile virus
Published in Journal of veterinary diagnostic investigation (2006)“…Accurate detection of West Nile virus (WNV) in corvids is essential for monitoring the spread of virus during the mosquito season. Viremia in corvids is very…”
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